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UniProtKB - B1JSD2 (MDTD_YERPY)
Protein
Putative multidrug resistance protein MdtD
Gene
mdtD
Organism
Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Status
Functioni
GO - Molecular functioni
- transmembrane transporter activity Source: UniProtKB-UniRule
Keywordsi
Biological process | Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Putative multidrug resistance protein MdtDUniRule annotation |
Gene namesi | Name:mdtDUniRule annotation Ordered Locus Names:YPK_1329 |
Organismi | Yersinia pseudotuberculosis serotype O:3 (strain YPIII) |
Taxonomic identifieri | 502800 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Yersiniaceae › Yersinia › |
Subcellular locationi
Plasma membrane
- Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Plasma Membrane
- integral component of plasma membrane Source: UniProtKB-UniRule
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 12 – 32 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 49 – 69 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 72 – 92 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 102 – 124 | HelicalUniRule annotationAdd BLAST | 23 | |
Transmembranei | 138 – 158 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 165 – 185 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 195 – 215 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 219 – 239 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 267 – 287 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 290 – 310 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 342 – 362 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 393 – 413 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 430 – 450 | HelicalUniRule annotationAdd BLAST | 21 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000365295 | 1 – 465 | Putative multidrug resistance protein MdtDAdd BLAST | 465 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
OMAi | FKIHTFS |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
HAMAPi | MF_01577, MFS_MdtD, 1 hit |
InterProi | View protein in InterPro IPR004638, EmrB-like IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf IPR023721, Multi-R_MdtD |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00711, efflux_EmrB, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
B1JSD2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVTQATSVRW QLWIVAFGFF MQTLDTTIVN TALPSIAASL GENPLRMQSV
60 70 80 90 100
IVSYVLTVAV MLPASGWLAD RIGVKWVFFS AIILFTFGSL MCAQSATLNE
110 120 130 140 150
LILSRVLQGV GGAMMVPVGR LTVMKIVPRE QYMAAMAFVT LPGQIGPLVG
160 170 180 190 200
PALGGFLVEF ASWHWIFLIN LPVGVIGALA TLLLMPNHKM STRRFDISGF
210 220 230 240 250
IMLAIGMATL TLALDGHTGL GLSPLAIAGL ILCGVIALGS YWWHALGNRF
260 270 280 290 300
ALFSLHLFKN KIYTLGLVGS MSARIGSGML PFMTPIFLQI GLGFSPFHAG
310 320 330 340 350
LMMIPMIIGS MGMKRIIVQV VNRFGYRRVL VNATLLLAVV SLSLPLVAIM
360 370 380 390 400
GWTLLMPVVL FFQGMLNALR FSTMNTLTLK TLPDRLASSG NSLLSMAMQL
410 420 430 440 450
SMSIGVSTAG ILLGTFAHHQ VATNTPATHS AFLYSYLCMA IIIALPALIF
460
NRVPPDTGAN RHLAR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000950 Genomic DNA Translation: ACA67623.1 |
RefSeqi | WP_002209795.1, NZ_CP009792.1 |
Genome annotation databases
EnsemblBacteriai | ACA67623; ACA67623; YPK_1329 |
GeneIDi | 57975808 |
KEGGi | ypy:YPK_1329 |
PATRICi | fig|502800.11.peg.1964 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000950 Genomic DNA Translation: ACA67623.1 |
RefSeqi | WP_002209795.1, NZ_CP009792.1 |
3D structure databases
AlphaFoldDBi | B1JSD2 |
SMRi | B1JSD2 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | ACA67623; ACA67623; YPK_1329 |
GeneIDi | 57975808 |
KEGGi | ypy:YPK_1329 |
PATRICi | fig|502800.11.peg.1964 |
Phylogenomic databases
OMAi | FKIHTFS |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
HAMAPi | MF_01577, MFS_MdtD, 1 hit |
InterProi | View protein in InterPro IPR004638, EmrB-like IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf IPR023721, Multi-R_MdtD |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00711, efflux_EmrB, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MDTD_YERPY | |
Accessioni | B1JSD2Primary (citable) accession number: B1JSD2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 3, 2009 |
Last sequence update: | April 29, 2008 | |
Last modified: | May 25, 2022 | |
This is version 70 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |