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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:MAB_1433
OrganismiMycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)
Taxonomic identifieri561007 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteroides abscessus
Proteomesi
  • UP000007137 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953821 – 550Arginine--tRNA ligaseAdd BLAST550

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi561007.MAB_1433

Structurei

3D structure databases

ProteinModelPortaliB1MLU2
SMRiB1MLU2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi130 – 140"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B1MLU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPADLADLL RSTATTVLDE RGLDTSALPA VVTVERPRNP EHGDYATNVA
60 70 80 90 100
LQVAKKVGVA PRDLAGWLVE ALVSHAAIAG AEIAGPGFVN LRIAADAQGT
110 120 130 140 150
IVANILKAGE TYGNSDAQGT HTINLEFVSA NPTGPIHIGG TRWAAVGDAL
160 170 180 190 200
GRLLARQGAK VTREYYFNDH GAQIDRFVRS LIASAEGKEA PEDGYAGDYI
210 220 230 240 250
ADIAKQVITQ RPEALTLTEP ERSEVFREIG VDLMFTHIKE SLHEFGTDFD
260 270 280 290 300
VFTHEDSMHT SGRVQEAIAQ LRKTGNIYEK DGASWLRSSN FGDDKDRVVI
310 320 330 340 350
KSDGNPAYIA GDIAYYLDKR ERGFDLCIYM LGADHHGYIA RLKAVAAALG
360 370 380 390 400
YDADSVEVLI GQMVNLVRDG QPVRMSKRAG TVITLDDLVD AIGVDAARYA
410 420 430 440 450
LIRSSVDTSI DIDLELWASA SSENPVYYVQ YAHARLCALA RNAADLGLQH
460 470 480 490 500
STEHLELLTH EKEGALIRGL GEFGRILQNA AALREPHRVA RYLEDIAGDY
510 520 530 540 550
HRFYDSCRVL PQGDETPGDL HAARLALCLA TRQVIANGLD ILGVSAPERM
Length:550
Mass (Da):59,679
Last modified:April 29, 2008 - v1
Checksum:iCB0FE1DE15A92015
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU458896 Genomic DNA Translation: CAM61519.1

Genome annotation databases

EnsemblBacteriaiCAM61519; CAM61519; MAB_1433

Similar proteinsi

Entry informationi

Entry nameiSYR_MYCA9
AccessioniPrimary (citable) accession number: B1MLU2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: June 20, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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