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Protein

Translation initiation factor IF-1

Gene

infA

Organism
Burkholderia ambifaria IOP40-10
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

GO - Molecular functioni

Keywordsi

Molecular functionInitiation factorUniRule annotationSAAS annotationImported, RNA-binding, rRNA-bindingUniRule annotationSAAS annotation
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-1UniRule annotation
Gene namesi
Name:infAUniRule annotation
ORF Names:BamIOP4010DRAFT_2654Imported
OrganismiBurkholderia ambifaria IOP40-10Imported
Taxonomic identifieri396596 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi
  • UP000005463 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliB1FF44
SMRiB1FF44
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 72S1-likeInterPro annotationAdd BLAST72

Sequence similaritiesi

Belongs to the IF-1 family.UniRule annotationSAAS annotation

Phylogenomic databases

OrthoDBiPOG091H019C

Family and domain databases

CDDicd04451 S1_IF1, 1 hit
HAMAPiMF_00075 IF_1, 1 hit
InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR006196 RNA-binding_domain_S1_IF1
IPR004368 TIF_IF1
PANTHERiPTHR33370 PTHR33370, 1 hit
PfamiView protein in Pfam
PF01176 eIF-1a, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00008 infA, 1 hit
PROSITEiView protein in PROSITE
PS50832 S1_IF1_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

B1FF44-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEELLELD GIVDEVLPDS KYRVTLENGV VVGAYASGRM RKNHIRILAG
60 70 80
DRVTLELSMY DLTKGRINFR HKDANSTRPP RSGQPRR
Length:87
Mass (Da):9,879
Last modified:April 29, 2008 - v1
Checksum:iD9B2F3FE54D69C20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABLC01000056 Genomic DNA Translation: EDT03855.1
RefSeqiWP_006751842.1, NZ_ABLC01000056.1

Genome annotation databases

EnsemblBacteriaiEDT03855; EDT03855; BamIOP4010DRAFT_2654
PATRICifig|396596.7.peg.5109

Entry informationi

Entry nameiB1FF44_9BURK
AccessioniPrimary (citable) accession number: B1FF44
Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: March 28, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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