UniProtKB - B1AVB3 (B1AVB3_MOUSE)
Protein
Submitted name:
Scm polycomb group protein-like 2
Gene
Scml2
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- chromatin binding Source: GO_Central
- histone binding Source: GO_Central
GO - Biological processi
- apoptotic process Source: MGI
- cellular protein localization Source: MGI
- histone H2A-K119 monoubiquitination Source: MGI
- negative regulation of transcription, DNA-templated Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Scm polycomb group protein-like 2Imported |
Gene namesi | Name:Scml2Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1340042, Scml2 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nuclear chromatin Source: MGI
- nucleus Source: MGI
Other locations
- XY body Source: MGI
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000000037, Expressed in zygote and 159 other tissues |
ExpressionAtlasi | B1AVB3, baseline and differential |
Interactioni
GO - Molecular functioni
- histone binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000076593 |
Miscellaneous databases
RNActi | B1AVB3, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 10 – 108 | MBTPROSITE-ProRule annotationAdd BLAST | 99 | |
Repeati | 116 – 217 | MBTPROSITE-ProRule annotationAdd BLAST | 102 | |
Domaini | 662 – 706 | RBRInterPro annotationAdd BLAST | 45 | |
Domaini | 736 – 845 | SLEDInterPro annotationAdd BLAST | 110 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 274 – 705 | DisorderedSequence analysisAdd BLAST | 432 | |
Regioni | 851 – 904 | DisorderedSequence analysisAdd BLAST | 54 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 293 – 327 | PolyampholyteSequence analysisAdd BLAST | 35 | |
Compositional biasi | 334 – 365 | PolyampholyteSequence analysisAdd BLAST | 32 | |
Compositional biasi | 376 – 393 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 404 – 421 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 435 – 449 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 460 – 477 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 488 – 505 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 519 – 533 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 544 – 561 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 572 – 598 | PolyampholyteSequence analysisAdd BLAST | 27 | |
Compositional biasi | 609 – 680 | PolarSequence analysisAdd BLAST | 72 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota KOG3766, Eukaryota |
GeneTreei | ENSGT00940000159407 |
InParanoidi | B1AVB3 |
TreeFami | TF106488 |
Family and domain databases
Gene3Di | 1.20.1380.20, 1 hit |
InterProi | View protein in InterPro IPR004092, Mbt IPR013761, SAM/pointed_sf IPR033763, SCML2_RBR IPR021987, SLED IPR038348, SLED_sf |
Pfami | View protein in Pfam PF02820, MBT, 2 hits PF17208, RBR, 1 hit PF12140, SLED, 1 hit |
SMARTi | View protein in SMART SM00561, MBT, 2 hits |
SUPFAMi | SSF47769, SSF47769, 1 hit |
PROSITEi | View protein in PROSITE PS51079, MBT, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
B1AVB3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGQTANEDHF DWDKYLKETG SISAPSEYFR QSKTPPTNEF KIGMKLEARD
60 70 80 90 100
PRNIDSVCVA SVIGITGARL RLRLDGSDNK NDFWRLVDSS DIQPVGTCEQ
110 120 130 140 150
GGDLLQPPLG YTLNTSSWPM FLLRVLTGSE LAPAVFFKEE PPRPLQNNFI
160 170 180 190 200
VGMKIEAVDR KNPFMICPAT IGAVCGDQLH ITFDGWSGAF DYWCDYDSRD
210 220 230 240 250
IFPVGWCRLT GDVLQPPGKI VEKRPRRKRR TRLWRLRTAL LGNEEEAPAA
260 270 280 290 300
EEPGTSVLTF GDENRTLKDC RGEAAEEPGT SAFTFGDENR TLKDCQGGWK
310 320 330 340 350
KPKGRGFIKP GKDETRPGKH DQGAPAGKKP RGRGFTQPLE DEARPGRDVQ
360 370 380 390 400
VAPAEKKRKG KTVTTPWTED PRLFADQGDA PAEKKRKGKT VTTPWTEDPR
410 420 430 440 450
LFADQGDAPA EKKRKGKTVT TPWTEDPRLF ADQGAAPAEK KRKGKTVTTP
460 470 480 490 500
WTEDPRLFAD QGDAPAEKKR KGKTVTTPWT EDPRLFADQG DAPAEKKRKG
510 520 530 540 550
KTVTTPWTED PRLFADQGAA PAEKKRKGKT VTTPWTEDPR LFADQGDAPA
560 570 580 590 600
EKKRKGKTVT TPWTEDPRLF ADQGDAPAEK KPKGKRVTKS RKDQAQFLAD
610 620 630 640 650
EEAMPALFSA LSVSSTERTP PSSSEQPKSS TSGKTKSTSR GAQTSRKSPR
660 670 680 690 700
KTSVVQPVPK TSKKAGKSKS TGNTSSPKKG ITIKIVLPKK KGGKSGKKEK
710 720 730 740 750
SIPVISSTSS ASLSTLMKSS SSNKTSAGPS KIVMSTVCVY INKHGDCGPF
760 770 780 790 800
LDPQKVQQLP NHFGPGPVNV ILQRTVQACV NCAFQAKDVF LFLKTDNRGG
810 820 830 840 850
EMITAFFDGK VHTVQLPPVN SASFALRFLE NFCQSLQCDN FLSSQPFRRE
860 870 880 890 900
AQVPTPDTGT DQSKPENGEP KEKRSLKRLS LHPHRSAPVS SKVPRKSGQA
910 920 930 940 950
SKASSYITVP DPSVLKQGFC KDPSTWSVDE VIQFMKHTDP QISGPLADLF
960
RQHVTYLLIR FSCCPNASK
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketB1AVB5 | B1AVB5_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 905 | Annotation score: | ||
B1AVB4 | B1AVB4_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 845 | Annotation score: | ||
E9Q796 | E9Q796_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 901 | Annotation score: | ||
B1AVB2 | B1AVB2_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 827 | Annotation score: | ||
A0A571BDL9 | A0A571BDL9_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 367 | Annotation score: | ||
A0A571BGE2 | A0A571BGE2_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 130 | Annotation score: | ||
B1AVB1 | B1AVB1_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 825 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL670462 Genomic DNA No translation available. AL672233 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000077375; ENSMUSP00000076593; ENSMUSG00000000037 |
UCSCi | uc009utw.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL670462 Genomic DNA No translation available. AL672233 Genomic DNA No translation available. |
3D structure databases
SMRi | B1AVB3 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000076593 |
Proteomic databases
MaxQBi | B1AVB3 |
PeptideAtlasi | B1AVB3 |
PRIDEi | B1AVB3 |
Protocols and materials databases
Antibodypediai | 475, 168 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000077375; ENSMUSP00000076593; ENSMUSG00000000037 |
UCSCi | uc009utw.2, mouse |
Organism-specific databases
MGIi | MGI:1340042, Scml2 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota KOG3766, Eukaryota |
GeneTreei | ENSGT00940000159407 |
InParanoidi | B1AVB3 |
TreeFami | TF106488 |
Miscellaneous databases
ChiTaRSi | Scml2, mouse |
RNActi | B1AVB3, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000000037, Expressed in zygote and 159 other tissues |
ExpressionAtlasi | B1AVB3, baseline and differential |
Family and domain databases
Gene3Di | 1.20.1380.20, 1 hit |
InterProi | View protein in InterPro IPR004092, Mbt IPR013761, SAM/pointed_sf IPR033763, SCML2_RBR IPR021987, SLED IPR038348, SLED_sf |
Pfami | View protein in Pfam PF02820, MBT, 2 hits PF17208, RBR, 1 hit PF12140, SLED, 1 hit |
SMARTi | View protein in SMART SM00561, MBT, 2 hits |
SUPFAMi | SSF47769, SSF47769, 1 hit |
PROSITEi | View protein in PROSITE PS51079, MBT, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B1AVB3_MOUSE | |
Accessioni | B1AVB3Primary (citable) accession number: B1AVB3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 8, 2008 |
Last sequence update: | April 8, 2008 | |
Last modified: | February 10, 2021 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |