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Entry version 63 (26 Feb 2020)
Sequence version 1 (10 Jun 2008)
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Protein
Submitted name:

DewG

Gene

impK

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DewGImported
Submitted name:
DotU family type IV/VI secretion system proteinImported
Submitted name:
E9Imported
Submitted name:
EvfFKImported
Submitted name:
Putative type VI secretion system proteinImported
Submitted name:
Type VI secretion system protein ImpKImported
Submitted name:
XmtGImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:impKImported
Synonyms:dewGImported, evfKImported, xmtGImported
ORF Names:AWG78_006815Imported, B6V57_01210Imported, C4K41_24435Imported, CT146_25970Imported, DNR41_24990Imported, DU333_25275Imported, EPS94_24390Imported, EYX99_16250Imported, FQU83_21605Imported, HmCmsJML146_00568Imported, MS8345_00224Imported, NCTC10767_04022Imported, NCTC9434_02668Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000306171 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000233584 Componenti: Chromosome
  • UP000315141 Componenti: Chromosome
  • UP000254730 Componenti: Unassembled WGS sequence
  • UP000254647 Componenti: Unassembled WGS sequence
  • UP000238807 Componenti: Unassembled WGS sequence
  • UP000272659 Componenti: Unassembled WGS sequence
  • UP000324147 Componenti: Chromosome
  • UP000076551 Componenti: Unassembled WGS sequence
  • UP000229602 Componenti: Unassembled WGS sequence
  • UP000290055 Componenti: Unassembled WGS sequence
  • UP000304638 Componenti: Unassembled WGS sequence
  • UP000249503 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei214 – 236HelicalSequence analysisAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini34 – 234DotUInterPro annotationAdd BLAST201

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105NIK Bacteria
COG3455 LUCA

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.590, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017732 T4/T6SS_DotU
IPR038522 T4/T6SS_DotU_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09850 DotU, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03349 IV_VI_DotU, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B2LWF8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDMSEASVF PVEPESGTPG RQYRLALRGN SLNPMIDAAT PLLGMVMRLS
60 70 80 90 100
TMNSQAMPEH LFTQVVTDVQ AVEQLLQEQG YEPGVIVSFR YILCTFIDEA
110 120 130 140 150
ALGNGWSNKN EWIKQSLLVH FHNEAWGGEK VFILLERLIR EPVRYQDLLE
160 170 180 190 200
FLYLCFSLGF RGRYKVAIQQ QDEFERIYQR LHHALHKLRG DAPFPLLHQK
210 220 230 240 250
NNIQGGRYQL IRRLTIKHVL CGGLVVLTVF YLFYLLRLDS QTQDILHQLN

KLLR
Length:254
Mass (Da):29,416
Last modified:June 10, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0EBB40E2BC3EE7BC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EU590041 Genomic DNA Translation: ACB97674.1
KF678350 Genomic DNA Translation: AHW84508.1
KF678352 Genomic DNA Translation: AHW84553.1
KM251715 Genomic DNA Translation: AIU68809.1
CP025401 Genomic DNA Translation: AUG91872.1
CP020545 Genomic DNA Translation: AWG05237.1
BFRA01000023 Genomic DNA Translation: GCZ96598.1
PENJ01000028 Genomic DNA Translation: PIM20835.1
PSNQ01000034 Genomic DNA Translation: PPE25640.1
CP042246 Genomic DNA Translation: QDX38152.1
QLAC01000028 Genomic DNA Translation: RAH18859.1
RRUU01000020 Genomic DNA Translation: RRK87410.1
LVSP02000001 Genomic DNA Translation: RRO49278.1
SCIX01000029 Genomic DNA Translation: RXB41438.1
UFXW01000004 Genomic DNA Translation: STC86461.1
UGFV01000001 Genomic DNA Translation: STN17908.1
SSQV01000058 Genomic DNA Translation: TIJ88850.1

NCBI Reference Sequences

More...
RefSeqi
WP_001282178.1, NZ_VRWE01000030.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CRL89784; CRL89784; AL505_280017

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|562.7283.peg.3885

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU590041 Genomic DNA Translation: ACB97674.1
KF678350 Genomic DNA Translation: AHW84508.1
KF678352 Genomic DNA Translation: AHW84553.1
KM251715 Genomic DNA Translation: AIU68809.1
CP025401 Genomic DNA Translation: AUG91872.1
CP020545 Genomic DNA Translation: AWG05237.1
BFRA01000023 Genomic DNA Translation: GCZ96598.1
PENJ01000028 Genomic DNA Translation: PIM20835.1
PSNQ01000034 Genomic DNA Translation: PPE25640.1
CP042246 Genomic DNA Translation: QDX38152.1
QLAC01000028 Genomic DNA Translation: RAH18859.1
RRUU01000020 Genomic DNA Translation: RRK87410.1
LVSP02000001 Genomic DNA Translation: RRO49278.1
SCIX01000029 Genomic DNA Translation: RXB41438.1
UFXW01000004 Genomic DNA Translation: STC86461.1
UGFV01000001 Genomic DNA Translation: STN17908.1
SSQV01000058 Genomic DNA Translation: TIJ88850.1
RefSeqiWP_001282178.1, NZ_VRWE01000030.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiCRL89784; CRL89784; AL505_280017
PATRICifig|562.7283.peg.3885

Phylogenomic databases

eggNOGiENOG4105NIK Bacteria
COG3455 LUCA

Family and domain databases

Gene3Di1.25.40.590, 1 hit
InterProiView protein in InterPro
IPR017732 T4/T6SS_DotU
IPR038522 T4/T6SS_DotU_sf
PfamiView protein in Pfam
PF09850 DotU, 1 hit
TIGRFAMsiTIGR03349 IV_VI_DotU, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB2LWF8_ECOLX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B2LWF8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: February 26, 2020
This is version 63 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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