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Protein

50S ribosomal protein L6

Gene

rplF

Organism
Escherichia coli (strain SMS-3-5 / SECEC)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L6UniRule annotation
Gene namesi
Name:rplFUniRule annotation
Ordered Locus Names:EcSMS35_3600
OrganismiEscherichia coli (strain SMS-3-5 / SECEC)
Taxonomic identifieri439855 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000007011 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001439881 – 17750S ribosomal protein L6Add BLAST177

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei44N6-acetyllysineUniRule annotation1

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiB1LHB9

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB1LHB9
SMRiB1LHB9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL6 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000039903
KOiK02933
OMAiINNMVVG

Family and domain databases

Gene3Di3.90.930.12, 2 hits
HAMAPiMF_01365_B Ribosomal_L6_B, 1 hit
InterProiView protein in InterPro
IPR000702 Ribosomal_L6
IPR020040 Ribosomal_L6_a/b-dom
IPR036789 Ribosomal_L6_a/b-dom_sf
IPR019906 Ribosomal_L6_bac-type
IPR002358 Ribosomal_L6_CS
PANTHERiPTHR11655 PTHR11655, 1 hit
PTHR11655:SF14 PTHR11655:SF14, 1 hit
PfamiView protein in Pfam
PF00347 Ribosomal_L6, 2 hits
PIRSFiPIRSF002162 Ribosomal_L6, 1 hit
PRINTSiPR00059 RIBOSOMALL6
SUPFAMiSSF56053 SSF56053, 2 hits
TIGRFAMsiTIGR03654 L6_bact, 1 hit
PROSITEiView protein in PROSITE
PS00525 RIBOSOMAL_L6_1, 1 hit

Sequencei

Sequence statusi: Complete.

B1LHB9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRVAKAPVV VPAGVDVKIN GQVITIKGKN GELTRTLNDA VEVKHADNTL
60 70 80 90 100
TFGPRDGYAD GWAQAGTARA LLNSMVIGVT EGFTKKLQLV GVGYRAAVKG
110 120 130 140 150
NVINLSLGFS HPVDHQLPAG ITAECPTQTE IVLKGADKQV IGQVAADLRA
160 170
YRRPEPYKGK GVRYADEVVR TKEAKKK
Length:177
Mass (Da):18,904
Last modified:April 29, 2008 - v1
Checksum:i946B64E9FA42FE61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000970 Genomic DNA Translation: ACB16428.1
RefSeqiWP_000091945.1, NC_010498.1

Genome annotation databases

EnsemblBacteriaiACB16428; ACB16428; EcSMS35_3600
KEGGiecm:EcSMS35_3600

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000970 Genomic DNA Translation: ACB16428.1
RefSeqiWP_000091945.1, NC_010498.1

3D structure databases

ProteinModelPortaliB1LHB9
SMRiB1LHB9
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB1LHB9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB16428; ACB16428; EcSMS35_3600
KEGGiecm:EcSMS35_3600

Phylogenomic databases

HOGENOMiHOG000039903
KOiK02933
OMAiINNMVVG

Family and domain databases

Gene3Di3.90.930.12, 2 hits
HAMAPiMF_01365_B Ribosomal_L6_B, 1 hit
InterProiView protein in InterPro
IPR000702 Ribosomal_L6
IPR020040 Ribosomal_L6_a/b-dom
IPR036789 Ribosomal_L6_a/b-dom_sf
IPR019906 Ribosomal_L6_bac-type
IPR002358 Ribosomal_L6_CS
PANTHERiPTHR11655 PTHR11655, 1 hit
PTHR11655:SF14 PTHR11655:SF14, 1 hit
PfamiView protein in Pfam
PF00347 Ribosomal_L6, 2 hits
PIRSFiPIRSF002162 Ribosomal_L6, 1 hit
PRINTSiPR00059 RIBOSOMALL6
SUPFAMiSSF56053 SSF56053, 2 hits
TIGRFAMsiTIGR03654 L6_bact, 1 hit
PROSITEiView protein in PROSITE
PS00525 RIBOSOMAL_L6_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRL6_ECOSM
AccessioniPrimary (citable) accession number: B1LHB9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: October 10, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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