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Entry version 41 (31 Jul 2019)
Sequence version 1 (19 Feb 2014)
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Protein
Submitted name:

Chaf1a protein

Gene

chaf1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Chaf1a proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:chaf1aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-030131-5366 chaf1a

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000062152 Expressed in 28 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
B2GSW9 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini18 – 198CAF1-p150_NInterPro annotationAdd BLAST181
Domaini581 – 852CAF1-p150_C2InterPro annotationAdd BLAST272

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 353DisorderedSequence analysisAdd BLAST353
Regioni423 – 466DisorderedSequence analysisAdd BLAST44
Regioni513 – 579DisorderedSequence analysisAdd BLAST67
Regioni749 – 863DisorderedSequence analysisAdd BLAST115

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi41 – 55PolyampholyteSequence analysisAdd BLAST15
Compositional biasi112 – 126PolarSequence analysisAdd BLAST15
Compositional biasi137 – 153PolarSequence analysisAdd BLAST17
Compositional biasi177 – 196AcidicSequence analysisAdd BLAST20
Compositional biasi200 – 243PolarSequence analysisAdd BLAST44
Compositional biasi248 – 353PolyampholyteSequence analysisAdd BLAST106
Compositional biasi513 – 547AcidicSequence analysisAdd BLAST35
Compositional biasi749 – 785PolarSequence analysisAdd BLAST37
Compositional biasi802 – 817AcidicSequence analysisAdd BLAST16
Compositional biasi820 – 847PolarSequence analysisAdd BLAST28

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410ISTP Eukaryota
ENOG410ZXI9 LUCA

KEGG Orthology (KO)

More...
KOi
K10750

Identification of Orthologs from Complete Genome Data

More...
OMAi
QQFTACL

Database of Orthologous Groups

More...
OrthoDBi
1362011at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
B2GSW9

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR029105 CAF1-p150_C2
IPR029091 CAF1_asu_N
IPR022043 CAF1A

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15539 CAF1-p150_C2, 1 hit
PF15557 CAF1-p150_N, 1 hit
PF12253 CAF1A, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B2GSW9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVVVMLAAEE PLASTPRRDM DCVGKANTNK KLVQARLPFK RLNPEPKECN
60 70 80 90 100
EPKRTKGPVA PKCSEPSDQE NDQDSSSISH HGPALVNGRG PLDCFMSRRK
110 120 130 140 150
RSPLRSAPEA TIDLTEDSND SAKQQPAPPI AATCPLSEEK TKTSEGTTEP
160 170 180 190 200
TIPLTEEETE KDEAEDVDAL PLLDITQDSD TEEEEEEEEE EEEQQQEAEV
210 220 230 240 250
SHGNESVLST GSTSSASVIA SSPEPSKSAP TTPASTSRIN AANKVKRRSL
260 270 280 290 300
KSVQEQEEKQ RQRDEKERLK QEAKAAKEKK KEEARKMKEE KEREKKEKKE
310 320 330 340 350
KDEKERREKK ERDEKEKADK LKAKEEQRQM KIEAKLEEKR KKEEEKRLKE
360 370 380 390 400
EKDRIKAEKA EITRFLQKPK TQLAPKTLAS ACGKFAPFEI KAHMSLAPLT
410 420 430 440 450
RVQCEDSVLE DLDRYLAQPD STLNGLKDWT GHKPRSSGPT RPRHSAQGDC
460 470 480 490 500
VVITESQKAD DGPDRSRYGR MKLLHFHDNY RPAYWGTWSK KSTHISPRCP
510 520 530 540 550
LRLDKDLLDY EVDSDEEWEE EEPGESLSHS EGDDDDEAGE DDDDDDGFFV
560 570 580 590 600
PHGYLSEGEG ALEDEEGGDP EKQKVRQRMK AREWENELMS KGKVKVLEAV
610 620 630 640 650
VRGCFWEGEK PLPDFLQPYA VCMLEPLSKD EASTPEQDAS RQQRNEKLLT
660 670 680 690 700
MLLPLLHGNV NSNKVIITEF LEFCRQQTSS PTESLLNTTE SIPPRIHVRR
710 720 730 740 750
IIKENAVYEK RSTFKRCCWY VHADVLARYS QEALPVPCQW SYLTSGANVT
760 770 780 790 800
RDEHSGSQGN SPTTNSSTTP SNKRKSASSH SITKYMKKCG ESEQTEAMET
810 820 830 840 850
DGFQADTEDD EDDDCIIIGE QSGSSEQDIN TSLPQTDRET EPMDTSASET
860
AALALPCPTP ATA
Length:863
Mass (Da):97,223
Last modified:February 19, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i61C1251E909E9E9F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC165675 mRNA Translation: AAI65675.1

NCBI Reference Sequences

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RefSeqi
NP_001038478.2, NM_001045013.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
563212

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:563212

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC165675 mRNA Translation: AAI65675.1
RefSeqiNP_001038478.2, NM_001045013.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi563212
KEGGidre:563212

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10036
ZFINiZDB-GENE-030131-5366 chaf1a

Phylogenomic databases

eggNOGiENOG410ISTP Eukaryota
ENOG410ZXI9 LUCA
KOiK10750
OMAiQQFTACL
OrthoDBi1362011at2759
PhylomeDBiB2GSW9

Gene expression databases

BgeeiENSDARG00000062152 Expressed in 28 organ(s), highest expression level in testis
ExpressionAtlasiB2GSW9 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR029105 CAF1-p150_C2
IPR029091 CAF1_asu_N
IPR022043 CAF1A
PfamiView protein in Pfam
PF15539 CAF1-p150_C2, 1 hit
PF15557 CAF1-p150_N, 1 hit
PF12253 CAF1A, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB2GSW9_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B2GSW9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 19, 2014
Last sequence update: February 19, 2014
Last modified: July 31, 2019
This is version 41 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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