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UniProtKB - B2GV72 (B2GV72_RAT)
Protein
Carbonyl reductase (NADPH)
Gene
Cbr3
Organism
Rattus norvegicus (Rat)
Status
Functioni
Catalytic activityi
- EC:1.1.1.184ARBA annotation
GO - Molecular functioni
- 3-keto sterol reductase activity Source: RGD
- carbonyl reductase (NADPH) activity Source: RGD
- NADPH binding Source: RGD
- oxidoreductase activity Source: GO_Central
GO - Biological processi
- cognition Source: RGD
- phylloquinone catabolic process Source: RGD
Keywordsi
Molecular function | OxidoreductaseARBA annotation |
Enzyme and pathway databases
BRENDAi | 1.1.1.184, 5301 |
Reactomei | R-RNO-211945, Phase I - Functionalization of compounds |
Names & Taxonomyi
Protein namesi | |
Gene namesi | ORF Names:rCG_53069Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1309728, Cbr3 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000001701, Expressed in stomach and 21 other tissues |
Structurei
Family & Domainsi
Sequence similaritiesi
Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG1208, Eukaryota |
GeneTreei | ENSGT00940000162541 |
HOGENOMi | CLU_010194_9_0_1 |
OMAi | ALRINCA |
OrthoDBi | 1259665at2759 |
TreeFami | TF329359 |
Family and domain databases
CDDi | cd05324, carb_red_PTCR-like_SDR_c, 1 hit |
InterProi | View protein in InterPro IPR045313, CBR1-like IPR036291, NAD(P)-bd_dom_sf IPR020904, Sc_DH/Rdtase_CS IPR002347, SDR_fam |
Pfami | View protein in Pfam PF00106, adh_short, 1 hit |
PRINTSi | PR00081, GDHRDH PR00080, SDRFAMILY |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00061, ADH_SHORT, 1 hit |
i Sequence
Sequence statusi: Complete.
B2GV72-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSCSRVALV TGANKGIGFA ITRDLCRKFS GDVVLTARDE ARGRAAVKQL
60 70 80 90 100
QAEGLSPRFH QLDIDNPQSI RALRDFLRKE YGGLNVLVNN AGIAFRMDDP
110 120 130 140 150
TPFDVQAEVT LKTNFFATRN VCTELLPIMK PHGRVVNVSS LQGLKALENC
160 170 180 190 200
SEDLQERFRC DTLTEGDLVD LMKKFVEDTK NEVHEREGWP DSAYGVSKLG
210 220 230 240 250
VTVLTRILAR QLDEKRKADR ILLNACCPGW VKTDMARDQG SRTVEEGAET
260 270
PVYLALLPPD ATEPHGQLVR DKVVQTW
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07033657 Genomic DNA No translation available. BC166553 mRNA Translation: AAI66553.1 CH474083 Genomic DNA Translation: EDL76737.1 |
RefSeqi | NP_001100580.1, NM_001107110.1 |
Genome annotation databases
Ensembli | ENSRNOT00000002310; ENSRNOP00000002310; ENSRNOG00000001701 |
GeneIDi | 304078 |
KEGGi | rno:304078 |
UCSCi | RGD:1309728, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07033657 Genomic DNA No translation available. BC166553 mRNA Translation: AAI66553.1 CH474083 Genomic DNA Translation: EDL76737.1 |
RefSeqi | NP_001100580.1, NM_001107110.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000002310 |
Genome annotation databases
Ensembli | ENSRNOT00000002310; ENSRNOP00000002310; ENSRNOG00000001701 |
GeneIDi | 304078 |
KEGGi | rno:304078 |
UCSCi | RGD:1309728, rat |
Organism-specific databases
CTDi | 874 |
RGDi | 1309728, Cbr3 |
Phylogenomic databases
eggNOGi | KOG1208, Eukaryota |
GeneTreei | ENSGT00940000162541 |
HOGENOMi | CLU_010194_9_0_1 |
OMAi | ALRINCA |
OrthoDBi | 1259665at2759 |
TreeFami | TF329359 |
Enzyme and pathway databases
BRENDAi | 1.1.1.184, 5301 |
Reactomei | R-RNO-211945, Phase I - Functionalization of compounds |
Gene expression databases
Bgeei | ENSRNOG00000001701, Expressed in stomach and 21 other tissues |
Family and domain databases
CDDi | cd05324, carb_red_PTCR-like_SDR_c, 1 hit |
InterProi | View protein in InterPro IPR045313, CBR1-like IPR036291, NAD(P)-bd_dom_sf IPR020904, Sc_DH/Rdtase_CS IPR002347, SDR_fam |
Pfami | View protein in Pfam PF00106, adh_short, 1 hit |
PRINTSi | PR00081, GDHRDH PR00080, SDRFAMILY |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00061, ADH_SHORT, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | B2GV72_RAT | |
Accessioni | B2GV72Primary (citable) accession number: B2GV72 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 10, 2008 |
Last sequence update: | June 10, 2008 | |
Last modified: | January 19, 2022 | |
This is version 106 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |