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UniProtKB - B2L7U8 (B2L7U8_9PRIM)

Entry version 20 (12 Aug 2020)
Sequence version 1 (10 Jun 2008)
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Protein
Submitted name:

Enamelin

Gene

ENAM

Organism
Gorilla gorilla (western gorilla)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
EnamelinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ENAMImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGorilla gorilla (western gorilla)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9593 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Gorilla

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni77 – 332DisorderedSequence analysisAdd BLAST256
Regioni377 – 707DisorderedSequence analysisAdd BLAST331
Regioni727 – 748DisorderedSequence analysisAdd BLAST22
Regioni771 – 822DisorderedSequence analysisAdd BLAST52
Regioni874 – 1093DisorderedSequence analysisAdd BLAST220

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi90 – 104Pro-richSequence analysisAdd BLAST15
Compositional biasi120 – 152PolarSequence analysisAdd BLAST33
Compositional biasi174 – 188Pro-richSequence analysisAdd BLAST15
Compositional biasi218 – 236PolyampholyteSequence analysisAdd BLAST19
Compositional biasi239 – 286PolarSequence analysisAdd BLAST48
Compositional biasi299 – 332PolarSequence analysisAdd BLAST34
Compositional biasi449 – 470PolarSequence analysisAdd BLAST22
Compositional biasi504 – 519PolarSequence analysisAdd BLAST16
Compositional biasi571 – 591PolyampholyteSequence analysisAdd BLAST21
Compositional biasi630 – 647PolarSequence analysisAdd BLAST18
Compositional biasi687 – 701PolarSequence analysisAdd BLAST15
Compositional biasi771 – 785PolyampholyteSequence analysisAdd BLAST15
Compositional biasi897 – 938PolarSequence analysisAdd BLAST42
Compositional biasi948 – 963PolarSequence analysisAdd BLAST16
Compositional biasi999 – 1013PolarSequence analysisAdd BLAST15
Compositional biasi1028 – 1053PolarSequence analysisAdd BLAST26
Compositional biasi1063 – 1093PolarSequence analysisAdd BLAST31

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR015673, Enamelin

The PANTHER Classification System

More...PANTHERi		PTHR16784, PTHR16784, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15362, Enamelin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

B2L7U8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLVLRCRLGT SFPKLDNLVP KGKMKILLVF LGLLGNSVAM PMHMPRMPGF 
        60         70         80         90        100
SSKSEEMMRY NQFNFMNGPH MAHLGPFFGN GLPQQFPQYQ MPMWPQPPPN 
       110        120        130        140        150
TWHPRKSSAP KRHNKTDQTQ ETQKPNQTQS KKPPQKRPLK QPSHNQPQPE 
       160        170        180        190        200
EEAQPPQAFP PFGNGLFPYQ QPPWQIPQRL PPPGYGRPPI SNEEGGNPYF 
       210        220        230        240        250
GYFGYHGFGG RPPYYSEEMF EQDFEKPKEE DPPKAESPGT EPTANSTVTE 
       260        270        280        290        300
TNSTQPNPKG SQGGNDTSPT GNSTPGLNTG NNPPVQNGIG PLPAVNASGQ 
       310        320        330        340        350
GGPGSQIPWR PSQPNIHENH PYPNIRNFPS GTQWYFTGTV MGHRQNRPFY 
       360        370        380        390        400
RNQQVQRGPR WNSFAWERKQ VARPGNPVYH KAYPPTSRGN YPNYAGNPAN 
       410        420        430        440        450
LRRKPQGPNK HPXXXXXXXX XXXXXXXXXX EKIQNPREKP LGPKEQIIVP 
       460        470        480        490        500
TKNPTSPWRN SQQYEVNKSN YKLPHSEGYM PVPNFNSVDQ HENSYYPRGD 
       510        520        530        540        550
SRKVPNSDGQ TQSQNLPKGI VLGSRRMPYE SETNQPELKH SSYQPAVYPE 
       560        570        580        590        600
EIPSPAKEHF PAGRNTWDHQ EISPPFKEDP GRQEEHLPHP SHGSRGSVFY 
       610        620        630        640        650
PEYNPYDPRE NSPYLRGNTW DERDDSPNTM GQKESPLYPI NTPDQKETVP 
       660        670        680        690        700
YNEEDPVDPT GDEVFPGQNR WGEELSFKGG PTVRHYEGEQ YTSNQPKEYL 
       710        720        730        740        750
PYSLDNPSKP REDFYYSEFY PWSPDENFPS YNTAPTMPPP IESRGYYVNN 
       760        770        780        790        800
AAGPEESTLF PSRNSWDHRI QAQGQRERRP YFNRKIWDQA THLQKAPARP 
       810        820        830        840        850
PDQKGNQPYY SNTPAGLQKN PIWHEGENLN YGMQITRTNS PEREHSSFPN 
       860        870        880        890        900
FIPPSYPSGQ KEAHLFHLSQ RGSCCAGSST GPKDNPLALQ DYTPSYGLAP 
       910        920        930        940        950
GENQDTSPLY TDGSHTKQTR DIISPTSILP GQRNSSEKRE SQNPFRDDVS 
       960        970        980        990       1000
TLRRNTPCSI KNQLGQKEIM PFPEASSLQS KNTPCLKNDL GGDGNNILEQ 
      1010       1020       1030       1040       1050
VFEDNQLNER TVDLTPEQLV IGTPDEGSNP EGIQSQVQEN ESERQQQRPS 
      1060       1070       1080       1090       1100
NILHLPCFGS KLAKHHSSTT GTPSSDGRQS PFDGDSITPT ENPNTLVELA 
      1110       1120       1130       1140 
TEEQFKSINV DPLDADEHSP FEFLQRGTNV QDQVQDCLLL QA
Length:1,142
Mass (Da):128,962
Last modified:June 10, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB1681C897D2E5967
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1142Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
EU482103 Genomic DNA Translation: ACA43044.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU482103 Genomic DNA Translation: ACA43044.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

Family and domain databases

InterProiView protein in InterPro
IPR015673, Enamelin
PANTHERiPTHR16784, PTHR16784, 1 hit
PfamiView protein in Pfam
PF15362, Enamelin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB2L7U8_9PRIM
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B2L7U8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: August 12, 2020
This is version 20 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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