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Protein
Submitted name:

Carbonyl reductase 3

Gene

Cbr3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • 3-keto sterol reductase activity Source: RGD
  • carbonyl reductase (NADPH) activity Source: RGD
  • NADPH binding Source: Ensembl

GO - Biological processi

  • cognition Source: Ensembl
  • phylloquinone catabolic process Source: RGD

Enzyme and pathway databases

BRENDAi1.1.1.184 5301
ReactomeiR-RNO-211945 Phase I - Functionalization of compounds

Names & Taxonomyi

Protein namesi
Submitted name:
Carbonyl reductase 3Imported
Submitted name:
Carbonyl reductase 3 (Predicted)Imported
Gene namesi
Name:Cbr3Imported
Synonyms:Cbr3_predictedImported
ORF Names:rCG_53069Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 11

Organism-specific databases

RGDi1309728 Cbr3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000001701

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000002310

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1208 Eukaryota
COG1028 LUCA
GeneTreeiENSGT00510000046499
HOVERGENiHBG001909
KOiK00084
OMAiNEMDTNS
OrthoDBiEOG091G0V7L
TreeFamiTF329359

Family and domain databases

InterProiView protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR020904 Sc_DH/Rdtase_CS
IPR002347 SDR_fam
PfamiView protein in Pfam
PF00106 adh_short, 1 hit
PRINTSiPR00081 GDHRDH
PR00080 SDRFAMILY
SUPFAMiSSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00061 ADH_SHORT, 1 hit

Sequencei

Sequence statusi: Complete.

B2GV72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSCSRVALV TGANKGIGFA ITRDLCRKFS GDVVLTARDE ARGRAAVKQL
60 70 80 90 100
QAEGLSPRFH QLDIDNPQSI RALRDFLRKE YGGLNVLVNN AGIAFRMDDP
110 120 130 140 150
TPFDVQAEVT LKTNFFATRN VCTELLPIMK PHGRVVNVSS LQGLKALENC
160 170 180 190 200
SEDLQERFRC DTLTEGDLVD LMKKFVEDTK NEVHEREGWP DSAYGVSKLG
210 220 230 240 250
VTVLTRILAR QLDEKRKADR ILLNACCPGW VKTDMARDQG SRTVEEGAET
260 270
PVYLALLPPD ATEPHGQLVR DKVVQTW
Length:277
Mass (Da):30,841
Last modified:June 10, 2008 - v1
Checksum:i05DBA2BCCD985EB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07033657 Genomic DNA No translation available.
BC166553 mRNA Translation: AAI66553.1
CH474083 Genomic DNA Translation: EDL76737.1
RefSeqiNP_001100580.1, NM_001107110.1
UniGeneiRn.8624

Genome annotation databases

EnsembliENSRNOT00000002310; ENSRNOP00000002310; ENSRNOG00000001701
GeneIDi304078
KEGGirno:304078
UCSCiRGD:1309728 rat

Similar proteinsi

Entry informationi

Entry nameiB2GV72_RAT
AccessioniPrimary (citable) accession number: B2GV72
Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: July 18, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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