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Protein
Submitted name:

U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

Gene

Zrsr2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri170 – 198C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri310 – 337C3H1-typePROSITE-ProRule annotationAdd BLAST28

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-72165 mRNA Splicing - Minor Pathway

Names & Taxonomyi

Protein namesi
Submitted name:
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2Imported
Gene namesi
Name:Zrsr2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:103287 Zrsr2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiB1B0E8
PeptideAtlasiB1B0E8
PRIDEiB1B0E8

PTM databases

iPTMnetiB1B0E8
PhosphoSitePlusiB1B0E8

Expressioni

Gene expression databases

BgeeiENSMUSG00000031370 Expressed in 284 organ(s), highest expression level in primary oocyte
ExpressionAtlasiB1B0E8 baseline and differential
GenevisibleiB1B0E8 MM

Structurei

3D structure databases

ProteinModelPortaliB1B0E8
SMRiB1B0E8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini170 – 198C3H1-typeInterPro annotationAdd BLAST29
Domaini202 – 308RRMInterPro annotationAdd BLAST107
Domaini310 – 337C3H1-typeInterPro annotationAdd BLAST28

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili27 – 54Sequence analysisAdd BLAST28
Coiled coili80 – 153Sequence analysisAdd BLAST74

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri170 – 198C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri310 – 337C3H1-typePROSITE-ProRule annotationAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2202 Eukaryota
ENOG410Z5PX LUCA
GeneTreeiENSGT00530000063193
HOGENOMiHOG000049279
HOVERGENiHBG054605
OMAiKHNYPTS
OrthoDBiEOG091G0CUI
TreeFamiTF324447

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR003954 RRM_dom_euk
IPR009145 U2AF_small
IPR000571 Znf_CCCH
PANTHERiPTHR12620 PTHR12620, 1 hit
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
PF00642 zf-CCCH, 1 hit
PRINTSiPR01848 U2AUXFACTOR
SMARTiView protein in SMART
SM00361 RRM_1, 1 hit
SM00356 ZnF_C3H1, 2 hits
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
PS50103 ZF_C3H1, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

B1B0E8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METAGATADA TAGPQKLSRK KYLALRKKER RKRRRQALAR LREAELAQKE
60 70 80 90 100
EEEDPLAEEK RLEEERLLEE ERQRLHEEWL LREEKAQEEF RAKKKKEEEA
110 120 130 140 150
RKRKEELERK LKAEWEEQQR KEREEEEQKR QEKREREEAV QKMLDQAENE
160 170 180 190 200
LENGGTWQNP EPPMDIRVLE KDRANCPFYS KTGACRFGDR CSRKHNFPTS
210 220 230 240 250
SPTLLIKGMF TTFGMEQCRR DDYDPDSSLE FSEEEIYQQF LDFYYDVLPE
260 270 280 290 300
FKSVGKVIQF KVSCNLEPHL RGNVYVQYQS EEDCQAAFSV FNGRWYAGRQ
310 320 330 340 350
LQCEFCPVTR WKMAICGLFE VQQCPRGKHC NFLHVFRNPN NEYRDANRDL
360 370 380 390 400
YPSPDWTSSS FGKNSERRER ASHYDEYYGR SRRRRRSPSP DFYKRNGESD
410 420 430 440 450
RKSSSRHRVK KSHRYGMKSR ERRSSPSRRR KDHSPGPWSQ SRRSHRSRSR
460 470 480 490 500
SRSRSRSRSR TRSRSRGRGR SRSRSRSRSR GRSRSRGRGS GRGRGRGRGR
510 520 530 540
GRNQSRSWSQ SRSRSSSSSR SRSRGRRSGS RDKTTQSPKS K
Length:541
Mass (Da):64,449
Last modified:April 8, 2008 - v1
Checksum:i2C6C0A4A99C47951
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q62377U2AFM_MOUSE
U2 small nuclear ribonucleoprotein ...
Zrsr2 U2af1-rs2, U2af1l2, U2af1rs2
462Annotation score:
B1B0E9B1B0E9_MOUSE
U2 small nuclear ribonucleoprotein ...
Zrsr2
144Annotation score:
B1B0F1B1B0F1_MOUSE
U2 small nuclear ribonucleoprotein ...
Zrsr2
71Annotation score:
B1B0F0B1B0F0_MOUSE
U2 small nuclear ribonucleoprotein ...
Zrsr2
113Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX469932 Genomic DNA No translation available.
RefSeqiNP_033479.2, NM_009453.3
XP_006528858.1, XM_006528795.3
XP_006528859.1, XM_006528796.3
UniGeneiMm.426178

Genome annotation databases

EnsembliENSMUST00000112289; ENSMUSP00000107908; ENSMUSG00000031370
GeneIDi22184
KEGGimmu:22184
UCSCiuc009uuz.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX469932 Genomic DNA No translation available.
RefSeqiNP_033479.2, NM_009453.3
XP_006528858.1, XM_006528795.3
XP_006528859.1, XM_006528796.3
UniGeneiMm.426178

3D structure databases

ProteinModelPortaliB1B0E8
SMRiB1B0E8
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiB1B0E8
PhosphoSitePlusiB1B0E8

Proteomic databases

MaxQBiB1B0E8
PeptideAtlasiB1B0E8
PRIDEiB1B0E8

Protocols and materials databases

DNASUi22184
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000112289; ENSMUSP00000107908; ENSMUSG00000031370
GeneIDi22184
KEGGimmu:22184
UCSCiuc009uuz.2 mouse

Organism-specific databases

CTDi8233
MGIiMGI:103287 Zrsr2

Phylogenomic databases

eggNOGiKOG2202 Eukaryota
ENOG410Z5PX LUCA
GeneTreeiENSGT00530000063193
HOGENOMiHOG000049279
HOVERGENiHBG054605
OMAiKHNYPTS
OrthoDBiEOG091G0CUI
TreeFamiTF324447

Enzyme and pathway databases

ReactomeiR-MMU-72165 mRNA Splicing - Minor Pathway

Miscellaneous databases

ChiTaRSiZrsr2 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031370 Expressed in 284 organ(s), highest expression level in primary oocyte
ExpressionAtlasiB1B0E8 baseline and differential
GenevisibleiB1B0E8 MM

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR003954 RRM_dom_euk
IPR009145 U2AF_small
IPR000571 Znf_CCCH
PANTHERiPTHR12620 PTHR12620, 1 hit
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
PF00642 zf-CCCH, 1 hit
PRINTSiPR01848 U2AUXFACTOR
SMARTiView protein in SMART
SM00361 RRM_1, 1 hit
SM00356 ZnF_C3H1, 2 hits
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
PS50103 ZF_C3H1, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiB1B0E8_MOUSE
AccessioniPrimary (citable) accession number: B1B0E8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 7, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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