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Entry version 78 (02 Dec 2020)
Sequence version 1 (20 May 2008)
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Protein

Segment polarity protein dishevelled homolog DVL-3

Gene

dvl3

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the signal transduction pathway mediated by multiple Wnt genes (By similarity). Required during ciliogenesis for the docking of basal bodies to the apical plasma membrane (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processCilium biogenesis/degradation, Wnt signaling pathway

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-XTR-201688, WNT mediated activation of DVL
R-XTR-4086400, PCP/CE pathway
R-XTR-4641262, Disassembly of the destruction complex and recruitment of AXIN to the membrane
R-XTR-5663220, RHO GTPases Activate Formins

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Segment polarity protein dishevelled homolog DVL-3By similarity
Short name:
Dishevelled-3By similarity
Alternative name(s):
DSH homolog 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:dvl3By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8364 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008143 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...
Xenbasei
XB-GENE-977362, dvl3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003546671 – 713Segment polarity protein dishevelled homolog DVL-3Add BLAST713

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
B1WAP7

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
8364.ENSXETP00000037606

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
B1WAP7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 82DIXPROSITE-ProRule annotationAdd BLAST82
Domaini248 – 333PDZPROSITE-ProRule annotationAdd BLAST86
Domaini421 – 495DEPPROSITE-ProRule annotationAdd BLAST75

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi627 – 646His-richSequence analysisAdd BLAST20

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DSH family.Sequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3571, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012601_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
B1WAP7

Database of Orthologous Groups

More...
OrthoDBi
474724at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.10, 1 hit
2.30.42.10, 1 hit
3.10.20.380, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000591, DEP_dom
IPR024580, Dishevelled_C-dom
IPR008339, Dishevelled_fam
IPR003351, Dishevelled_protein_dom
IPR001158, DIX
IPR038207, DIX_dom_sf
IPR015506, Dsh/Dvl-rel
IPR008342, DVL3
IPR001478, PDZ
IPR036034, PDZ_sf
IPR029071, Ubiquitin-like_domsf
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10878, PTHR10878, 1 hit
PTHR10878:SF6, PTHR10878:SF6, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00610, DEP, 1 hit
PF02377, Dishevelled, 1 hit
PF00778, DIX, 1 hit
PF12316, Dsh_C, 1 hit
PF00595, PDZ, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01760, DISHEVELLED

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00021, DAX, 1 hit
SM00049, DEP, 1 hit
SM00228, PDZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46785, SSF46785, 1 hit
SSF50156, SSF50156, 1 hit
SSF54236, SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50186, DEP, 1 hit
PS50841, DIX, 1 hit
PS50106, PDZ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 16 potential isoforms that are computationally mapped.Show allAlign All

B1WAP7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGETKVIYHL DEQETPYLVK LPVPAEKVTL GDFKNVLNKP NYKFFFKSMD
60 70 80 90 100
DDFGVVKEEI SDDNAKLPCF NGRVVCWLVS ADGSQSDAGS VCADNQSDLP
110 120 130 140 150
PPIERTGGIG DSRPPSFHPN TRGSQENLDN ETETDSVVSA HRERPRRKET
160 170 180 190 200
PEHATRLNGT SKMERRRDTG GYESSSTLMS SELDSTSFFD SDEDDSTSRF
210 220 230 240 250
SNSTEQSSAS RLMRRHKRRR RKPKAPRIER SSSFSSITDS TMSLNIITVT
260 270 280 290 300
LNMEKYNFLG ISIVGQSNER GDGGIYIGSI MKGGAVAADG RIEPGDMLLQ
310 320 330 340 350
VNDTNFENMS NDDAVRVLRE IVHKPGPITL TVAKCWDPSP RNCFTLPRSE
360 370 380 390 400
PIRPIDPAAW VSHTAAMTGS YPAYGMSPSM STITSTSSSI TSSIPETERF
410 420 430 440 450
DDFQLSIHSD MVTIVKAMRS PESGLEVRDR MWLKITIPNA FIGSDVVDWL
460 470 480 490 500
YHHVEGFTDR REARKYASNL LKAGYIRHTV NKITFSEQCY YIFGDLCGNM
510 520 530 540 550
ANLSLNDHDG SSGTSDQDTL APLPHPGAAP WPIAFQYQYP LPHPYSPHPG
560 570 580 590 600
FPDPAYSYGG GSAGSQHSEG SRSSGSNRSS TEKRKEREAK GGDTKSGGSG
610 620 630 640 650
SESDHTTRSS VRRERAASER SVPASEHSHR SHHSIAHSIR SHHTHHSFGP
660 670 680 690 700
PGIPPLYGAP MMMMPAPASV IGPPGAPPSR DLASVPPELT ASRQSFRMAM
710
GNPTKNSGVF DFL
Length:713
Mass (Da):78,314
Last modified:May 20, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE43625C6BC9E79A4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 16 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F7CXU8F7CXU8_XENTR
Segment polarity protein dishevelle...
sema6a dvl3
983Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8QKN3A0A6I8QKN3_XENTR
Semaphorin 6A
sema6a
972Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8PYN2A0A6I8PYN2_XENTR
Semaphorin 6A
sema6a
1,036Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8QAJ4A0A6I8QAJ4_XENTR
Semaphorin 6A
sema6a
974Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8QBL4A0A6I8QBL4_XENTR
Semaphorin 6A
sema6a
1,025Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8R2E2A0A6I8R2E2_XENTR
Semaphorin 6A
sema6a
1,024Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8R3M9A0A6I8R3M9_XENTR
Semaphorin 6A
sema6a
985Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8RHK0A0A6I8RHK0_XENTR
Semaphorin 6A
sema6a
938Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6UUL1F6UUL1_XENTR
Semaphorin 6A
sema6a
899Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8SWQ7A0A6I8SWQ7_XENTR
Semaphorin 6A
sema6a
916Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC161453 mRNA Translation: AAI61453.1

NCBI Reference Sequences

More...
RefSeqi
NP_001116929.1, NM_001123457.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSXETT00000037606; ENSXETP00000037606; ENSXETG00000017275

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100144702

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
xtr:100144702

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC161453 mRNA Translation: AAI61453.1
RefSeqiNP_001116929.1, NM_001123457.1

3D structure databases

SMRiB1WAP7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000037606

Proteomic databases

PaxDbiB1WAP7

Genome annotation databases

EnsembliENSXETT00000037606; ENSXETP00000037606; ENSXETG00000017275
GeneIDi100144702
KEGGixtr:100144702

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1857
XenbaseiXB-GENE-977362, dvl3

Phylogenomic databases

eggNOGiKOG3571, Eukaryota
HOGENOMiCLU_012601_1_0_1
InParanoidiB1WAP7
OrthoDBi474724at2759

Enzyme and pathway databases

ReactomeiR-XTR-201688, WNT mediated activation of DVL
R-XTR-4086400, PCP/CE pathway
R-XTR-4641262, Disassembly of the destruction complex and recruitment of AXIN to the membrane
R-XTR-5663220, RHO GTPases Activate Formins

Family and domain databases

Gene3Di1.10.10.10, 1 hit
2.30.42.10, 1 hit
3.10.20.380, 1 hit
InterProiView protein in InterPro
IPR000591, DEP_dom
IPR024580, Dishevelled_C-dom
IPR008339, Dishevelled_fam
IPR003351, Dishevelled_protein_dom
IPR001158, DIX
IPR038207, DIX_dom_sf
IPR015506, Dsh/Dvl-rel
IPR008342, DVL3
IPR001478, PDZ
IPR036034, PDZ_sf
IPR029071, Ubiquitin-like_domsf
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf
PANTHERiPTHR10878, PTHR10878, 1 hit
PTHR10878:SF6, PTHR10878:SF6, 1 hit
PfamiView protein in Pfam
PF00610, DEP, 1 hit
PF02377, Dishevelled, 1 hit
PF00778, DIX, 1 hit
PF12316, Dsh_C, 1 hit
PF00595, PDZ, 1 hit
PRINTSiPR01760, DISHEVELLED
SMARTiView protein in SMART
SM00021, DAX, 1 hit
SM00049, DEP, 1 hit
SM00228, PDZ, 1 hit
SUPFAMiSSF46785, SSF46785, 1 hit
SSF50156, SSF50156, 1 hit
SSF54236, SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50186, DEP, 1 hit
PS50841, DIX, 1 hit
PS50106, PDZ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDVL3_XENTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B1WAP7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: May 20, 2008
Last modified: December 2, 2020
This is version 78 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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