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UniProtKB - B1H1D9 (B1H1D9_XENTR)

Entry version 72 (02 Dec 2020)
Sequence version 1 (29 Apr 2008)
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Protein
Submitted name:

Centrosomal protein 83kDa

Gene

cep83

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-XTR-5620912, Anchoring of the basal body to the plasma membrane

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Centrosomal protein 83kDaImported
Submitted name:
LOC100145346 proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:cep83Imported
Synonyms:ccdc41Imported, LOC100145346Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8364 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008143 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...Xenbasei		XB-GENE-952839, cep83

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSXETG00000023829, Expressed in female gonad and 12 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		8364.ENSXETP00000051366

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili31 – 97Sequence analysisAdd BLAST67
Coiled coili109 – 143Sequence analysisAdd BLAST35
Coiled coili159 – 186Sequence analysisAdd BLAST28
Coiled coili199 – 233Sequence analysisAdd BLAST35
Coiled coili245 – 300Sequence analysisAdd BLAST56
Coiled coili312 – 343Sequence analysisAdd BLAST32
Coiled coili380 – 407Sequence analysisAdd BLAST28
Coiled coili433 – 565Sequence analysisAdd BLAST133
Coiled coili567 – 594Sequence analysisAdd BLAST28
Coiled coili601 – 621Sequence analysisAdd BLAST21
Coiled coili656 – 683Sequence analysisAdd BLAST28

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QWE2, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000154003

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_020145_1_0_1

Identification of Orthologs from Complete Genome Data

More...OMAi		LNEKQTH

Database of Orthologous Groups

More...OrthoDBi		1094723at2759

TreeFam database of animal gene trees

More...TreeFami		TF329199

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.10, 7 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029631, Cep83
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR013105, TPR_2
IPR019734, TPR_repeat
IPR040364, TTC21A/TTC21B

The PANTHER Classification System

More...PANTHERi		PTHR14699, PTHR14699, 1 hit
PTHR23170:SF2, PTHR23170:SF2, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF07719, TPR_2, 1 hit
PF13174, TPR_6, 1 hit
PF13181, TPR_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00028, TPR, 16 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48452, SSF48452, 5 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50005, TPR, 11 hits
PS50293, TPR_REGION, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

B1H1D9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEILPQMSST LAVSAADTEL QKLLIDEQMR CEHHKTNYQT LKAEHTRLQD 
        60         70         80         90        100
EYIKSQNECK RLLMEKQNTQ EKVQLMLAEL RGELLDKTRE AEELKLKVLS 
       110        120        130        140        150
PQKLELLKIQ ILEEQEAPIK ERYRQLEEEA EKYRGDYNKL RYELTLLRAE 
       160        170        180        190        200
FDHQKEEHER VLQERRIKYE AEILQLEREK KELHDQIMSV DPTRDSKRVE 
       210        220        230        240        250
VLLREKAQLY QKLKSLEAET TELRAERENY GSQAENVQRI QVRQMAENQA 
       260        270        280        290        300
TIRSLEAEKQ SMKLQLERLE KELHESTEQN TILTAKLHKM EREVNALSSR 
       310        320        330        340        350
TGELKYSHKM EISNIKLEAA KTKNEVERER DKVQSQLDVM QTENGILKAT 
       360        370        380        390        400
LDRQKEILAE KDRELIRKVQ AAKEAGFQQI VTLQDERLQL ENRIAELERY 
       410        420        430        440        450
KVEHDSQKQT EISQIEEKLH IAQTAEESTR RELQSLRSKH QQQVSYIEQL 
       460        470        480        490        500
QKEKRDEEDL KQQINDLKIQ VTSLSESENS LLLANEKLRQ LVEQLKQENR 
       510        520        530        540        550
STRNQVEKTQ HNAEKELESN RIEWLQEKHK LQETLSELQD KYSQAKEKLQ 
       560        570        580        590        600
RAAAAQKKRK TLNENKCIKL QKKIELLEAT KEELEAQKHV LNRQNVPHEE 
       610        620        630        640        650
FGRLQKRLKD LQRRHNEFRS LILGPNISAS GLLNPVSFLS STVVPGADLS 
       660        670        680        690 
FINAQEEQHQ RELSLLRKRL EDLETTQRKQ LEELGPPIEG SQSM
Length:694
Mass (Da):81,919
Last modified:April 29, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4CE0468AE598F519
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A6I8QXC0A0A6I8QXC0_XENTR
Centrosomal protein 83kDa
cep83
688Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8SGN1A0A6I8SGN1_XENTR
Centrosomal protein 83kDa
cep83
578Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8RR94A0A6I8RR94_XENTR
Centrosomal protein 83kDa
cep83
692Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8RVW2A0A6I8RVW2_XENTR
Centrosomal protein 83kDa
cep83
694Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8SJN9A0A6I8SJN9_XENTR
Centrosomal protein 83kDa
cep83
519Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8QGW8A0A6I8QGW8_XENTR
Centrosomal protein 83kDa
cep83
694Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BC160570 mRNA Translation: AAI60570.1

NCBI Reference Sequences

More...RefSeqi		NP_001120290.1, NM_001126818.1
XP_012814028.1, XM_012958574.2
XP_012814029.1, XM_012958575.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSXETT00000051366; ENSXETP00000051366; ENSXETG00000023829

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100145346

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		xtr:100145346

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC160570 mRNA Translation: AAI60570.1
RefSeqiNP_001120290.1, NM_001126818.1
XP_012814028.1, XM_012958574.2
XP_012814029.1, XM_012958575.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000051366

Genome annotation databases

EnsembliENSXETT00000051366; ENSXETP00000051366; ENSXETG00000023829
GeneIDi100145346
KEGGixtr:100145346

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		51134
XenbaseiXB-GENE-952839, cep83

Phylogenomic databases

eggNOGiENOG502QWE2, Eukaryota
GeneTreeiENSGT00940000154003
HOGENOMiCLU_020145_1_0_1
OMAiLNEKQTH
OrthoDBi1094723at2759
TreeFamiTF329199

Enzyme and pathway databases

ReactomeiR-XTR-5620912, Anchoring of the basal body to the plasma membrane

Gene expression databases

BgeeiENSXETG00000023829, Expressed in female gonad and 12 other tissues

Family and domain databases

Gene3Di1.25.40.10, 7 hits
InterProiView protein in InterPro
IPR029631, Cep83
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR013105, TPR_2
IPR019734, TPR_repeat
IPR040364, TTC21A/TTC21B
PANTHERiPTHR14699, PTHR14699, 1 hit
PTHR23170:SF2, PTHR23170:SF2, 1 hit
PfamiView protein in Pfam
PF07719, TPR_2, 1 hit
PF13174, TPR_6, 1 hit
PF13181, TPR_8, 1 hit
SMARTiView protein in SMART
SM00028, TPR, 16 hits
SUPFAMiSSF48452, SSF48452, 5 hits
PROSITEiView protein in PROSITE
PS50005, TPR, 11 hits
PS50293, TPR_REGION, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB1H1D9_XENTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B1H1D9
Secondary accession number(s): A0A1P0Y8Y6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: December 2, 2020
This is version 72 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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