UniProtKB - B2GT34 (B2GT34_DANRE)
Protein
Citrate synthase
Gene
cs
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
: tricarboxylic acid cycle Pathwayi
This protein is involved in step 1 of the subpathway that synthesizes isocitrate from oxaloacetate.ARBA annotationProteins known to be involved in the 2 steps of the subpathway in this organism are:
- Citrate synthase (cs), Citrate synthase (cs), Citrate synthase, mitochondrial (cs)
- Aconitate hydratase, mitochondrial (aco2), Aconitate hydratase, mitochondrial (aco2), Aconitate hydratase, mitochondrial (aco2)
View all proteins of this organism that are known to be involved in the subpathway that synthesizes isocitrate from oxaloacetate, the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.
GO - Molecular functioni
- citrate (Si)-synthase activity Source: InterPro
GO - Biological processi
- citrate metabolic process Source: InterPro
- tricarboxylic acid cycle Source: UniProtKB-UniPathway
Keywordsi
Molecular function | TransferaseUniRule annotationARBA annotation |
Enzyme and pathway databases
UniPathwayi | UPA00223;UER00717 |
Names & Taxonomyi
Protein namesi | Recommended name: Citrate synthaseUniRule annotation |
Gene namesi | Name:csImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Organism-specific databases
ZFINi | ZDB-GENE-030131-1058, cs |
Subcellular locationi
Mitochondrion
- Mitochondrion matrix ARBA annotation
Mitochondrion
- mitochondrial matrix Source: UniProtKB-SubCell
Keywords - Cellular componenti
MitochondrionARBA annotationInteractioni
Subunit structurei
Homodimer.
ARBA annotationFamily & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transit peptideARBA annotationPhylogenomic databases
OrthoDBi | 1131452at2759 |
PhylomeDBi | B2GT34 |
Family and domain databases
Gene3Di | 1.10.230.10, 1 hit 1.10.580.10, 1 hit |
InterProi | View protein in InterPro IPR016142, Citrate_synth-like_lrg_a-sub IPR016143, Citrate_synth-like_sm_a-sub IPR002020, Citrate_synthase IPR019810, Citrate_synthase_AS IPR010109, Citrate_synthase_euk IPR036969, Citrate_synthase_sf |
PANTHERi | PTHR11739, PTHR11739, 1 hit |
Pfami | View protein in Pfam PF00285, Citrate_synt, 1 hit |
PRINTSi | PR00143, CITRTSNTHASE |
SUPFAMi | SSF48256, SSF48256, 1 hit |
TIGRFAMsi | TIGR01793, cit_synth_euk, 1 hit |
PROSITEi | View protein in PROSITE PS00480, CITRATE_SYNTHASE, 1 hit |
i Sequence
Sequence statusi: Complete.
B2GT34-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSFLSISRLA PRLLSSKNAA CVVVAARNAS ASTNLKDVLS DLVPKEQSRI
60 70 80 90 100
KNFKQQYGKT SIGQITVDMV YGGMRGVKGL VYETSVLDPD EGIRFRGYSI
110 120 130 140 150
PECQQLLPKA PGGEEPLPEG LFWLLVTGQV PTEEQVSWLS KEWAKRAALP
160 170 180 190 200
SHVVTMLDNF PTNLHPMSQF SAAITALNSE SSFARAYSEG VNKAKYWEFV
210 220 230 240 250
YEDSMDLIAK LPCVAAKIYR NLYREGSSIG AIDSNLDWSH NFTNMLGYTE
260 270 280 290 300
PQFTELMRLY LTIHSDHEGG NVSAHTSHLV GSALSDPYLS FSAAMNGLAG
310 320 330 340 350
PLHGLANQEV LVWLTALQKE LGGEVSDEKM RDYIWNTLKS GRVVPGYGHA
360 370 380 390 400
VLRKTDPRYT CQREFALKHL PNDPMFKLVA QLYKIVPNVL LEQGKAKNPW
410 420 430 440 450
PNVDAHSGVL LQYYGMTEMN YYTVLFGVSR ALGVLAQLVW SRALGFPLER
460
PKSMSTDGLM ALVGAKSG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC165743 mRNA Translation: AAI65743.1 |
RefSeqi | NP_955892.1, NM_199598.1 |
Genome annotation databases
GeneIDi | 322339 |
KEGGi | dre:322339 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC165743 mRNA Translation: AAI65743.1 |
RefSeqi | NP_955892.1, NM_199598.1 |
3D structure databases
SMRi | B2GT34 |
ModBasei | Search... |
Genome annotation databases
GeneIDi | 322339 |
KEGGi | dre:322339 |
Organism-specific databases
CTDi | 1431 |
ZFINi | ZDB-GENE-030131-1058, cs |
Phylogenomic databases
OrthoDBi | 1131452at2759 |
PhylomeDBi | B2GT34 |
Enzyme and pathway databases
UniPathwayi | UPA00223;UER00717 |
Family and domain databases
Gene3Di | 1.10.230.10, 1 hit 1.10.580.10, 1 hit |
InterProi | View protein in InterPro IPR016142, Citrate_synth-like_lrg_a-sub IPR016143, Citrate_synth-like_sm_a-sub IPR002020, Citrate_synthase IPR019810, Citrate_synthase_AS IPR010109, Citrate_synthase_euk IPR036969, Citrate_synthase_sf |
PANTHERi | PTHR11739, PTHR11739, 1 hit |
Pfami | View protein in Pfam PF00285, Citrate_synt, 1 hit |
PRINTSi | PR00143, CITRTSNTHASE |
SUPFAMi | SSF48256, SSF48256, 1 hit |
TIGRFAMsi | TIGR01793, cit_synth_euk, 1 hit |
PROSITEi | View protein in PROSITE PS00480, CITRATE_SYNTHASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B2GT34_DANRE | |
Accessioni | B2GT34Primary (citable) accession number: B2GT34 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 19, 2014 |
Last sequence update: | February 19, 2014 | |
Last modified: | December 2, 2020 | |
This is version 32 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |