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Protein

Bifunctional protein PyrR

Gene

pyrR

Organism
Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.UniRule annotation
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.UniRule annotation

Catalytic activityi

UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciNPUN63737:G1GBR-2984-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bifunctional protein PyrRUniRule annotation
Including the following 2 domains:
Pyrimidine operon regulatory proteinUniRule annotation
Uracil phosphoribosyltransferaseUniRule annotation (EC:2.4.2.9UniRule annotation)
Short name:
UPRTaseUniRule annotation
Gene namesi
Name:pyrRUniRule annotation
Ordered Locus Names:Npun_F2899
OrganismiNostoc punctiforme (strain ATCC 29133 / PCC 73102)
Taxonomic identifieri63737 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
Proteomesi
  • UP000001191 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001392041 – 178Bifunctional protein PyrRAdd BLAST178

Proteomic databases

PRIDEiB2IWH8

Interactioni

Protein-protein interaction databases

STRINGi63737.Npun_F2899

Structurei

3D structure databases

ProteinModelPortaliB2IWH8
SMRiB2IWH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi99 – 111PRPP-bindingUniRule annotationAdd BLAST13

Sequence similaritiesi

Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UK1 Bacteria
COG2065 LUCA
HOGENOMiHOG000245770
KOiK02825
OMAiRISHEIL
OrthoDBiPOG091H02JM
PhylomeDBiB2IWH8

Family and domain databases

CDDicd06223 PRTases_typeI, 1 hit
HAMAPiMF_01219 PyrR, 1 hit
InterProiView protein in InterPro
IPR000836 PRibTrfase_dom
IPR029057 PRTase-like
IPR023050 PyrR
PfamiView protein in Pfam
PF00156 Pribosyltran, 1 hit
SUPFAMiSSF53271 SSF53271, 1 hit

Sequencei

Sequence statusi: Complete.

B2IWH8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAKVVEILS SEEIRRTLTR LASQIVERTR DLSQLVLLGI YTRGALLAEL
60 70 80 90 100
LARQIETLEG VAVSVGALDI TFYRDDLDTI GLRTPTKSEI PFDLTGKTVV
110 120 130 140 150
LVDDVIFKGR TIRAALNAVN DYGRPEVIRL AVLVDRGHRE LPIHPDFIGK
160 170
KLPTAKEEVV KVYLQNYDGR DAVELIGD
Length:178
Mass (Da):19,796
Last modified:June 10, 2008 - v1
Checksum:iFA37230F735BC46B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001037 Genomic DNA Translation: ACC81432.1
RefSeqiWP_012409423.1, NC_010628.1

Genome annotation databases

EnsemblBacteriaiACC81432; ACC81432; Npun_F2899
KEGGinpu:Npun_F2899

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001037 Genomic DNA Translation: ACC81432.1
RefSeqiWP_012409423.1, NC_010628.1

3D structure databases

ProteinModelPortaliB2IWH8
SMRiB2IWH8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi63737.Npun_F2899

Proteomic databases

PRIDEiB2IWH8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACC81432; ACC81432; Npun_F2899
KEGGinpu:Npun_F2899

Phylogenomic databases

eggNOGiENOG4108UK1 Bacteria
COG2065 LUCA
HOGENOMiHOG000245770
KOiK02825
OMAiRISHEIL
OrthoDBiPOG091H02JM
PhylomeDBiB2IWH8

Enzyme and pathway databases

BioCyciNPUN63737:G1GBR-2984-MONOMER

Family and domain databases

CDDicd06223 PRTases_typeI, 1 hit
HAMAPiMF_01219 PyrR, 1 hit
InterProiView protein in InterPro
IPR000836 PRibTrfase_dom
IPR029057 PRTase-like
IPR023050 PyrR
PfamiView protein in Pfam
PF00156 Pribosyltran, 1 hit
SUPFAMiSSF53271 SSF53271, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPYRR_NOSP7
AccessioniPrimary (citable) accession number: B2IWH8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 10, 2008
Last modified: November 7, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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