Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Protein kinase C substrate 80K-H

Gene

Prkcsh

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi221 – 232PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase
LigandCalciumPROSITE-ProRule annotation

Enzyme and pathway databases

ReactomeiR-RNO-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-RNO-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle
R-RNO-8957275 Post-translational protein phosphorylation
R-RNO-901042 Calnexin/calreticulin cycle

Names & Taxonomyi

Protein namesi
Submitted name:
Protein kinase C substrate 80K-HImported
Submitted name:
Protein kinase C substrate 80K-H (Predicted), isoform CRA_bImported
Gene namesi
Name:PrkcshImported
Synonyms:Prkcsh_predictedImported
ORF Names:rCG_31596Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1309628 Prkcsh

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000013360 Expressed in 10 organ(s), highest expression level in adult mammalian kidney

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000018009

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini208 – 243EF-handInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili151 – 185Sequence analysisAdd BLAST35
Coiled coili307 – 327Sequence analysisAdd BLAST21
Coiled coili364 – 394Sequence analysisAdd BLAST31

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2397 Eukaryota
ENOG410XPE3 LUCA
GeneTreeiENSGT00510000047770
HOGENOMiHOG000007805
HOVERGENiHBG051738
KOiK08288
OMAiCYELTTN
OrthoDBiEOG091G06YU
TreeFamiTF329550

Family and domain databases

Gene3Di2.70.130.10, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR026874 Glucosidase_2_bsu
IPR009011 Man6P_isomerase_rcpt-bd_dom_sf
IPR036607 PRKCSH
IPR028146 PRKCSH_N
PANTHERiPTHR12630:SF1 PTHR12630:SF1, 1 hit
PfamiView protein in Pfam
PF13202 EF-hand_5, 1 hit
PF12999 PRKCSH-like, 1 hit
PF13015 PRKCSH_1, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 1 hit

Sequencei

Sequence statusi: Complete.

B1WC34-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLLLLLLPL CWAVEVKRPR GVSLSNHHFY DESKPFTCLD GTATIPFDQV
60 70 80 90 100
NDDYCDCKDG SDEPGTAACP NGSFHCTNTG YKPLYILSSR VNDGVCDCCD
110 120 130 140 150
GTDEYNSGTV CENTCREKGR KEKESLQQLA EVTREGFRLK KILIEEWKTA
160 170 180 190 200
REEKQSKLLE LQAGKKSLED QVETLRTAKE EAERPEKEAK DQHRKLWEEQ
210 220 230 240 250
QAAAKARREQ ELAASAFQEL DDNMDGLVSL AELQTHPELD TDGDGGLSEE
260 270 280 290 300
EAQALLSGDT QTDTTSFYDR VWAAIRDKYR SEVPPTDIPV PEVTEPKEEK
310 320 330 340 350
LPVLPPMEEE EEEEEPEEEE EEEEEEVPGE QPKEVPPPQQ PLRPPSPAED
360 370 380 390 400
EKMPPYDEET QAIIDAAQEA RNKFEEVERS LKEMEESIRS LEQEISFDFG
410 420 430 440 450
PSGEFAYLYS QCYELTTNEY VYRLCPFKLV SQKPKHGGSP TSLGTWGSWA
460 470 480 490 500
GPDDDKFSAM KYEQGTGCWQ GPNRSTTVRL LCGKETVVTS TTEPSRCEYL
510 520
MELMTPAACP EPPPEVPTDG DHDEL
Length:525
Mass (Da):59,218
Last modified:May 20, 2008 - v1
Checksum:iC9C1089E36012BE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07073372 Genomic DNA No translation available.
BC161987 mRNA Translation: AAI61987.1
CH473993 Genomic DNA Translation: EDL78243.1
RefSeqiNP_001100276.1, NM_001106806.2
XP_006242695.1, XM_006242633.3
UniGeneiRn.104417

Genome annotation databases

EnsembliENSRNOT00000018009; ENSRNOP00000018009; ENSRNOG00000013360
GeneIDi300445
KEGGirno:300445
UCSCiRGD:1309628 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07073372 Genomic DNA No translation available.
BC161987 mRNA Translation: AAI61987.1
CH473993 Genomic DNA Translation: EDL78243.1
RefSeqiNP_001100276.1, NM_001106806.2
XP_006242695.1, XM_006242633.3
UniGeneiRn.104417

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000018009

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000018009; ENSRNOP00000018009; ENSRNOG00000013360
GeneIDi300445
KEGGirno:300445
UCSCiRGD:1309628 rat

Organism-specific databases

CTDi5589
RGDi1309628 Prkcsh

Phylogenomic databases

eggNOGiKOG2397 Eukaryota
ENOG410XPE3 LUCA
GeneTreeiENSGT00510000047770
HOGENOMiHOG000007805
HOVERGENiHBG051738
KOiK08288
OMAiCYELTTN
OrthoDBiEOG091G06YU
TreeFamiTF329550

Enzyme and pathway databases

ReactomeiR-RNO-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-RNO-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle
R-RNO-8957275 Post-translational protein phosphorylation
R-RNO-901042 Calnexin/calreticulin cycle

Gene expression databases

BgeeiENSRNOG00000013360 Expressed in 10 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

Gene3Di2.70.130.10, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR026874 Glucosidase_2_bsu
IPR009011 Man6P_isomerase_rcpt-bd_dom_sf
IPR036607 PRKCSH
IPR028146 PRKCSH_N
PANTHERiPTHR12630:SF1 PTHR12630:SF1, 1 hit
PfamiView protein in Pfam
PF13202 EF-hand_5, 1 hit
PF12999 PRKCSH-like, 1 hit
PF13015 PRKCSH_1, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB1WC34_RAT
AccessioniPrimary (citable) accession number: B1WC34
Entry historyiIntegrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: October 10, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again