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Protein

Glycogen [starch] synthase

Gene

GYS1

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.UniRule annotation

Catalytic activityi

UDP-alpha-D-glucose + ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationImported, Transferase
Biological processGlycogen biosynthesisUniRule annotation

Enzyme and pathway databases

UniPathwayi
UPA00164

Protein family/group databases

CAZyiGT3 Glycosyltransferase Family 3

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen [starch] synthaseUniRule annotation (EC:2.4.1.11UniRule annotation)
Gene namesi
Name:GYS1Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 10

Organism-specific databases

VGNCiVGNC:18670 GYS1

Subcellular locationi

PTM / Processingi

Proteomic databases

PeptideAtlasiB2L109

Expressioni

Gene expression databases

BgeeiENSECAG00000021428 Expressed in 3 organ(s), highest expression level in prefrontal cortex

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000019426

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 3 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3742 Eukaryota
COG0438 LUCA
GeneTreeiENSGT00390000018612
HOGENOMiHOG000160890
HOVERGENiHBG001960
KOiK00693
OMAiKVYFGRW
OrthoDBiEOG091G0304
TreeFamiTF300306

Family and domain databases

CDDicd03793 GT1_Glycogen_synthase_GSY2_lik, 1 hit
InterProiView protein in InterPro
IPR008631 Glycogen_synth
PANTHERiPTHR10176 PTHR10176, 1 hit
PfamiView protein in Pfam
PF05693 Glycogen_syn, 1 hit

Sequencei

Sequence statusi: Complete.

B2L109-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPLNRTLSMS SLPGLDDWED EFDLENTVLF EVAWEVANKV GGIYTVLQTK
60 70 80 90 100
AKVTGDEWGD NYYLVGPYTE QGVRTQVELL EPPTPALKRT LDSMNSKGCK
110 120 130 140 150
VYFGRWLIEG GPLVVLLDVG ASAWALERWK GELWDTCNIG VPWYDREAND
160 170 180 190 200
AVLFGFLTTW FLGEFLAQSE EKPHVVAHFH EWLAGIGLCL CRARRLPVAT
210 220 230 240 250
IFTTHATLLG RYLCAGAVDF YNNLENFNVD KEAGERQIYH RYCMERAAAH
260 270 280 290 300
CTHVFTTVSQ ITAIEAQHLL KRKPDIVTPN GLNVKKFSAM HEFQNLHAQS
310 320 330 340 350
KARIQEFVRG HFYGHLDFNL DKTLYFFIAG RYEFSNKGAD VFLEALARLN
360 370 380 390 400
YLLRVNGSEQ TVVAFFIMPA RTNNFNVETL KGQAVRKQLW DTANTVKEKF
410 420 430 440 450
GRKLYESLLV GSLPDMNKML DKEDFTMMKR AIFATQRQSF PPVCTHNMLD
460 470 480 490 500
DSSDPILTTI RRIGLFNSSA DRVKVIFHPE FLSSTSPLLP VDYEEFVRGC
510 520 530 540 550
HLGVFPSYYE PWGYTPAECT VMGIPSISTN LSGFGCFMEE HIADPSAYGI
560 570 580 590 600
YILDRRFRSL DDSCSQLTSF LYSFCQQSRR QRIIQRNRTE RLSDLLDWKY
610 620 630 640 650
LGRYYMSARH MALAKAFPEH FTYEPREADA TQGYRYPRPA SVPPSPSLSR
660 670 680 690 700
HSSPHQSEDE EEPRDVPPDE DSERYDEDEE AAKDRRNIRA PEWPRRASCT
710 720 730
SSTSGSKRGS VDTGPSSSLS TPSEPLSPAS SLGEERN
Length:737
Mass (Da):83,896
Last modified:June 10, 2008 - v1
Checksum:i5F01E0C31E482363
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU373801 mRNA Translation: ACB14276.1
AB522619 mRNA Translation: BAI79302.1
RefSeqiNP_001119597.2, NM_001126125.2
UniGeneiEca.16827

Genome annotation databases

EnsembliENSECAT00000023453; ENSECAP00000019426; ENSECAG00000021428
GeneIDi100054723
KEGGiecb:100054723

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU373801 mRNA Translation: ACB14276.1
AB522619 mRNA Translation: BAI79302.1
RefSeqiNP_001119597.2, NM_001126125.2
UniGeneiEca.16827

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9796.ENSECAP00000019426

Protein family/group databases

CAZyiGT3 Glycosyltransferase Family 3

Proteomic databases

PeptideAtlasiB2L109

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSECAT00000023453; ENSECAP00000019426; ENSECAG00000021428
GeneIDi100054723
KEGGiecb:100054723

Organism-specific databases

CTDi2997
VGNCiVGNC:18670 GYS1

Phylogenomic databases

eggNOGiKOG3742 Eukaryota
COG0438 LUCA
GeneTreeiENSGT00390000018612
HOGENOMiHOG000160890
HOVERGENiHBG001960
KOiK00693
OMAiKVYFGRW
OrthoDBiEOG091G0304
TreeFamiTF300306

Enzyme and pathway databases

UniPathwayi
UPA00164

Gene expression databases

BgeeiENSECAG00000021428 Expressed in 3 organ(s), highest expression level in prefrontal cortex

Family and domain databases

CDDicd03793 GT1_Glycogen_synthase_GSY2_lik, 1 hit
InterProiView protein in InterPro
IPR008631 Glycogen_synth
PANTHERiPTHR10176 PTHR10176, 1 hit
PfamiView protein in Pfam
PF05693 Glycogen_syn, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB2L109_HORSE
AccessioniPrimary (citable) accession number: B2L109
Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: September 12, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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