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UniProtKB - B1H215 (B1H215_RAT)
Protein
Submitted name:
Nuclear receptor coactivator 4
Gene
Ncoa4
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- transcription coactivator activity Source: InterPro
GO - Biological processi
- cellular iron ion homeostasis Source: RGD
- protein targeting to lysosome Source: RGD
- response to hormone Source: RGD
Keywordsi
Molecular function | ReceptorImported |
Names & Taxonomyi
Protein namesi | Submitted name: Nuclear receptor coactivator 4ImportedSubmitted name: RCG42267, isoform CRA_aImported |
Gene namesi | Name:Ncoa4Imported ORF Names:rCG_42267Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1563014, Ncoa4 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000019768, Expressed in duodenum and 20 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 38 – 145 | ARA70InterPro annotationAdd BLAST | 108 | |
Domaini | 199 – 327 | ARA70InterPro annotationAdd BLAST | 129 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 265 – 287 | DisorderedSequence analysisAdd BLAST | 23 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 265 – 284 | Polar residuesSequence analysisAdd BLAST | 20 |
Phylogenomic databases
eggNOGi | ENOG502QQ6V, Eukaryota |
GeneTreei | ENSGT00390000008403 |
HOGENOMi | CLU_034170_0_0_1 |
OMAi | FEADTSY |
OrthoDBi | 1397106at2759 |
TreeFami | TF333204 |
Family and domain databases
InterProi | View protein in InterPro IPR022174, ARA70 IPR039947, NCoA-4 |
PANTHERi | PTHR17085, PTHR17085, 1 hit |
Pfami | View protein in Pfam PF12489, ARA70, 2 hits |
i Sequence
Sequence statusi: Complete.
B1H215-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNTSLEQSGC CSSRETLLRC SDARRELELA IGGVLRAEQQ MKDNLREVKA
60 70 80 90 100
QIHSCISRHL ECLRSREVWL NEQVDLIYQL KEETLQQQAQ QLYWLMGQFN
110 120 130 140 150
CLIHQLEITQ NKDLANQVAL CLERLGSLTL KPEDSTVLLF EADASALRQT
160 170 180 190 200
ITTFGSLKTI QIPEHLMAHP SSSSVRPFLE KRGYTQVPEQ KSASSGTAVS
210 220 230 240 250
LSEWLLVSKP AIGPQAPYVP STNPQDWLTP KQTLENSQTS ARICSDAWGN
260 270 280 290 300
LKGLENWLLN SHQQEIPGKP SSSKCNSHCS TSSFSTEDEK VEDVEVLDQD
310 320 330 340 350
ELDLSDWLVT PQEPRDLEKP VNGRSDTSDK FKLLFQVFRE PYNVNDWLVK
360 370 380 390 400
PDSCTNCQGN QPRGVEIENL GNLKCLNDHL EAKKSLPVPG VITEGWLVQN
410 420 430 440 450
HQDTCKVEEV CKANEPCTSF AECVCDDSCE KEAMHKWLLK KEGKDKNGMP
460 470 480 490 500
MGPKSESEKH RESLSLWLCP SRNELTEHAK TPKTTAPARI ADSFHIIRNS
510 520 530 540 550
SLSEWLIGPT CKGGGPKEVP NMEERASKEM LKSPMATYWR PFNTADWVLP
560 570 580 590 600
GKKVGNLSQF SSGEDKWLLR KKAQEVFLNS PLQEERNFRS DCYGLPAVCD
610 620
LFACMQLKVD KDKWLYRAPL QM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC129637 Genomic DNA No translation available. BC160817 mRNA Translation: AAI60817.1 CH474046 Genomic DNA Translation: EDL88925.1 CH474046 Genomic DNA Translation: EDL88926.1 |
RefSeqi | NP_001029179.1, NM_001034007.1 NP_001029180.1, NM_001034008.1 |
Genome annotation databases
Ensembli | ENSRNOT00000026803; ENSRNOP00000026803; ENSRNOG00000019768 ENSRNOT00000066062; ENSRNOP00000061299; ENSRNOG00000019768 |
GeneIDi | 619385 |
KEGGi | rno:619385 |
UCSCi | RGD:1563014, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC129637 Genomic DNA No translation available. BC160817 mRNA Translation: AAI60817.1 CH474046 Genomic DNA Translation: EDL88925.1 CH474046 Genomic DNA Translation: EDL88926.1 |
RefSeqi | NP_001029179.1, NM_001034007.1 NP_001029180.1, NM_001034008.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000061299 |
Genome annotation databases
Ensembli | ENSRNOT00000026803; ENSRNOP00000026803; ENSRNOG00000019768 ENSRNOT00000066062; ENSRNOP00000061299; ENSRNOG00000019768 |
GeneIDi | 619385 |
KEGGi | rno:619385 |
UCSCi | RGD:1563014, rat |
Organism-specific databases
CTDi | 8031 |
RGDi | 1563014, Ncoa4 |
Phylogenomic databases
eggNOGi | ENOG502QQ6V, Eukaryota |
GeneTreei | ENSGT00390000008403 |
HOGENOMi | CLU_034170_0_0_1 |
OMAi | FEADTSY |
OrthoDBi | 1397106at2759 |
TreeFami | TF333204 |
Gene expression databases
Bgeei | ENSRNOG00000019768, Expressed in duodenum and 20 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR022174, ARA70 IPR039947, NCoA-4 |
PANTHERi | PTHR17085, PTHR17085, 1 hit |
Pfami | View protein in Pfam PF12489, ARA70, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | B1H215_RAT | |
Accessioni | B1H215Primary (citable) accession number: B1H215 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 29, 2008 |
Last sequence update: | April 29, 2008 | |
Last modified: | January 19, 2022 | |
This is version 86 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |