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Protein

Urease subunit gamma

Gene

ureA

Organism
Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Urea + H2O = CO2 + 2 NH3.UniRule annotation

Pathwayi: urea degradation

This protein is involved in step 1 of the subpathway that synthesizes CO(2) and NH(3) from urea (urease route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Urease subunit gamma (ureA), Urease subunit beta (ureB), Urease subunit alpha (ureC)
This subpathway is part of the pathway urea degradation, which is itself part of Nitrogen metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CO(2) and NH(3) from urea (urease route), the pathway urea degradation and in Nitrogen metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciKRHI378753:G1G2M-2184-MONOMER
UniPathwayi
UPA00258;UER00370

Names & Taxonomyi

Protein namesi
Recommended name:
Urease subunit gammaUniRule annotation (EC:3.5.1.5UniRule annotation)
Alternative name(s):
Urea amidohydrolase subunit gammaUniRule annotation
Gene namesi
Name:ureAUniRule annotation
Ordered Locus Names:KRH_21730
OrganismiKocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201)
Taxonomic identifieri378753 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrococcaceaeKocuria
Proteomesi
  • UP000008838 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001998661 – 100Urease subunit gammaAdd BLAST100

Interactioni

Subunit structurei

Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.UniRule annotation

Protein-protein interaction databases

STRINGi378753.KRH_21730

Structurei

3D structure databases

SMRiB2GI08
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the urease gamma subunit family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108YZ9 Bacteria
COG0831 LUCA
HOGENOMiHOG000075053
KOiK01430
OMAiMIHEVQV
OrthoDBiPOG091H09TI

Family and domain databases

CDDicd00390 Urease_gamma, 1 hit
Gene3Di3.30.280.10, 1 hit
HAMAPiMF_00739 Urease_gamma, 1 hit
InterProiView protein in InterPro
IPR012010 Urease_gamma
IPR002026 Urease_gamma/gamma-beta_su
IPR036463 Urease_gamma_sf
PANTHERiPTHR45301 PTHR45301, 1 hit
PfamiView protein in Pfam
PF00547 Urease_gamma, 1 hit
PIRSFiPIRSF001223 Urease_gamma, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002319 Urease_gamma_reg, 1 hit
SUPFAMiSSF54111 SSF54111, 1 hit
TIGRFAMsiTIGR00193 urease_gam, 1 hit

Sequencei

Sequence statusi: Complete.

B2GI08-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHLQPKDQEK LLVVVAADLA RRRQARGLKL NHPEAIAIIT YELLEGARDG
60 70 80 90 100
RTVAELMSWG STILSREDVM EGVPEMIPDV QVEATFPDGT KLVTVHDPIR
Length:100
Mass (Da):11,155
Last modified:June 10, 2008 - v1
Checksum:i4C9433AE5E9CDD90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009152 Genomic DNA Translation: BAG30520.1
RefSeqiWP_012399241.1, NC_010617.1

Genome annotation databases

EnsemblBacteriaiBAG30520; BAG30520; KRH_21730
GeneIDi35828173
KEGGikrh:KRH_21730

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009152 Genomic DNA Translation: BAG30520.1
RefSeqiWP_012399241.1, NC_010617.1

3D structure databases

SMRiB2GI08
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi378753.KRH_21730

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAG30520; BAG30520; KRH_21730
GeneIDi35828173
KEGGikrh:KRH_21730

Phylogenomic databases

eggNOGiENOG4108YZ9 Bacteria
COG0831 LUCA
HOGENOMiHOG000075053
KOiK01430
OMAiMIHEVQV
OrthoDBiPOG091H09TI

Enzyme and pathway databases

UniPathwayi
UPA00258;UER00370

BioCyciKRHI378753:G1G2M-2184-MONOMER

Family and domain databases

CDDicd00390 Urease_gamma, 1 hit
Gene3Di3.30.280.10, 1 hit
HAMAPiMF_00739 Urease_gamma, 1 hit
InterProiView protein in InterPro
IPR012010 Urease_gamma
IPR002026 Urease_gamma/gamma-beta_su
IPR036463 Urease_gamma_sf
PANTHERiPTHR45301 PTHR45301, 1 hit
PfamiView protein in Pfam
PF00547 Urease_gamma, 1 hit
PIRSFiPIRSF001223 Urease_gamma, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002319 Urease_gamma_reg, 1 hit
SUPFAMiSSF54111 SSF54111, 1 hit
TIGRFAMsiTIGR00193 urease_gam, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiURE3_KOCRD
AccessioniPrimary (citable) accession number: B2GI08
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 10, 2008
Last modified: October 10, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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Main funding by: National Institutes of Health

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