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UniProtKB - B1H264 (B1H264_RAT)
Protein
Submitted name:
TBC1 domain family, member 17
Gene
Tbc1d17
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- GTPase activator activity Source: GO_Central
GO - Biological processi
- activation of GTPase activity Source: GO_Central
- intracellular protein transport Source: GO_Central
- retrograde transport, endosome to Golgi Source: RGD
Enzyme and pathway databases
Reactomei | R-RNO-8854214, TBC/RABGAPs |
Names & Taxonomyi
Protein namesi | Submitted name: TBC1 domain family, member 17ImportedSubmitted name: TBC1 domain family, member 17 (Predicted)Imported |
Gene namesi | ORF Names:rCG_54149Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1309686, Tbc1d17 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000020191, Expressed in pancreas and 20 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 311 – 521 | Rab-GAP TBCInterPro annotationAdd BLAST | 211 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 58 – 84 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 238 – 258 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 596 – 646 | DisorderedSequence analysisAdd BLAST | 51 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 600 – 630 | Pro residuesSequence analysisAdd BLAST | 31 |
Phylogenomic databases
eggNOGi | KOG2197, Eukaryota |
GeneTreei | ENSGT00940000158989 |
HOGENOMi | CLU_004457_2_2_1 |
OMAi | FAILMER |
OrthoDBi | 1495285at2759 |
TreeFami | TF314296 |
Family and domain databases
InterProi | View protein in InterPro IPR000195, Rab-GTPase-TBC_dom IPR035969, Rab-GTPase_TBC_sf IPR021935, SGSM1/2_RBD |
Pfami | View protein in Pfam PF12068, PH_RBD, 1 hit PF00566, RabGAP-TBC, 1 hit |
SMARTi | View protein in SMART SM00164, TBC, 1 hit |
SUPFAMi | SSF47923, SSF47923, 2 hits |
PROSITEi | View protein in PROSITE PS50086, TBC_RABGAP, 1 hit |
i Sequence
Sequence statusi: Complete.
B1H264-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEGSSYRVVF EKGGVYLHTS ARKHQDPDSL IAGVLRVVEK DNDVLLHWAP
60 70 80 90 100
VEEAGDPTQI FFSKKDPSGG EPSTSEEEPT FDPGYEPDWA VISTVRPRPH
110 120 130 140 150
LAEPRRGAEP SSPRSSWAFS VSLGELKSIR RSKPGLSWAY LVLVTQAGGS
160 170 180 190 200
LPALHFHRGG TRALLRVLSR YLLLASSPQD SRLYLVFPQD PSALSDSFHH
210 220 230 240 250
LQLFDQDSSN VVSRFLQDPY STTFSSFSRV TNFFRGALQP HPEGASSPDL
260 270 280 290 300
PPLPDDEPEP GFEVISCVEL GQRPTVERAP PVTEEEWNRH VGPEGRLQNV
310 320 330 340 350
PELKSRIFSG GLSPGLRREA WKFLLGYLSW ESSAEEHKAH VRKKTDEYFR
360 370 380 390 400
MKLQWKSVSA EQERRNSLLH GYRSLIERDV SRTDRTNKFY EGPENPGLGL
410 420 430 440 450
LNDILLTYCM YHFDLGYVQG MSDLLSPILF VVQNEVDAFW CFCGFMELVH
460 470 480 490 500
GNFEESQETM KRQLGQLLLL LRVLDQPLCD FLDSQDSGSL CFCFRWLLIW
510 520 530 540 550
FKREFPFPDV LRLWEVLWTG LPGPNLHLLV ACAILDMERD TLMLSGFGSN
560 570 580 590 600
EILKHINELT MKLSVEDVLT RAEALYRQLT ACPELPHNVQ EILGLAQPEE
610 620 630 640
PSSPSPPVSP MPLSPTRAPM PPPPPEEVAP QPDSSLEILP EDEDGA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC094894 Genomic DNA No translation available. BC160880 mRNA Translation: AAI60880.1 CH473979 Genomic DNA Translation: EDM07455.1 |
RefSeqi | NP_001099728.1, NM_001106258.2 |
Genome annotation databases
Ensembli | ENSRNOT00000027436; ENSRNOP00000027436; ENSRNOG00000020191 |
GeneIDi | 292886 |
KEGGi | rno:292886 |
UCSCi | RGD:1309686, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC094894 Genomic DNA No translation available. BC160880 mRNA Translation: AAI60880.1 CH473979 Genomic DNA Translation: EDM07455.1 |
RefSeqi | NP_001099728.1, NM_001106258.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000027436 |
Genome annotation databases
Ensembli | ENSRNOT00000027436; ENSRNOP00000027436; ENSRNOG00000020191 |
GeneIDi | 292886 |
KEGGi | rno:292886 |
UCSCi | RGD:1309686, rat |
Organism-specific databases
CTDi | 79735 |
RGDi | 1309686, Tbc1d17 |
Phylogenomic databases
eggNOGi | KOG2197, Eukaryota |
GeneTreei | ENSGT00940000158989 |
HOGENOMi | CLU_004457_2_2_1 |
OMAi | FAILMER |
OrthoDBi | 1495285at2759 |
TreeFami | TF314296 |
Enzyme and pathway databases
Reactomei | R-RNO-8854214, TBC/RABGAPs |
Gene expression databases
Bgeei | ENSRNOG00000020191, Expressed in pancreas and 20 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR000195, Rab-GTPase-TBC_dom IPR035969, Rab-GTPase_TBC_sf IPR021935, SGSM1/2_RBD |
Pfami | View protein in Pfam PF12068, PH_RBD, 1 hit PF00566, RabGAP-TBC, 1 hit |
SMARTi | View protein in SMART SM00164, TBC, 1 hit |
SUPFAMi | SSF47923, SSF47923, 2 hits |
PROSITEi | View protein in PROSITE PS50086, TBC_RABGAP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | B1H264_RAT | |
Accessioni | B1H264Primary (citable) accession number: B1H264 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 29, 2008 |
Last sequence update: | April 29, 2008 | |
Last modified: | January 19, 2022 | |
This is version 97 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |