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Protein
Submitted name:

B-cell CLL/lymphoma 6

Gene

Bcl6

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
B-cell CLL/lymphoma 6Imported
Submitted name:
B-cell leukemia/lymphoma 6 (Predicted)Imported
Gene namesi
Name:Bcl6Imported
Synonyms:Bcl6_predictedImported
ORF Names:rCG_36575Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 11

Organism-specific databases

RGDi1309345 Bcl6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000001843 Expressed in 9 organ(s), highest expression level in skeletal muscle tissue

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000002522

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 99BTBInterPro annotationAdd BLAST68
Domaini519 – 547C2H2-typeInterPro annotationAdd BLAST29
Domaini547 – 574C2H2-typeInterPro annotationAdd BLAST28
Domaini575 – 602C2H2-typeInterPro annotationAdd BLAST28
Domaini603 – 630C2H2-typeInterPro annotationAdd BLAST28
Domaini631 – 658C2H2-typeInterPro annotationAdd BLAST28
Domaini659 – 682C2H2-typeInterPro annotationAdd BLAST24

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00930000150977
HOGENOMiHOG000001556
HOVERGENiHBG004831
KOiK15618
OMAiTEMCLHT
OrthoDBiEOG091G025U
TreeFamiTF330912

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00651 BTB, 1 hit
PF00096 zf-C2H2, 4 hits
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 6 hits
SUPFAMiSSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 6 hits
PS50157 ZINC_FINGER_C2H2_2, 6 hits

Sequencei

Sequence statusi: Complete.

B2GUV8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASPADSCIQ FTRHASDVLL NLNRLRSRDI LTDVVIVVSR EQFRAHKTVL
60 70 80 90 100
MACSGLFYSI FTDQLKCNLS VINLDPEISP EGFCILLDFM YTSRLNLREG
110 120 130 140 150
NIMAVMATAM YLQMEHVVDT CRKFIKASEA EMAPALKPPR EEFLNSRMLM
160 170 180 190 200
PHDVMAYRGR EVVENNMPLR NTPGCESRAF APPLYSGLST PPASYPMYSH
210 220 230 240 250
LPLSSFLFSD EELRDAPRMP VANPFPKERA LPCDSARPVP NEYSRPTMEV
260 270 280 290 300
SPSLCHSNIY SPKEAVPEEA RSDIHYSVTE GPKPAAPSAR HASYFPCDKA
310 320 330 340 350
SKEEERPSSE DEIALHFEPP NAPLNRKGLV SPQSPQKSDC QPNSPTESSS
360 370 380 390 400
SKNACILQAS GSPPAKSPTD PKACNWKKYK FIVLNSLNQN AKPEGSEQAE
410 420 430 440 450
LGRLSPRAYP APPACQPPME PANLDLQSPT KLSASGEDST IPQASRLNNI
460 470 480 490 500
VNRSLAGSPR SSSESHSPLY MHPPKCTSCG SQSPQHTEMC LHTAGPTFPE
510 520 530 540 550
EMGETQSEYS DSSCENGAFF CNECDCRFSE EASLKRHTLQ THSDKPYKCD
560 570 580 590 600
RCQASFRYKG NLASHKTVHT GEKPYRCNIC GAQFNRPANL KTHTRIHSGE
610 620 630 640 650
KPYKCETCGA RFVQVAHLRA HVLIHTGEKP YPCEICGTRF RHLQTLKSHL
660 670 680 690 700
RIHTGEKPYH CEKCNLHFRH KSQLRLHLRQ KHGAITNTKV QYRVSAADLP

PELPKAC
Length:707
Mass (Da):78,865
Last modified:June 10, 2008 - v1
Checksum:i81967D3F2087EB1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07034589 Genomic DNA No translation available.
BC166425 mRNA Translation: AAI66425.1
CH473999 Genomic DNA Translation: EDL78099.1
RefSeqiNP_001100554.1, NM_001107084.1
UniGeneiRn.20571

Genome annotation databases

EnsembliENSRNOT00000002522; ENSRNOP00000002522; ENSRNOG00000001843
GeneIDi303836
KEGGirno:303836
UCSCiRGD:1309345 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07034589 Genomic DNA No translation available.
BC166425 mRNA Translation: AAI66425.1
CH473999 Genomic DNA Translation: EDL78099.1
RefSeqiNP_001100554.1, NM_001107084.1
UniGeneiRn.20571

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000002522

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000002522; ENSRNOP00000002522; ENSRNOG00000001843
GeneIDi303836
KEGGirno:303836
UCSCiRGD:1309345 rat

Organism-specific databases

CTDi604
RGDi1309345 Bcl6

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00930000150977
HOGENOMiHOG000001556
HOVERGENiHBG004831
KOiK15618
OMAiTEMCLHT
OrthoDBiEOG091G025U
TreeFamiTF330912

Gene expression databases

BgeeiENSRNOG00000001843 Expressed in 9 organ(s), highest expression level in skeletal muscle tissue

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00651 BTB, 1 hit
PF00096 zf-C2H2, 4 hits
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 6 hits
SUPFAMiSSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 6 hits
PS50157 ZINC_FINGER_C2H2_2, 6 hits
ProtoNetiSearch...

Entry informationi

Entry nameiB2GUV8_RAT
AccessioniPrimary (citable) accession number: B2GUV8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: November 7, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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