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Protein

Uracil-DNA glycosylase

Gene

ung

Organism
Leuconostoc citreum (strain KM20)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.UniRule annotation

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei64Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processDNA damage, DNA repair

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylaseUniRule annotation (EC:3.2.2.27UniRule annotation)
Short name:
UDGUniRule annotation
Gene namesi
Name:ungUniRule annotation
Ordered Locus Names:LCK_00553
OrganismiLeuconostoc citreum (strain KM20)
Taxonomic identifieri349519 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
Proteomesi
  • UP000002166 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000965911 – 219Uracil-DNA glycosylaseAdd BLAST219

Interactioni

Protein-protein interaction databases

STRINGi349519.LCK_00553

Structurei

3D structure databases

ProteinModelPortaliB1MXY4
SMRiB1MXY4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D5S Bacteria
COG0692 LUCA
HOGENOMiHOG000229528
KOiK03648
OMAiQANGLCF

Family and domain databases

CDDicd10027 UDG_F1, 1 hit
Gene3Di3.40.470.10, 1 hit
HAMAPiMF_00148 UDG, 1 hit
InterProiView protein in InterPro
IPR002043 UDG_fam1
IPR018085 Ura-DNA_Glyclase_AS
IPR005122 Uracil-DNA_glycosylase-like
IPR036895 Uracil-DNA_glycosylase-like_sf
PANTHERiPTHR11264 PTHR11264, 1 hit
PfamiView protein in Pfam
PF03167 UDG, 1 hit
SMARTiView protein in SMART
SM00986 UDG, 1 hit
SUPFAMiSSF52141 SSF52141, 1 hit
TIGRFAMsiTIGR00628 ung, 1 hit
PROSITEiView protein in PROSITE
PS00130 U_DNA_GLYCOSYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

B1MXY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLSHTTWAP YINAKLTPEQ INNIKQFLDV QYQEQSIFPP KEKVFAALSM
60 70 80 90 100
TSLDHTKVVI MGQDPYHGLG QAQGLSFSVP DAVPAPPSLQ NILKELATDI
110 120 130 140 150
GPRASHDLTS WAKQGVLLLN AVLTVPEGQA NAHAGLVWEP LTDAIIQAVS
160 170 180 190 200
DAGEPTVFIL WGKFAQSKRR YIDESKHLVL TAAHPSPLSA YRGFFGSHPF
210
SKANQFLTQN GRDSIHWLE
Length:219
Mass (Da):24,102
Last modified:April 29, 2008 - v1
Checksum:i2B03D53A2873999F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ489736 Genomic DNA Translation: ACA82386.1
RefSeqiWP_004900401.1, NC_010471.1

Genome annotation databases

EnsemblBacteriaiACA82386; ACA82386; LCK_00553
GeneIDi35825889
KEGGilci:LCK_00553

Similar proteinsi

Entry informationi

Entry nameiUNG_LEUCK
AccessioniPrimary (citable) accession number: B1MXY4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: April 25, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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