TBC1 domain family, member 17

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• GTPase activator activity Source: GO_Central
• Rab GTPase binding Source: GO_Central

GO - Biological processⁱ

• activation of GTPase activity Source: GO_Central
• intracellular protein transport Source: GO_Central
• regulation of vesicle fusion Source: GO_Central
• retrograde transport, endosome to Golgi Source: Ensembl

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

GO - Molecular functionⁱ

• Rab GTPase binding Source: GO_Central

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MEGSSYRVVF EKGGVYLHTS ARKHQDPDSL IAGVLRVVEK DNDVLLHWAP 
        60         70         80         90        100
VEEAGDPTQI FFSKKDPSGG EPSTSEEEPT FDPGYEPDWA VISTVRPRPH 
       110        120        130        140        150
LAEPRRGAEP SSPRSSWAFS VSLGELKSIR RSKPGLSWAY LVLVTQAGGS 
       160        170        180        190        200
LPALHFHRGG TRALLRVLSR YLLLASSPQD SRLYLVFPQD PSALSDSFHH 
       210        220        230        240        250
LQLFDQDSSN VVSRFLQDPY STTFSSFSRV TNFFRGALQP HPEGASSPDL 
       260        270        280        290        300
PPLPDDEPEP GFEVISCVEL GQRPTVERAP PVTEEEWNRH VGPEGRLQNV 
       310        320        330        340        350
PELKSRIFSG GLSPGLRREA WKFLLGYLSW ESSAEEHKAH VRKKTDEYFR 
       360        370        380        390        400
MKLQWKSVSA EQERRNSLLH GYRSLIERDV SRTDRTNKFY EGPENPGLGL 
       410        420        430        440        450
LNDILLTYCM YHFDLGYVQG MSDLLSPILF VVQNEVDAFW CFCGFMELVH 
       460        470        480        490        500
GNFEESQETM KRQLGQLLLL LRVLDQPLCD FLDSQDSGSL CFCFRWLLIW 
       510        520        530        540        550
FKREFPFPDV LRLWEVLWTG LPGPNLHLLV ACAILDMERD TLMLSGFGSN 
       560        570        580        590        600
EILKHINELT MKLSVEDVLT RAEALYRQLT ACPELPHNVQ EILGLAQPEE 
       610        620        630        640 
PSSPSPPVSP MPLSPTRAPM PPPPPEEVAP QPDSSLEILP EDEDGA     

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ