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Protein

Septin-8

Gene

sept8

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei104GTP; via amide nitrogenBy similarity1
Binding sitei239GTP; via amide nitrogen and carbonyl oxygenBy similarity1
Binding sitei254GTPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi49 – 56GTPBy similarity8
Nucleotide bindingi185 – 193GTPBy similarity9

GO - Molecular functioni

Keywordsi

LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Septin-8
Gene namesi
Name:sept8
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-1032907 sept8

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003632331 – 427Septin-8Add BLAST427

Proteomic databases

PRIDEiB1H120

Structurei

3D structure databases

ProteinModelPortaliB1H120
SMRiB1H120
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 305Septin-type GPROSITE-ProRule annotationAdd BLAST267

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni49 – 56G1 motifPROSITE-ProRule annotation8
Regioni101 – 104G3 motifPROSITE-ProRule annotation4
Regioni184 – 187G4 motifPROSITE-ProRule annotation4

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili321 – 409Sequence analysisAdd BLAST89

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOVERGENiHBG065093
InParanoidiB1H120
KOiK16939

Family and domain databases

CDDicd01850 CDC_Septin, 1 hit
InterProiView protein in InterPro
IPR030379 G_SEPTIN_dom
IPR027417 P-loop_NTPase
IPR030646 SEPT8
IPR016491 Septin
PANTHERiPTHR18884:SF54 PTHR18884:SF54, 1 hit
PfamiView protein in Pfam
PF00735 Septin, 1 hit
PIRSFiPIRSF006698 Septin, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51719 G_SEPTIN, 1 hit

Sequencei

Sequence statusi: Complete.

B1H120-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATDVERVS NEEKRSLAMT GHVGFDSLPD QLVSKSVTQG FCFNILCVGE
60 70 80 90 100
TGIGKSTLMN TLFNTTFETE EASHYENGVR LRPRTYDLQE SNVHLKLTIV
110 120 130 140 150
DTVGFGDQIN KDDSYRSVVD YIDTQFENYL QEELKIRRSL FNYHDSRIHV
160 170 180 190 200
CLYFITPTGH SLKSLDLVTM KKLDSKVNII PIIAKADTIS KSELHKFKIK
210 220 230 240 250
IMSELVSNGV QIYQFPTDDD AVAEINSVMN AHLPFAVVGS TEEVKVGNKL
260 270 280 290 300
VRARQYPWGV VQVENESHCD FVKLREMLIR VNMEDLREQT HTRHYELYRR
310 320 330 340 350
CKLEEMGFKD NDPDTQPFSL QETYEAKRKE FLGELQRKEE EMRQMFVNKV
360 370 380 390 400
KETEAELKDK ERELQEKFMQ LKRVHQEESK KVEDKRRDLE EEMNSFNRRK
410 420
AAMEALQSQS FQATSQQPLK KDKDRKN
Length:427
Mass (Da):49,764
Last modified:April 29, 2008 - v1
Checksum:iC398FE9A25904D88
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC160437 mRNA Translation: AAI60437.1
RefSeqiNP_001116199.1, NM_001122727.1
UniGeneiStr.55530

Genome annotation databases

GeneIDi100126684
KEGGixtr:100126684

Similar proteinsi

Entry informationi

Entry nameiSEPT8_XENTR
AccessioniPrimary (citable) accession number: B1H120
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: April 29, 2008
Last modified: June 20, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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