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Entry version 59 (26 Feb 2020)
Sequence version 1 (20 May 2008)
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Protein
Submitted name:

Putative ABC transporter permease protein

Gene

SGR_4406

Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
SGRI455632:G1G2X-4462-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative ABC transporter permease proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:SGR_4406Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStreptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri455632 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001685 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei270 – 296HelicalSequence analysisAdd BLAST27
Transmembranei319 – 343HelicalSequence analysisAdd BLAST25
Transmembranei363 – 385HelicalSequence analysisAdd BLAST23
Transmembranei412 – 431HelicalSequence analysisAdd BLAST20
Transmembranei443 – 476HelicalSequence analysisAdd BLAST34
Transmembranei497 – 517HelicalSequence analysisAdd BLAST21
Transmembranei733 – 758HelicalSequence analysisAdd BLAST26
Transmembranei783 – 803HelicalSequence analysisAdd BLAST21
Transmembranei823 – 846HelicalSequence analysisAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 39Sequence analysisAdd BLAST39
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500277002440 – 861Sequence analysisAdd BLAST822

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
455632.SGR_4406

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini19 – 236MacB_PCDInterPro annotationAdd BLAST218
Domaini300 – 395FtsXInterPro annotationAdd BLAST96
Domaini499 – 699MacB_PCDInterPro annotationAdd BLAST201
Domaini762 – 852FtsXInterPro annotationAdd BLAST91

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni57 – 79DisorderedSequence analysisAdd BLAST23

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4107RKB Bacteria
COG0577 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012341_1_0_11

KEGG Orthology (KO)

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KOi
K02004

Identification of Orthologs from Complete Genome Data

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OMAi
PQSFHWT

Database of Orthologous Groups

More...
OrthoDBi
856767at2

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR003838 ABC_permease_dom
IPR025857 MacB_PCD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02687 FtsX, 2 hits
PF12704 MacB_PCD, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B1VUK9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTVWKTSVRN FLAHKGRMAL SAVAVLLSVA FVSGTLVFTD TMNTTFDKLF
60 70 80 90 100
AVTSPDVTVS PKTSGGDDEQ PDNGKPASLP ASAVQEVAKA DGVKKAEGAV
110 120 130 140 150
FSMAVTVVNS ENKNMGSETG APTIAGNWTE NDLRSMEITA GHAPRGPTEV
160 170 180 190 200
MIDADTAKKH ELKLGDELRT IAATGDITAK ISGIASFTVT NPGAAVVYLD
210 220 230 240 250
TATAQKQLLG APDVFTQILV SAENGVSDTQ LKKNVATVLD GSAAYKLQTQ
260 270 280 290 300
QEATDANKDS MGSFLDVMKY AMLGFAGIAF LVGIFLIVNT FSMLVAQRTR
310 320 330 340 350
EIGLMRAIGS SRKQVNRSVL VEAVLLGIVG SVLGVAAGVG LAVGLMKAMG
360 370 380 390 400
AVGMELSTGD LTVAWTTPAI GLVLGVVVTV LAAYIPARRA GKVSPMAALR
410 420 430 440 450
DAGTPADGRS GWIRAGIGLL LTAAGGAALW ATTQADKATE GSTFLALGVL
460 470 480 490 500
LTLIGFIVIG PLLAGVVVRA LSVVVLRLFG PVGRLAERNA LRNPRRTGAT
510 520 530 540 550
GVALMIGLAL VACLSVVGSS MVASATEELD KSVGADFIVQ DSGTGRPIVP
560 570 580 590 600
QAAEALKDVP GLEHLTDYTF VKAKITSPDG KTEDDGITAA DPTYQQDVRR
610 620 630 640 650
SALSGDLAKA YGKDAMSVGE DYAEKHGVEV GDTLTVAFAA GKTAKLKVAA
660 670 680 690 700
ITSDDTNIDR GAMYTNLTTA ATYVPADRMP QNVAMFGKAE EGKEKEAYAA
710 720 730 740 750
LKSAMAEYPV YKVQNQADFK EDLKDQIGQL LNIVYGLLAL AIIVAVLGVV
760 770 780 790 800
NTLALSVVER TREIGLMRAI GLSRRQLRRM IRLESVVIAL FGALLGLGLG
810 820 830 840 850
MGWGTAAQKL LALEGLEVLE IPWPTILTVF ACSALVGLFA ALVPAFRAGR
860
MNVLNAIATD G
Length:861
Mass (Da):89,688
Last modified:May 20, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i11FE1894FCA7FD4C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AP009493 Genomic DNA Translation: BAG21235.1

NCBI Reference Sequences

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RefSeqi
WP_012380581.1, NC_010572.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
BAG21235; BAG21235; SGR_4406

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6209274

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sgr:SGR_4406

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|455632.4.peg.4494

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009493 Genomic DNA Translation: BAG21235.1
RefSeqiWP_012380581.1, NC_010572.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi455632.SGR_4406

Genome annotation databases

EnsemblBacteriaiBAG21235; BAG21235; SGR_4406
GeneIDi6209274
KEGGisgr:SGR_4406
PATRICifig|455632.4.peg.4494

Phylogenomic databases

eggNOGiENOG4107RKB Bacteria
COG0577 LUCA
HOGENOMiCLU_012341_1_0_11
KOiK02004
OMAiPQSFHWT
OrthoDBi856767at2

Enzyme and pathway databases

BioCyciSGRI455632:G1G2X-4462-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR003838 ABC_permease_dom
IPR025857 MacB_PCD
PfamiView protein in Pfam
PF02687 FtsX, 2 hits
PF12704 MacB_PCD, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB1VUK9_STRGG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B1VUK9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: February 26, 2020
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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