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UniProtKB - B1W5S5 (Y6403_STRGG)
Protein
Putative (5-formylfuran-3-yl)methyl phosphate synthase
Gene
SGR_6403
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
Status
Functioni
Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
By similarityCatalytic activityi
- 2 D-glyceraldehyde 3-phosphate = 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + 2 H2O + phosphateBy similarityEC:4.2.3.153By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 29 | Schiff-base intermediate with substrateBy similarity | 1 | |
Active sitei | 87 | Proton acceptorBy similarity | 1 |
GO - Molecular functioni
- lyase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Lyase |
Ligand | Schiff base |
Names & Taxonomyi
Protein namesi | Recommended name: Putative (5-formylfuran-3-yl)methyl phosphate synthaseBy similarity (EC:4.2.3.153By similarity)Alternative name(s): 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthaseBy similarity Short name: 4-HFC-P synthaseBy similarity |
Gene namesi | Ordered Locus Names:SGR_6403 |
Organismi | Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) |
Taxonomic identifieri | 455632 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Streptomycetales › Streptomycetaceae › Streptomyces › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000131716 | 1 – 250 | Putative (5-formylfuran-3-yl)methyl phosphate synthaseAdd BLAST | 250 |
Family & Domainsi
Sequence similaritiesi
Belongs to the MfnB family.Curated
Phylogenomic databases
eggNOGi | COG1891, Bacteria |
HOGENOMi | CLU_068659_0_0_11 |
OMAi | NFPWVIR |
OrthoDBi | 1796491at2 |
Family and domain databases
InterProi | View protein in InterPro IPR007565, 4HFCP_synth IPR011060, RibuloseP-bd_barrel |
Pfami | View protein in Pfam PF04476, 4HFCP_synth, 1 hit |
PIRSFi | PIRSF015957, UCP015957, 1 hit |
SUPFAMi | SSF51366, SSF51366, 1 hit |
i Sequence
Sequence statusi: Complete.
B1W5S5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLLLISPDGV EEALACATAA EHLDIVDVKK PDEGSLGANF PWVIREIRAA
60 70 80 90 100
VPADKPVSAT VGDVPYKPGT VAQAALGAAV SGATYIKVGL YGCATPDQAI
110 120 130 140 150
DVMRGVVRAV KDFRADAFVV ASGYADAHRI GCVNPLALPD IARRAGADAA
160 170 180 190 200
MLDTAIKDGT RLFDHVPPEG CAEFVRLAHE AGLLAALAGS VKAADLATLT
210 220 230 240 250
RIGTDIVGVR GAVCEGGDRD AGRIQPRLVA AFRAEMDRHA RAFAAAPAAS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP009493 Genomic DNA Translation: BAG23232.1 |
RefSeqi | WP_012381917.1, NC_010572.1 |
Genome annotation databases
EnsemblBacteriai | BAG23232; BAG23232; SGR_6403 |
GeneIDi | 6209015 |
KEGGi | sgr:SGR_6403 |
PATRICi | fig|455632.4.peg.6564 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP009493 Genomic DNA Translation: BAG23232.1 |
RefSeqi | WP_012381917.1, NC_010572.1 |
3D structure databases
SMRi | B1W5S5 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 455632.SGR_6403 |
Genome annotation databases
EnsemblBacteriai | BAG23232; BAG23232; SGR_6403 |
GeneIDi | 6209015 |
KEGGi | sgr:SGR_6403 |
PATRICi | fig|455632.4.peg.6564 |
Phylogenomic databases
eggNOGi | COG1891, Bacteria |
HOGENOMi | CLU_068659_0_0_11 |
OMAi | NFPWVIR |
OrthoDBi | 1796491at2 |
Family and domain databases
InterProi | View protein in InterPro IPR007565, 4HFCP_synth IPR011060, RibuloseP-bd_barrel |
Pfami | View protein in Pfam PF04476, 4HFCP_synth, 1 hit |
PIRSFi | PIRSF015957, UCP015957, 1 hit |
SUPFAMi | SSF51366, SSF51366, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Y6403_STRGG | |
Accessioni | B1W5S5Primary (citable) accession number: B1W5S5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 14, 2009 |
Last sequence update: | May 20, 2008 | |
Last modified: | February 23, 2022 | |
This is version 61 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |