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Entry version 58 (29 Sep 2021)
Sequence version 1 (10 Jun 2008)
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Protein
Submitted name:

ATP-dependent exoDNAse (Exonuclease V) alpha subunit-helicase superfamily I member-like protein

Gene

Npun_AF036

Organism
Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionExonucleaseImported, HelicaseImported, Hydrolase, Nuclease
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ATP-dependent exoDNAse (Exonuclease V) alpha subunit-helicase superfamily I member-like proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Npun_AF036Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlasmid pNPUN01Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNostoc punctiforme (strain ATCC 29133 / PCC 73102)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri63737 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001191 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Plasmid pNPUN01

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini13 – 275TrwCInterPro annotationAdd BLAST263
Domaini1110 – 1235DUF3854InterPro annotationAdd BLAST126

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1272 – 1299DisorderedSequence analysisAdd BLAST28
Regioni2122 – 2142DisorderedSequence analysisAdd BLAST21

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili825 – 845Sequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CpcE/RpcE/PecE family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_231864_0_0_3

Database of Orthologous Groups

More...
OrthoDBi
10223at2

Database for complete collections of gene phylogenies

More...
PhylomeDBi
B2JAG8

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.300, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024, ARM-type_fold
IPR014059, Conjug_relaxase_N
IPR024385, DUF3854
IPR027417, P-loop_NTPase
IPR014862, TrwC

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12965, DUF3854, 1 hit
PF08751, TrwC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit
SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02686, relax_trwC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B2JAG8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLTAANVSSE MAVNYFVKNY YHQGKSLWSG QGALKLGLSG AIDDEEAFKN
60 70 80 90 100
VISGRSPQGR EQLNARALKP DERRAALDCT FSAPKSVSLM ALVGGDTRLI
110 120 130 140 150
DAHHQALKET LELIEQRYAY TRVTDNSGRH RVKTGNLVVA QFDHIESRDL
160 170 180 190 200
DPHLHTHCLL MNMTQTPDGR WLSLGNNEIF ANKKFLGMAY QSSLAREVQK
210 220 230 240 250
LGYEIEKSKH GQFDIKGFKF EDLEAFSKRR QQIIASFSAN STWAEREKIW
260 270 280 290 300
DNTRQRKQKL PESELLAFWK EEAAALGIRF VKAGEPRQEI PANEKSLAEV
310 320 330 340 350
LDLAIAHCSE RNVAFRQEDL EKFILEERLA TDIAATAALI REHQELIALP
360 370 380 390 400
GLTDQFTTMT AVRRELATID LMQQGQYKFC SISQREVVES HLENTLLNTG
410 420 430 440 450
QRQAVELAAT TSDQFIAWQG VAGAGKTFAL KELKAIAFNA GYTIKGFAPS
460 470 480 490 500
SSAAKVLSEE LEIQSETIAR LLVTEPKEIE PNQIWVVDEA GLLSAKDAHA
510 520 530 540 550
LLQRATLLQA RVILVGDTRQ LSAVEAGNPF KSLQQAGIKT AHLNESLRQK
560 570 580 590 600
NPQLKLAVNL IADGRIEAGF ERLEANGSIL QVDSFSKIEQ IANDYIVGTP
610 620 630 640 650
EQRLKTLVLA GTNTERLALT QAIRDKLKGE GTLGETATIT QLQTKNLTKV
660 670 680 690 700
QMRFAHNFEI GDVIMPTRDY KRRGLSKGKL YEVVGRTTDK LTLRSDDGQH
710 720 730 740 750
LEVDTAFDKA VYQRHQIEIA VGDRLQWKKN DRQLGRRNGQ EFTVTGIDLN
760 770 780 790 800
IVHIKYADER TERISLAQTQ NLDYALVSTT YSSQGKTADQ VLISADFTIG
810 820 830 840 850
QESFYVAASR ARHELKIYTE DPTRLVELAQ QSKAKDNALE LLRKQIQKST
860 870 880 890 900
IEQHQAITIN ISAPFEKPVL KQETTVSTPN VQPIVKSVAS SRTTSHDSSI
910 920 930 940 950
KVPKVLPVLK EIPNYNTVES VFSKPVLKSA APTEAFWTPH QSKDIPNFLE
960 970 980 990 1000
PKHWQEFEDS AIHPDIAAKN FESLQFNYAG GEHESWERLM VSEKLNRTNT
1010 1020 1030 1040 1050
GRLTEGLIRT YSHLDAGGWW CDAGVDPRTF ADLTPGDKPT LKRWGCYKPN
1060 1070 1080 1090 1100
QPRPKKDENN QIIEGKFIKY EHPPKVELSI FLLNVPDDIA ERIYSKHKAN
1110 1120 1130 1140 1150
PSDSDRQSGF WYCVWKHNIP CAIAEGAKKA ASLLSQGHAA IGLPGISAGY
1160 1170 1180 1190 1200
RTPKDEFGKK IGKSYLHEEL AIFATPSREI KFCFDYETKP KTKLNIERDI
1210 1220 1230 1240 1250
SVTGRLLQKL GARVKVVSLP GPSKGVDDFI VASGPLAYEK LSHEAMKLRD
1260 1270 1280 1290 1300
WQQHNQHSKV AAIEPPKLQL KESSLQQTSP NQPIGQTHDN QQQPNPDTVI
1310 1320 1330 1340 1350
NREDRGIINL SRETEQEFRA VRNQELSTHR KNSELRGSPA TEVERLLTAV
1360 1370 1380 1390 1400
SRDIECQEVL ELRAISTRIN PSSTDDWLRG QRATNFSRQV NPEDSAIIDG
1410 1420 1430 1440 1450
AASDVSFEQN GNAKRPTTEQ LLNAITENIQ QSIVDDALVE TLPQLTEQLY
1460 1470 1480 1490 1500
GYQQHLRRAR TRLDDFGAVI ASIEQQISSK RTVDVISDFI EQSVVESTLI
1510 1520 1530 1540 1550
TLLPQLVEQL SQVSQQLAHK TAIAQQSELS SSQKTVWAIA ENIEYLAVSS
1560 1570 1580 1590 1600
ALTEALPLLI KQLSPLRQQQ KGVRSRFDDL EAVITQIEQR LSSQRAIDAI
1610 1620 1630 1640 1650
TQNVEYSAVS SALTGTLPQL IKQFSPLRQQ LKKGIATFDK IFTAIEPLSQ
1660 1670 1680 1690 1700
RLDLQKTIDI IAEDIEQLAV ESALSETLPQ LIEQLSQHHQ HISGRITKFD
1710 1720 1730 1740 1750
DLETAISQSE QHLSTKKTVL SVLENIEQSL VESALAETLP RLIEQLSKTC
1760 1770 1780 1790 1800
QQQKALKPAF DKISTRIEHE IQYLSSQRTV DAIAQNIEQS LVESIITETL
1810 1820 1830 1840 1850
PQLIEQLSKT CQQHKGRTTF EGLGVAITQI EQRLDSQKTV DPIIENIEYS
1860 1870 1880 1890 1900
AVESALIETL PQLIEQLSQY HQQLKGGKTR FHGLEAAITQ IEQRLDSQRT
1910 1920 1930 1940 1950
ILSIAQSIEQ SLVESIITET LPQLIKQLSQ FSQQLKVGKT TFNQFQQLLD
1960 1970 1980 1990 2000
NEFVGYLTQK TRTSEHLALN AISDYVAQET VASYETVSAL SKLKELLGVS
2010 2020 2030 2040 2050
QSQTYTEFTT ALQKILDLTE KWGHHQNHSQ GNVQSLSIEV ETELLKESVK
2060 2070 2080 2090 2100
SHIKQIIHGL DIERLAALVM EVGKYVKGEK VTGAKVSELF TSVTTDAKAL
2110 2120 2130 2140
TFEQKMNIVR QLIKDDKPSI MKRLGINSPS PNDNEEHLRF RR
Length:2,142
Mass (Da):240,257
Last modified:June 10, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3DD8109C746B7A57
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP001038 Genomic DNA Translation: ACC84922.1

NCBI Reference Sequences

More...
RefSeqi
WP_012412944.1, NC_010631.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ACC84922; ACC84922; Npun_AF036

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
npu:Npun_AF036

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001038 Genomic DNA Translation: ACC84922.1
RefSeqiWP_012412944.1, NC_010631.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiACC84922; ACC84922; Npun_AF036
KEGGinpu:Npun_AF036

Phylogenomic databases

HOGENOMiCLU_231864_0_0_3
OrthoDBi10223at2
PhylomeDBiB2JAG8

Family and domain databases

Gene3Di3.40.50.300, 2 hits
InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR014059, Conjug_relaxase_N
IPR024385, DUF3854
IPR027417, P-loop_NTPase
IPR014862, TrwC
PfamiView protein in Pfam
PF12965, DUF3854, 1 hit
PF08751, TrwC, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit
SSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR02686, relax_trwC, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB2JAG8_NOSP7
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B2JAG8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: September 29, 2021
This is version 58 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

PlasmidImported, Reference proteomeImported
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