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Protein

Alkanesulfonate monooxygenase

Gene

ssuD

Organism
Escherichia coli (strain K12 / DH10B)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the desulfonation of aliphatic sulfonates.UniRule annotation

Miscellaneous

FMNH2 which is absolutely required for this enzymatic reaction, is provided by SsuE.UniRule annotation

Catalytic activityi

An alkanesulfonate (R-CH2-SO3H) + FMNH2 + O2 = an aldehyde (R-CHO) + FMN + sulfite + H2O.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenase, Oxidoreductase
LigandFlavoprotein, FMN

Names & Taxonomyi

Protein namesi
Recommended name:
Alkanesulfonate monooxygenaseUniRule annotation (EC:1.14.14.5UniRule annotation)
Alternative name(s):
FMNH2-dependent aliphatic sulfonate monooxygenaseUniRule annotation
Gene namesi
Name:ssuDUniRule annotation
Ordered Locus Names:ECDH10B_1005
OrganismiEscherichia coli (strain K12 / DH10B)
Taxonomic identifieri316385 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001396201 – 381Alkanesulfonate monooxygenaseAdd BLAST381

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB1X8N9
SMRiB1X8N9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SsuD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D4R Bacteria
COG2141 LUCA
HOGENOMiHOG000134568
KOiK04091
OMAiNIFWFLP

Family and domain databases

Gene3Di3.20.20.30, 1 hit
HAMAPiMF_01229 Alkanesulf_monooxygen, 1 hit
InterProiView protein in InterPro
IPR019911 Alkanesulphonate_mOase_FMN-dep
IPR011251 Luciferase-like_dom
IPR036661 Luciferase-like_sf
PfamiView protein in Pfam
PF00296 Bac_luciferase, 1 hit
SUPFAMiSSF51679 SSF51679, 1 hit
TIGRFAMsiTIGR03565 alk_sulf_monoox, 1 hit

Sequencei

Sequence statusi: Complete.

B1X8N9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLNMFWFLP THGDGHYLGT EEGSRPVDHG YLQQIAQAAD RLGYTGVLIP
60 70 80 90 100
TGRSCEDAWL VAASMIPVTQ RLKFLVALRP SVTSPTVAAR QAATLDRLSN
110 120 130 140 150
GRALFNLVTG SDPQELAGDG VFLDHSERYE ASAEFTQVWR RLLQRETVDF
160 170 180 190 200
NGKHIHVRGA KLLFPAIQQP YPPLYFGGSS DVAQELAAEQ VDLYLTWGEP
210 220 230 240 250
PELVKEKIEQ VRAKAAAHGR KIRFGIRLHV IVRETNDEAW QAAERLISHL
260 270 280 290 300
DDETIAKAQA AFARTDSVGQ QRMAALHNGK RDNLEISPNL WAGVGLVRGG
310 320 330 340 350
AGTALVGDGP TVAARINEYA ALGIDSFVLS GYPHLEEAYR VGELLFPLLD
360 370 380
VAIPEIPQPQ PLNPQGEAVA NDFIPRKVAQ S
Length:381
Mass (Da):41,736
Last modified:May 20, 2008 - v1
Checksum:i4D05E510487999C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000948 Genomic DNA Translation: ACB02135.1
RefSeqiWP_000056006.1, NC_010473.1

Genome annotation databases

EnsemblBacteriaiACB02135; ACB02135; ECDH10B_1005
KEGGiecd:ECDH10B_1005

Similar proteinsi

Entry informationi

Entry nameiSSUD_ECODH
AccessioniPrimary (citable) accession number: B1X8N9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 20, 2008
Last modified: October 25, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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