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Protein

Cation/acetate symporter ActP

Gene

actP

Organism
Escherichia coli (strain K12 / DH10B)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transports acetate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processIon transport, Sodium transport, Symport, Transport
LigandSodium

Names & Taxonomyi

Protein namesi
Recommended name:
Cation/acetate symporter ActPUniRule annotation
Alternative name(s):
Acetate permeaseUniRule annotation
Acetate transporter ActPUniRule annotation
Gene namesi
Name:actPUniRule annotation
Ordered Locus Names:ECDH10B_4257
OrganismiEscherichia coli (strain K12 / DH10B)
Taxonomic identifieri316385 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 53HelicalUniRule annotationAdd BLAST21
Transmembranei77 – 97HelicalUniRule annotationAdd BLAST21
Transmembranei103 – 123HelicalUniRule annotationAdd BLAST21
Transmembranei148 – 168HelicalUniRule annotationAdd BLAST21
Transmembranei183 – 203HelicalUniRule annotationAdd BLAST21
Transmembranei206 – 226HelicalUniRule annotationAdd BLAST21
Transmembranei262 – 282HelicalUniRule annotationAdd BLAST21
Transmembranei303 – 323HelicalUniRule annotationAdd BLAST21
Transmembranei355 – 375HelicalUniRule annotationAdd BLAST21
Transmembranei404 – 424HelicalUniRule annotationAdd BLAST21
Transmembranei428 – 448HelicalUniRule annotationAdd BLAST21
Transmembranei464 – 484HelicalUniRule annotationAdd BLAST21
Transmembranei493 – 513HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001457151 – 549Cation/acetate symporter ActPAdd BLAST549

Structurei

3D structure databases

ProteinModelPortaliB1XCV3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107QN1 Bacteria
COG4147 LUCA
HOGENOMiHOG000242183
KOiK14393
OMAiIANLPGW

Family and domain databases

Gene3Di1.20.1730.10, 1 hit
HAMAPiMF_01426 Acet_symport_ActP, 1 hit
InterProiView protein in InterPro
IPR014083 Cation/Ac_symporter_ActP
IPR038377 Na/Glc_symporter_sf
IPR001734 Na/solute_symporter
IPR018212 Na/solute_symporter_CS
PfamiView protein in Pfam
PF00474 SSF, 1 hit
TIGRFAMsiTIGR00813 sss, 1 hit
TIGR02711 symport_actP, 1 hit
PROSITEiView protein in PROSITE
PS00456 NA_SOLUT_SYMP_1, 1 hit
PS00457 NA_SOLUT_SYMP_2, 1 hit
PS50283 NA_SOLUT_SYMP_3, 1 hit

Sequencei

Sequence statusi: Complete.

B1XCV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRVLTALAA TLPFAANAAD AISGAVERQP TNWQAIIMFL IFVVFTLGIT
60 70 80 90 100
YWASKRVRSR SDYYTAGGNI TGFQNGLAIA GDYMSAASFL GISALVFTSG
110 120 130 140 150
YDGLIYSLGF LVGWPIILFL IAERLRNLGR YTFADVASYR LKQGPIRILS
160 170 180 190 200
ACGSLVVVAL YLIAQMVGAG KLIELLFGLN YHIAVVLVGV LMMMYVLFGG
210 220 230 240 250
MLATTWVQII KAVLLLFGAS FMAFMVMKHV GFSFNNLFSE AMAVHPKGVD
260 270 280 290 300
IMKPGGLVKD PISALSLGLG LMFGTAGLPH ILMRFFTVSD AREARKSVFY
310 320 330 340 350
ATGFMGYFYI LTFIIGFGAI MLVGANPEYK DAAGHLIGGN NMAAVHLANA
360 370 380 390 400
VGGNLFLGFI SAVAFATILA VVAGLTLAGA SAVSHDLYAN VFKKGATERE
410 420 430 440 450
ELRVSKITVL ILGVIAIILG VLFENQNIAF MVGLAFAIAA SCNFPIILLS
460 470 480 490 500
MYWSKLTTRG AMMGGWLGLI TAVVLMILGP TIWVQILGHE KAIFPYEYPA
510 520 530 540
LFSITVAFLG IWFFSATDNS AEGARERELF RAQFIRSQTG FGVEQGRAH
Length:549
Mass (Da):59,197
Last modified:May 20, 2008 - v1
Checksum:iE7E116FB919D0FFD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000948 Genomic DNA Translation: ACB05064.1
RefSeqiWP_000832573.1, NC_010473.1

Genome annotation databases

EnsemblBacteriaiACB05064; ACB05064; ECDH10B_4257
KEGGiecd:ECDH10B_4257

Similar proteinsi

Entry informationi

Entry nameiACTP_ECODH
AccessioniPrimary (citable) accession number: B1XCV3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 20, 2008
Last modified: March 28, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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