Zfp2

Functionⁱ

GO - Molecular functionⁱ

DNA-binding transcription factor activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
sequence-specific DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

negative regulation of transcription, DNA-templated
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
positive regulation of transcription, DNA-templated
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
positive regulation of transcription by RNA polymerase II
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Enzyme and pathway databases

Reactomeⁱ	R-RNO-212436 Generic Transcription Pathway

Reactomeⁱ

R-RNO-212436 Generic Transcription Pathway

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: RCG63490Imported Submitted name: Zfp2 proteinImported Submitted name: Zinc finger protein 2Imported
Gene namesⁱ	Name:Zfp2Imported ORF Names:rCG_63490Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 10

Organism-specific databases

Rat genome database More...RGDⁱ	1562610 Zfp2

RGDⁱ

1562610 Zfp2

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000030750 Expressed in 9 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000030750 Expressed in 9 organ(s), highest expression level in brain

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000041481

STRINGⁱ

10116.ENSRNOP00000041481

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	102 – 129	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	130 – 157	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	158 – 185	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	186 – 213	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	214 – 241	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	242 – 269	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	270 – 297	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	298 – 325	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	326 – 353	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	354 – 381	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	382 – 409	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	410 – 437	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	438 – 461	C2H2-typeInterPro annotationAdd BLAST	24

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00930000150844
HOGENOMⁱ	HOG000234617
HOVERGENⁱ	HBG018163
OMAⁱ	KKIYECN
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02KC
TreeFamⁱ	TF350858

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 13 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 13 hits
SUPFAMⁱ	SSF57667 SSF57667, 7 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 13 hits PS50157 ZINC_FINGER_C2H2_2, 13 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

B1WBX4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDREDLWHSA LGAVWDSTCW LEEQQERYLG QVTVTQKEIF NEKRVCGGNK 
        60         70         80         90        100
TENGSIEHSM LSIPQSIPVT IRLCNWNSYG KGSNQNPKLM KSSRMFVRKK 
       110        120        130        140        150
IYECDECGKS FSQSSSLLKH QRIHTGEKPY KCNVCDKHFI ERSSLTVHQR 
       160        170        180        190        200
THTGEKPYKC NECGKAFSQS MNLTVHQRTH TGEKPYQCKE CGKAFRKNSS 
       210        220        230        240        250
LIQHERIHTG EKPYKCNDCG KAFTQSMNLT VHQRTHTGEK PYECNQCGKA 
       260        270        280        290        300
FSQSMHLIVH QRSHTGEKPY ECSECGKAFS KSSTLTLHQR NHTGEKPYKC 
       310        320        330        340        350
NKCGKSFSQS TYLIEHQRLH SGVKPFECNQ CGKAFSKNSS LTQHRRIHTG 
       360        370        380        390        400
EKPYQCMVCG KHFTGRSSLT VHQVIHTGEK PYECTECGKA FSQSAYLIEH 
       410        420        430        440        450
QRIHTGEKPY ECDQCGKAFI KNSSLIVHQR IHTGEKPYKC NECGKSFSRS 
       460 
TNLTRHQRTH T

Length:461

Mass (Da):52,861

Last modified:May 20, 2008 - v1

Checksum:ⁱABEBD92BE2F5D2F1

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	461	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC115666 Genomic DNA No translation available. BC161925 mRNA Translation: AAI61925.1 CH473948 Genomic DNA Translation: EDM04289.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001121030.1, NM_001127558.1
UniGeneⁱ	Rn.216113

Genome annotation databases

Ensemblⁱ	ENSRNOT00000040346; ENSRNOP00000041481; ENSRNOG00000030750
GeneIDⁱ	497897
KEGGⁱ	rno:497897

Protein	Similar proteins		Species	Score	Length	Source
B1WBX4	Zinc finger protein 2		MOUSE		459	UniRef90_P08043
UPI000A31A647		MUSCR		459
UPI0007EC716E		MOUSE		494

Protein	Similar proteins		Species	Score	Length	Source
B1WBX4	Zinc finger protein 2		MOUSE		459	UniRef50_P08043
zinc finger protein 3 homolog isoform X1		ERIEU		501
Zinc finger protein 16		CRIGR		539
Uncharacterized protein		PELSI		497
zinc finger protein 420-like		ALLSI		505
+14

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC115666 Genomic DNA No translation available. BC161925 mRNA Translation: AAI61925.1 CH473948 Genomic DNA Translation: EDM04289.1
RefSeqⁱ	NP_001121030.1, NM_001127558.1
UniGeneⁱ	Rn.216113

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000041481

STRINGⁱ

10116.ENSRNOP00000041481

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000040346; ENSRNOP00000041481; ENSRNOG00000030750
GeneIDⁱ	497897
KEGGⁱ	rno:497897

Organism-specific databases

CTDⁱ	80108
RGDⁱ	1562610 Zfp2

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00930000150844
HOGENOMⁱ	HOG000234617
HOVERGENⁱ	HBG018163
OMAⁱ	KKIYECN
OrthoDBⁱ	EOG091G02KC
TreeFamⁱ	TF350858

Enzyme and pathway databases

Reactomeⁱ	R-RNO-212436 Generic Transcription Pathway

Reactomeⁱ

R-RNO-212436 Generic Transcription Pathway

Gene expression databases

Bgeeⁱ	ENSRNOG00000030750 Expressed in 9 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000030750 Expressed in 9 organ(s), highest expression level in brain

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 13 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 13 hits
SUPFAMⁱ	SSF57667 SSF57667, 7 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 13 hits PS50157 ZINC_FINGER_C2H2_2, 13 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	B1WBX4_RAT
Accessionⁱ	B1WBX4Primary (citable) accession number: B1WBX4
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 20, 2008
	Last sequence update:	May 20, 2008
	Last modified:	November 7, 2018
	This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - B1WBX4 (B1WBX4_RAT)

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RCG63490

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ