UniProtKB - B1AVB1 (B1AVB1_MOUSE)
Protein
Submitted name:
Scm polycomb group protein-like 2
Gene
Scml2
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- chromatin binding Source: GO_Central
- histone binding Source: GO_Central
GO - Biological processi
- apoptotic process Source: MGI
- cellular protein localization Source: MGI
- histone H2A-K119 monoubiquitination Source: MGI
- negative regulation of transcription, DNA-templated Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Scm polycomb group protein-like 2Imported |
Gene namesi | Name:Scml2Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1340042, Scml2 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nuclear chromatin Source: MGI
- nucleus Source: MGI
Other locations
- XY body Source: MGI
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000000037, Expressed in zygote and 159 other tissues |
ExpressionAtlasi | B1AVB1, baseline and differential |
Family & Domainsi
Phylogenomic databases
GeneTreei | ENSGT00940000159407 |
HOGENOMi | CLU_343200_0_0_1 |
OMAi | ATVMGMT |
Family and domain databases
Gene3Di | 1.20.1380.20, 1 hit |
InterProi | View protein in InterPro IPR004092, Mbt IPR033763, SCML2_RBR IPR021987, SLED IPR038348, SLED_sf |
Pfami | View protein in Pfam PF02820, MBT, 2 hits PF17208, RBR, 1 hit PF12140, SLED, 1 hit |
SMARTi | View protein in SMART SM00561, MBT, 2 hits |
PROSITEi | View protein in PROSITE PS51079, MBT, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
B1AVB1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAEPATGVQL AGSGELVAEP GPSSTEAREP ATAEGTSGLG QQVTKQGHPS
60 70 80 90 100
TGEMEPATGV QLAGSGELVA EPGPSSTEAR ENTEEANTMG QTANEDHFDW
110 120 130 140 150
DKYLKETGSI SAPSEYFRQS KTPPTNEFKI GMKLEARDPR NIDSVCVASV
160 170 180 190 200
IGITGARLRL RLDGSDNKND FWRLVDSSDI QPVGTCEQGG DLLQPPLGYT
210 220 230 240 250
LNTSSWPMFL LRVLTGSELA PAVFFKEEPP RPLQNNFIVG MKIEAVDRKN
260 270 280 290 300
PFMICPATIG AVCGDQLHIT FDGWSGAFDY WCDYDSRDIF PVGWCRLTGD
310 320 330 340 350
VLQPPGKIVE KRPRRKRRTR LWRLRTALLG NEEEAPEAAE EPGTSVLTFG
360 370 380 390 400
DENRTLKDCR GEAAEEPGTS AFTFGDENRT LKDCQGGWKK PKGRGFIKPG
410 420 430 440 450
KDETRPGKHD QGAPAGKKPR GRGFTQPLED EARPGRDVQV APAEKKRKGK
460 470 480 490 500
TVTTPWTEDP RLFADQGDAP AEKKRKGKTV TTPWTEDPRL FADQGDAPAE
510 520 530 540 550
KKPKGKRVTK SRKDQAQFLA DEEAMPALFS ALSVSSTERT PPSSSEQPKS
560 570 580 590 600
STSGKTKSTS RGAQTSRKSP RKTSVVQPVP KTSKKAGKSK STGNTSSPKK
610 620 630 640 650
GITIKIVLPK KKGGKSGKKE KSIPVISSTS SASLSTLMKS SSSNKTSAGP
660 670 680 690 700
SKIVMSTVCV YINKHGDCGP FLDPQKVQQL PNHFGPGPVN VILQRTVQAC
710 720 730 740 750
VNCAFQAKDV FLFLKTDNRG GEMITAFFDG KVHTVQLPPV NSASFALRFL
760 770 780 790 800
ENFCQSLQCD NFLSSQPFRR EAQVPTPDTG TDQSKPENGE PKEKRSLKRL
810 820
SLHPHRSAPV SSKVPRKSGQ ASKGN
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketB1AVB3 | B1AVB3_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 969 | Annotation score: | ||
B1AVB5 | B1AVB5_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 905 | Annotation score: | ||
B1AVB4 | B1AVB4_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 845 | Annotation score: | ||
E9Q796 | E9Q796_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 901 | Annotation score: | ||
B1AVB2 | B1AVB2_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 827 | Annotation score: | ||
A0A571BDL9 | A0A571BDL9_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 367 | Annotation score: | ||
A0A571BGE2 | A0A571BGE2_MOUSE | Scm polycomb group protein-like 2 | Scml2 | 130 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL670462 Genomic DNA No translation available. AL672233 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000101113; ENSMUSP00000098672; ENSMUSG00000000037 |
UCSCi | uc009utu.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL670462 Genomic DNA No translation available. AL672233 Genomic DNA No translation available. |
3D structure databases
SMRi | B1AVB1 |
ModBasei | Search... |
Proteomic databases
MaxQBi | B1AVB1 |
PeptideAtlasi | B1AVB1 |
Protocols and materials databases
Antibodypediai | 475, 168 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000101113; ENSMUSP00000098672; ENSMUSG00000000037 |
UCSCi | uc009utu.1, mouse |
Organism-specific databases
MGIi | MGI:1340042, Scml2 |
Phylogenomic databases
GeneTreei | ENSGT00940000159407 |
HOGENOMi | CLU_343200_0_0_1 |
OMAi | ATVMGMT |
Miscellaneous databases
ChiTaRSi | Scml2, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000000037, Expressed in zygote and 159 other tissues |
ExpressionAtlasi | B1AVB1, baseline and differential |
Family and domain databases
Gene3Di | 1.20.1380.20, 1 hit |
InterProi | View protein in InterPro IPR004092, Mbt IPR033763, SCML2_RBR IPR021987, SLED IPR038348, SLED_sf |
Pfami | View protein in Pfam PF02820, MBT, 2 hits PF17208, RBR, 1 hit PF12140, SLED, 1 hit |
SMARTi | View protein in SMART SM00561, MBT, 2 hits |
PROSITEi | View protein in PROSITE PS51079, MBT, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B1AVB1_MOUSE | |
Accessioni | B1AVB1Primary (citable) accession number: B1AVB1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 8, 2008 |
Last sequence update: | April 8, 2008 | |
Last modified: | October 7, 2020 | |
This is version 98 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |