UniProtKB - B2R8L3 (B2R8L3_HUMAN)
Protein
Submitted name:
cDNA, FLJ93955, highly similar to Homo sapiens beta-transducin repeat containing (BTRC), transcript variant 2, mRNA
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- protein dimerization activity Source: InterPro
Enzyme and pathway databases
SignaLinki | B2R8L3 |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA, FLJ93955, highly similar to Homo sapiens beta-transducin repeat containing (BTRC), transcript variant 2, mRNAImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 154 – 192 | F-boxInterPro annotationAdd BLAST | 39 | |
Domaini | 263 – 554 | WD_REPEATS_REGIONInterPro annotationAdd BLAST | 292 | |
Repeati | 276 – 293 | WDPROSITE-ProRule annotationAdd BLAST | 18 | |
Repeati | 303 – 342 | WDPROSITE-ProRule annotationAdd BLAST | 40 | |
Repeati | 343 – 382 | WDPROSITE-ProRule annotationAdd BLAST | 40 | |
Repeati | 386 – 425 | WDPROSITE-ProRule annotationAdd BLAST | 40 | |
Repeati | 426 – 465 | WDPROSITE-ProRule annotationAdd BLAST | 40 | |
Repeati | 466 – 497 | WDPROSITE-ProRule annotationAdd BLAST | 32 | |
Repeati | 515 – 554 | WDPROSITE-ProRule annotationAdd BLAST | 40 |
Keywords - Domaini
RepeatARBA annotation, WD repeatPROSITE-ProRule annotationARBA annotationPhylogenomic databases
OrthoDBi | 666965at2759 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR021977, Beta-TrCP_D IPR036047, F-box-like_dom_sf IPR001810, F-box_dom IPR020472, G-protein_beta_WD-40_rep IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF12125, Beta-TrCP_D, 1 hit PF12937, F-box-like, 1 hit PF00400, WD40, 6 hits |
PRINTSi | PR00320, GPROTEINBRPT |
SMARTi | View protein in SMART SM01028, Beta-TrCP_D, 1 hit SM00256, FBOX, 1 hit SM00320, WD40, 7 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit SSF81383, SSF81383, 1 hit |
PROSITEi | View protein in PROSITE PS50181, FBOX, 1 hit PS00678, WD_REPEATS_1, 6 hits PS50082, WD_REPEATS_2, 7 hits PS50294, WD_REPEATS_REGION, 1 hit |
i Sequence
Sequence statusi: Complete.
B2R8L3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDPAEAVLQE KALKFMNSSE REDCNNGEPP RKIIPEKNSL RQTYNSCARL
60 70 80 90 100
CLNQETVCLA STAMKTENCV AKTKLANGTS SMIVPKQRKL SASYEKEKEL
110 120 130 140 150
CVKYFEQWSE SDQVEFVEHL ISQMCHYQHG HINSYLKPML QRDFITALPA
160 170 180 190 200
RGLDHIAENI LSYLDAKSLC AAELVCKEWY RVTSDGMLWK KLIERMVRTD
210 220 230 240 250
SLWRGLAERR GWGQYLFKNK PPDGNAPPNS FYRALYPKII QDIETIESNW
260 270 280 290 300
RCGRHSLQRI HCRSETSKGV YCLQYDDQKI VSGLRDNTIK IWDKNTLECK
310 320 330 340 350
RILTGHTGSV LCLQYDERVI ITGSSDSTVR VWDVNTGEML NTLIHHCEAV
360 370 380 390 400
LHLRFNNGMM VTCSKDRSVA VWDMASPTDI TLRRVLVGHR AAVNVVDFDD
410 420 430 440 450
KYIVSASGDR TIKVWNTSTC EFVRTLNGHK RGIACLQYRD RLVVSGSSDN
460 470 480 490 500
TIRLWDIECG ACLRVLEGHE ELVRCIRFDN KRIVSGAYDG KIKVWDLVAA
510 520 530 540 550
LDPRAPAGTL CLRTLVEHSG RVFRLQFDEF QIVSSSHDDT ILIWDFLNDP
560
AAQAEPPRSP SRTYTYISR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK313417 mRNA Translation: BAG36210.1 |
RefSeqi | NP_001243785.1, NM_001256856.1 NP_003930.1, NM_003939.4 NP_378663.1, NM_033637.3 |
Genome annotation databases
GeneIDi | 8945 |
KEGGi | hsa:8945 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK313417 mRNA Translation: BAG36210.1 |
RefSeqi | NP_001243785.1, NM_001256856.1 NP_003930.1, NM_003939.4 NP_378663.1, NM_033637.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | B2R8L3 |
Genome annotation databases
GeneIDi | 8945 |
KEGGi | hsa:8945 |
Organism-specific databases
CTDi | 8945 |
Phylogenomic databases
OrthoDBi | 666965at2759 |
Enzyme and pathway databases
SignaLinki | B2R8L3 |
Miscellaneous databases
BioGRID-ORCSi | 8945, 12 hits in 851 CRISPR screens |
GenomeRNAii | 8945 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR021977, Beta-TrCP_D IPR036047, F-box-like_dom_sf IPR001810, F-box_dom IPR020472, G-protein_beta_WD-40_rep IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF12125, Beta-TrCP_D, 1 hit PF12937, F-box-like, 1 hit PF00400, WD40, 6 hits |
PRINTSi | PR00320, GPROTEINBRPT |
SMARTi | View protein in SMART SM01028, Beta-TrCP_D, 1 hit SM00256, FBOX, 1 hit SM00320, WD40, 7 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit SSF81383, SSF81383, 1 hit |
PROSITEi | View protein in PROSITE PS50181, FBOX, 1 hit PS00678, WD_REPEATS_1, 6 hits PS50082, WD_REPEATS_2, 7 hits PS50294, WD_REPEATS_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B2R8L3_HUMAN | |
Accessioni | B2R8L3Primary (citable) accession number: B2R8L3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 1, 2008 |
Last sequence update: | July 1, 2008 | |
Last modified: | December 2, 2020 | |
This is version 70 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |