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UniProtKB - B1WC18 (B1WC18_RAT)
Protein
Submitted name:
Podocalyxin-like 2
Gene
Podxl2
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Biological processi
- leukocyte tethering or rolling Source: RGD
Enzyme and pathway databases
Reactomei | R-RNO-156584, Cytosolic sulfonation of small molecules |
Names & Taxonomyi
Protein namesi | Submitted name: Podocalyxin-like 2ImportedSubmitted name: Podocalyxin-like 2 (Predicted)Imported |
Gene namesi | ORF Names:rCG_56509Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1305815, Podxl2 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 497 – 521 | HelicalSequence analysisAdd BLAST | 25 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 28 | Sequence analysisAdd BLAST | 28 | |
ChainiPRO_5014298262 | 29 – 603 | Sequence analysisAdd BLAST | 575 |
Keywords - PTMi
GlycoproteinARBA annotationExpressioni
Gene expression databases
Bgeei | ENSRNOG00000016255, Expressed in cerebellum and 21 other tissues |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 54 – 89 | DisorderedSequence analysisAdd BLAST | 36 | |
Regioni | 124 – 368 | DisorderedSequence analysisAdd BLAST | 245 | |
Regioni | 558 – 603 | DisorderedSequence analysisAdd BLAST | 46 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 154 – 189 | Acidic residuesSequence analysisAdd BLAST | 36 | |
Compositional biasi | 193 – 220 | Polar residuesSequence analysisAdd BLAST | 28 | |
Compositional biasi | 229 – 269 | Polar residuesSequence analysisAdd BLAST | 41 | |
Compositional biasi | 300 – 314 | Polar residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 335 – 368 | Polar residuesSequence analysisAdd BLAST | 34 | |
Compositional biasi | 558 – 583 | Polar residuesSequence analysisAdd BLAST | 26 | |
Compositional biasi | 588 – 603 | Basic and acidic residuesSequence analysisAdd BLAST | 16 |
Keywords - Domaini
SignalSequence analysisARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | ENOG502QTNA, Eukaryota |
GeneTreei | ENSGT00730000111323 |
HOGENOMi | CLU_039299_0_0_1 |
OMAi | LLEFAMM |
OrthoDBi | 1103853at2759 |
TreeFami | TF333564 |
Family and domain databases
InterProi | View protein in InterPro IPR013836, CD34/Podocalyxin IPR042397, PODXL2 |
PANTHERi | PTHR15594, PTHR15594, 1 hit |
Pfami | View protein in Pfam PF06365, CD34_antigen, 1 hit |
i Sequence
Sequence statusi: Complete.
B1WC18-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MARPLRAAGL PPPLLLLLAA GVSLGACAVT MDEPGPEGLT STSLLDLLLP
60 70 80 90 100
TDFEPLDSEE PSEAMGLGAG LAPGSGFPSE DSEESRLLQP PQYFWEEEEL
110 120 130 140 150
NGSSLDLGPT ADYVFPDLTE KVASMEDPGQ APDLPNLPSI LPKMDLAEPP
160 170 180 190 200
WHMPLEEEEE EEEEEEEEER EEEEREKEEA EEEEEEELLP VSGSPGATTQ
210 220 230 240 250
AHAPSPSTSS TSSQSPGATR HRQDDSGDQA TSGIEVESSV KPTLSVPSVT
260 270 280 290 300
PSTVALGVQN YSQESGGTEW PTGGLGVQSE VPQGAGEEAT VGAADYDGQQ
310 320 330 340 350
GALPSTSLPQ TVPPSGTEVP GEGPLYPRTP DSFPPGPQDT ESTPSSATWG
360 370 380 390 400
QEGLSEQPLE GQTAEAHSLT PWDSTQVICK DWSNLAGKSY VILNMTENID
410 420 430 440 450
CEVFRRHRGL RLLALVEEVL PRHRSGHRGD WHISLSKPSE KEQHLLMTLV
460 470 480 490 500
GEQGVVPTQD VLSMLSGIRR SLEEIGIQNY STTSSCQARA TQVRSDYGTL
510 520 530 540 550
FVVLVIIGVI CFIIIVLGLL YNCWQRRLPK LKHVSHGEEL RFVENGCHDN
560 570 580 590 600
PTLDVASDSQ SEMQEKQPSL NGGAINGPSS WSALMGSKRD PEDSDVFEED
THL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC120997 Genomic DNA No translation available. BC161970 mRNA Translation: AAI61970.1 CH473957 Genomic DNA Translation: EDL91320.1 |
RefSeqi | NP_001100077.1, NM_001106607.1 |
Genome annotation databases
Ensembli | ENSRNOT00000021826; ENSRNOP00000021826; ENSRNOG00000016255 |
GeneIDi | 297433 |
KEGGi | rno:297433 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC120997 Genomic DNA No translation available. BC161970 mRNA Translation: AAI61970.1 CH473957 Genomic DNA Translation: EDL91320.1 |
RefSeqi | NP_001100077.1, NM_001106607.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000021826 |
Genome annotation databases
Ensembli | ENSRNOT00000021826; ENSRNOP00000021826; ENSRNOG00000016255 |
GeneIDi | 297433 |
KEGGi | rno:297433 |
Organism-specific databases
CTDi | 50512 |
RGDi | 1305815, Podxl2 |
Phylogenomic databases
eggNOGi | ENOG502QTNA, Eukaryota |
GeneTreei | ENSGT00730000111323 |
HOGENOMi | CLU_039299_0_0_1 |
OMAi | LLEFAMM |
OrthoDBi | 1103853at2759 |
TreeFami | TF333564 |
Enzyme and pathway databases
Reactomei | R-RNO-156584, Cytosolic sulfonation of small molecules |
Gene expression databases
Bgeei | ENSRNOG00000016255, Expressed in cerebellum and 21 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR013836, CD34/Podocalyxin IPR042397, PODXL2 |
PANTHERi | PTHR15594, PTHR15594, 1 hit |
Pfami | View protein in Pfam PF06365, CD34_antigen, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | B1WC18_RAT | |
Accessioni | B1WC18Primary (citable) accession number: B1WC18 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 20, 2008 |
Last sequence update: | May 20, 2008 | |
Last modified: | January 19, 2022 | |
This is version 95 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |