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Protein

Translation initiation factor 5A

Gene

eIF5A

Organism
Korarchaeum cryptofilum (strain OPF8)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions by promoting the formation of the first peptide bond.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciCKOR374847:G1GBF-1677-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor 5AUniRule annotation
Alternative name(s):
Hypusine-containing proteinUniRule annotation
eIF-5AUniRule annotation
Gene namesi
Name:eIF5A
Ordered Locus Names:Kcr_1589
OrganismiKorarchaeum cryptofilum (strain OPF8)
Taxonomic identifieri374847 [NCBI]
Taxonomic lineageiArchaeaCandidatus KorarchaeotaCandidatus Korarchaeum
Proteomesi
  • UP000001686 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000930081 – 134Translation initiation factor 5AAdd BLAST134

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei36HypusineUniRule annotation1

Keywords - PTMi

Hypusine

Interactioni

Protein-protein interaction databases

STRINGi374847.Kcr_1589

Structurei

3D structure databases

ProteinModelPortaliB1L7A5
SMRiB1L7A5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-5A family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04277 Archaea
COG0231 LUCA
HOGENOMiHOG000106269
InParanoidiB1L7A5
KOiK03263
OMAiQIMDMET
OrthoDBiPOG093Z0HA5

Family and domain databases

Gene3Di2.30.30.30, 1 hit
HAMAPiMF_00085 eIF_5A, 1 hit
InterProiView protein in InterPro
IPR001884 IF5A-like
IPR012340 NA-bd_OB-fold
IPR014722 Rib_L2_dom2
IPR019769 Trans_elong_IF5A_hypusine_site
IPR022847 Transl_elong_IF5A_arc
IPR020189 Transl_elong_IF5A_C
IPR013185 Transl_elong_KOW-like
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR11673 PTHR11673, 1 hit
PfamiView protein in Pfam
PF08207 EFP_N, 1 hit
PF01287 eIF-5a, 1 hit
PIRSFiPIRSF003025 eIF5A, 1 hit
SMARTiView protein in SMART
SM01376 eIF-5a, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00037 eIF_5A, 1 hit
PROSITEiView protein in PROSITE
PS00302 IF5A_HYPUSINE, 1 hit

Sequencei

Sequence statusi: Complete.

B1L7A5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVTRGSAGD LRKGSYVILD DEPCEVLEVS KSKPGKHGSA KVRVEARGIF
60 70 80 90 100
DGARRSKIFP ADALVEIPIV DKKTAQVINV YGNVVQLMDL ETYETFELPL
110 120 130
PEDPELASRL KSGIEVEYWE SMGKRKIVRT RGGV
Length:134
Mass (Da):14,821
Last modified:April 29, 2008 - v1
Checksum:i8B3147BFBD2B2AAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000968 Genomic DNA Translation: ACB08334.1
RefSeqiWP_012310231.1, NC_010482.1

Genome annotation databases

EnsemblBacteriaiACB08334; ACB08334; Kcr_1589
GeneIDi6094865
KEGGikcr:Kcr_1589

Similar proteinsi

Entry informationi

Entry nameiIF5A_KORCO
AccessioniPrimary (citable) accession number: B1L7A5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: February 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

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