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UniProtKB - B2IRN2 (B2IRN2_STRPS)
Protein
Submitted name:
Lantibiotic efflux protein
Gene
SPCG_0147
Organism
Streptococcus pneumoniae (strain CGSP14)
Status
Functioni
GO - Molecular functioni
- transmembrane transporter activity Source: InterPro
Keywordsi
Biological process | TransportARBA annotation |
Protein family/group databases
TCDBi | 2.A.1.47.3, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Submitted name: Lantibiotic efflux proteinImported |
Gene namesi | Ordered Locus Names:SPCG_0147Imported |
Organismi | Streptococcus pneumoniae (strain CGSP14)Imported |
Taxonomic identifieri | 516950 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 9 – 31 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 43 – 65 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 86 – 112 | HelicalSequence analysisAdd BLAST | 27 | |
Transmembranei | 160 – 189 | HelicalSequence analysisAdd BLAST | 30 | |
Transmembranei | 237 – 257 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 269 – 295 | HelicalSequence analysisAdd BLAST | 27 | |
Transmembranei | 389 – 411 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 9 – 418 | MFSInterPro annotationAdd BLAST | 410 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
HOGENOMi | CLU_051151_0_0_9 |
OMAi | PKWVEKE |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR036259, MFS_trans_sf IPR010290, TM_effector |
Pfami | View protein in Pfam PF05977, MFS_3, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
B2IRN2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKKILNNKLY MKVLVSDLIS NFGDTLYFIA LMTYVTEIKS SNLAISIVNI
60 70 80 90 100
SETIPILFTI FFGIIADRTL NKVGMIIKTL WIRTILYLLV AVVMNFKESI
110 120 130 140 150
LVVILASIVN LISDTLGQFE NGLFYPISNR IVKKSDREET MAFRQTATST
160 170 180 190 200
MNIVNQSLGA FLITFLSFFH LALINSLTFA ISLLITLAIK SQINNFYIDK
210 220 230 240 250
TPSTKVSKVD FKATFSDIIS NLKLSLKHLF SLTNMKTVLL VIPILNGSLA
260 270 280 290 300
IIIPLAVVNL SKSSALTIIS SATTISVLGI STVSGGILGG TLILISKKFK
310 320 330 340 350
NLSIENLLKM NLMTILLSFI AFYYQNIYFI VLTLFLSSVF VSALNPKIGA
360 370 380 390 400
IIFNNLDETK LATIFGGMVT YFQLGDVVSR LLFSTLVIYL SYTYIAVIYM
410
ILVLIVAIYT FRRVQTTS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001033 Genomic DNA Translation: ACB89399.1 |
RefSeqi | WP_000722643.1, NC_010582.1 |
Genome annotation databases
EnsemblBacteriai | ACB89399; ACB89399; SPCG_0147 |
KEGGi | spw:SPCG_0147 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001033 Genomic DNA Translation: ACB89399.1 |
RefSeqi | WP_000722643.1, NC_010582.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
TCDBi | 2.A.1.47.3, the major facilitator superfamily (mfs) |
Genome annotation databases
EnsemblBacteriai | ACB89399; ACB89399; SPCG_0147 |
KEGGi | spw:SPCG_0147 |
Phylogenomic databases
HOGENOMi | CLU_051151_0_0_9 |
OMAi | PKWVEKE |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR036259, MFS_trans_sf IPR010290, TM_effector |
Pfami | View protein in Pfam PF05977, MFS_3, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | B2IRN2_STRPS | |
Accessioni | B2IRN2Primary (citable) accession number: B2IRN2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 10, 2008 |
Last sequence update: | June 10, 2008 | |
Last modified: | September 29, 2021 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |