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Entry version 106 (11 Dec 2019)
Sequence version 1 (08 Apr 2008)
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Protein
Submitted name:

Microtubule-actin cross-linking factor 1

Gene

Macf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi7013 – 7024PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi7049 – 7060PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingSAAS annotation
LigandCalciumPROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Microtubule-actin cross-linking factor 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Macf1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:108559 Macf1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonPROSITE-ProRule annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
B1ARU4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
B1ARU4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
B1ARU4

PeptideAtlas

More...
PeptideAtlasi
B1ARU4

PRoteomics IDEntifications database

More...
PRIDEi
B1ARU4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000028649 Expressed in 318 organ(s), highest expression level in lung

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
B1ARU4 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
B1ARU4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini78 – 181Calponin-homology (CH)InterPro annotationAdd BLAST104
Domaini194 – 298Calponin-homology (CH)InterPro annotationAdd BLAST105
Domaini868 – 925SH3InterPro annotationAdd BLAST58
Domaini7000 – 7035EF-handInterPro annotationAdd BLAST36
Domaini7036 – 7071EF-handInterPro annotationAdd BLAST36
Domaini7076 – 7154GARInterPro annotationAdd BLAST79

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 47DisorderedSequence analysisAdd BLAST47
Regioni2120 – 2155DisorderedSequence analysisAdd BLAST36
Regioni2806 – 2841DisorderedSequence analysisAdd BLAST36
Regioni2951 – 2974DisorderedSequence analysisAdd BLAST24
Regioni3058 – 3095DisorderedSequence analysisAdd BLAST38
Regioni6903 – 6934DisorderedSequence analysisAdd BLAST32
Regioni7170 – 7353DisorderedSequence analysisAdd BLAST184

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili245 – 265Sequence analysisAdd BLAST21
Coiled coili477 – 497Sequence analysisAdd BLAST21
Coiled coili502 – 529Sequence analysisAdd BLAST28
Coiled coili821 – 841Sequence analysisAdd BLAST21
Coiled coili1046 – 1066Sequence analysisAdd BLAST21
Coiled coili1403 – 1433Sequence analysisAdd BLAST31
Coiled coili1522 – 1542Sequence analysisAdd BLAST21
Coiled coili3355 – 3382Sequence analysisAdd BLAST28
Coiled coili3406 – 3426Sequence analysisAdd BLAST21
Coiled coili3656 – 3683Sequence analysisAdd BLAST28
Coiled coili3809 – 3847Sequence analysisAdd BLAST39
Coiled coili4074 – 4101Sequence analysisAdd BLAST28
Coiled coili4108 – 4128Sequence analysisAdd BLAST21
Coiled coili4148 – 4175Sequence analysisAdd BLAST28
Coiled coili4186 – 4206Sequence analysisAdd BLAST21
Coiled coili4214 – 4241Sequence analysisAdd BLAST28
Coiled coili4254 – 4281Sequence analysisAdd BLAST28
Coiled coili4319 – 4339Sequence analysisAdd BLAST21
Coiled coili4582 – 4602Sequence analysisAdd BLAST21
Coiled coili4696 – 4716Sequence analysisAdd BLAST21
Coiled coili4789 – 4809Sequence analysisAdd BLAST21
Coiled coili4833 – 4853Sequence analysisAdd BLAST21
Coiled coili4940 – 4995Sequence analysisAdd BLAST56
Coiled coili5132 – 5152Sequence analysisAdd BLAST21
Coiled coili5158 – 5178Sequence analysisAdd BLAST21
Coiled coili5813 – 5833Sequence analysisAdd BLAST21
Coiled coili6046 – 6073Sequence analysisAdd BLAST28
Coiled coili6825 – 6845Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi8 – 28PolyampholyteSequence analysisAdd BLAST21
Compositional biasi2141 – 2155PolyampholyteSequence analysisAdd BLAST15
Compositional biasi2810 – 2837PolyampholyteSequence analysisAdd BLAST28
Compositional biasi3079 – 3094PolyampholyteSequence analysisAdd BLAST16
Compositional biasi7189 – 7263PolarSequence analysisAdd BLAST75
Compositional biasi7300 – 7353PolarSequence analysisAdd BLAST54

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0516 Eukaryota
COG5069 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155824

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000049054

Database for complete collections of gene phylogenies

More...
PhylomeDBi
B1ARU4

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014 CH, 2 hits
cd00051 EFh, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 2 hits
3.30.920.20, 1 hit
3.90.1290.10, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR041615 Desmoplakin_SH3
IPR041573 Desmoplakin_Spectrin-like
IPR029926 Dystonin-like
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR003108 GAR_dom
IPR036534 GAR_dom_sf
IPR035915 Plakin_repeat_sf
IPR001101 Plectin_repeat
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat

The PANTHER Classification System

More...
PANTHERi
PTHR23169:SF24 PTHR23169:SF24, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307 CH, 2 hits
PF13499 EF-hand_7, 1 hit
PF02187 GAS2, 1 hit
PF00681 Plectin, 8 hits
PF17902 SH3_10, 1 hit
PF00435 Spectrin, 18 hits
PF18373 Spectrin_like, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033 CH, 2 hits
SM00054 EFh, 2 hits
SM00243 GAS2, 1 hit
SM00250 PLEC, 19 hits
SM00150 SPEC, 34 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF143575 SSF143575, 1 hit
SSF47473 SSF47473, 1 hit
SSF47576 SSF47576, 1 hit
SSF75399 SSF75399, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS00020 ACTININ_2, 1 hit
PS50021 CH, 2 hits
PS00018 EF_HAND_1, 2 hits
PS50222 EF_HAND_2, 2 hits
PS51460 GAR, 1 hit
PS50002 SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 18 potential isoforms that are computationally mapped.Show allAlign All

B1ARU4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSSDEETLS ERSCRSERSC RSERSYRSER SGSLSPCPPG DTLPWNLPLH
60 70 80 90 100
EQKKRKSQDS VLDPAERAVV RVADERDRVQ KKTFTKWVNK HLMKVRKHIN
110 120 130 140 150
DLYEDLRDGH NLISLLEVLS GIKLPREKGR MRFHRLQNVQ IALDFLKQRQ
160 170 180 190 200
VKLVNIRNDD ITDGNPKLTL GLIWTIILHF QISDIYISGE SGDMSAKEKL
210 220 230 240 250
LLWTQKVTAG YTGVKCTNFS SCWSDGKMFN ALIHRYRPDL VDMERVQVQS
260 270 280 290 300
NRENLEQAFE VAERLGVTRL LDAEDVDVPS PDEKSVITYV SSIYDAFPKV
310 320 330 340 350
PEGGEGISAT EVDSRWQEYQ SRVDSLIPWI RQHTILMSDK SFPQNPVELK
360 370 380 390 400
ALYNQYIHFK ETEILAKERE KGRIKELYKL LEVWIEFGRI KLPQGYHPNH
410 420 430 440 450
VEEEWGKLIV EMLEREKSLR PAVERLELLL QIANKIQNGA LNCEEKLTLA
460 470 480 490 500
KNTLQADAAH LESGQPVQCE SDVIMYIQEC EGLIRQLQVD LQILRDEKYY
510 520 530 540 550
QLEELAFRVM RLQDELVTLR LECTNLYRKG HFSSLELVPP STLTTTHLKA
560 570 580 590 600
EPLNKTTHSS STSWFRKPMT RTELVSISSS EDEGNLRFVY ELLSWVEEMQ
610 620 630 640 650
MKLERAEWGN DLPSVELQLE TQQHIHTSVE ELGSSVKEAR LYEGKMSQNF
660 670 680 690 700
HTSYVETLGK LETQYCKLKE TSSFRMRHLQ SLHKFVSRAT AELIWLNGKE
710 720 730 740 750
EEELACDWSD SNPNISAKKT YFSELTMELE GKQDVFRSLQ DTAEVLSLEN
760 770 780 790 800
HPAKQTVEAY SAAVQSQLQW MKQLCLCVEQ HVKENAAYFQ FFSDARDLES
810 820 830 840 850
FLRNLQDSIK RKYTCDRSTS LSRLEDLLQD SMDEKEQLIQ SKSSVASLVG
860 870 880 890 900
RSKTIVQLKP RNPDHVLKST LSVKAICDYR QIEITICKND ECVLEDNSQR
910 920 930 940 950
TKWKVISPTG NEAMVPSVCF LIPPPNKEAI EMASRVEQSY QKVMALWHQL
960 970 980 990 1000
HINTKSLISW NYLRKDLDTV QTWSLEKLRS LAPGECHQVM KNLQAHYEDF
1010 1020 1030 1040 1050
LQDSHDSALF SVADRLRIEE EVEACKAHFQ HLMKSLENED KEETLAKVYI
1060 1070 1080 1090 1100
SELKNIRLLL EECEQRLLKQ IQSPASSKTD RDARQDITLR IAEQEHTQED
1110 1120 1130 1140 1150
LQHLRSDLDA ISMKCNVFLQ QSPSGSSATT LRSELNLMVE KMDHVYGLST
1160 1170 1180 1190 1200
VYLNKLKTID VIVRSMQDAE LLVKGYEIKL SQEEAVPADL SALESHRTTL
1210 1220 1230 1240 1250
QHWLSDVKDK NSVFSVLDEE ITKAKKVAEQ LRHPASEPNL DLERYQEKGS
1260 1270 1280 1290 1300
QLQERWHRVI AQLETRQSEV ESIQEVLRDY RACHGTLIKW IEETTAQQEM
1310 1320 1330 1340 1350
MKPGQAEDSR VLSEQLSQQT ELFAEIERNQ TKLDQCQKFS QQYSTIVKDY
1360 1370 1380 1390 1400
ELQLMTYKAF VESQQKSPGK RRRMISSSDA ITQEFMDLRT RYTALVTLTT
1410 1420 1430 1440 1450
QHVKYISDAL RRLEEEEKVV EEEKQEHVEK VKDLLGWVST LARNTQGTTT
1460 1470 1480 1490 1500
SSHTSASADI EKAILEQQVL AEELTTKKEQ VSEAIKTSQI FLAKHGHKLS
1510 1520 1530 1540 1550
EGEKEQISEQ LRVLNKTYHD LCDGSANQLQ QLQSELAQQT EQKGCRAVAG
1560 1570 1580 1590 1600
VIDLGTVEIF PIFRAMQKGL IDQDTGLVLL ESQIIMSGLI DPENSEKLSL
1610 1620 1630 1640 1650
EEGLTRNFIN LPIYQQLLGL RDSLSLVSRL TGTLGSLSVV EAIEKKIISE
1660 1670 1680 1690 1700
RLGLKVLEVH LATGGFSLPP SENCINLEEA FHQGFIASSL HSELQSHLRS
1710 1720 1730 1740 1750
SKNLIDPNTA EKVGLLDLMQ RCIIHQESGL KLLPVKQLAG GMVSLKSGRK
1760 1770 1780 1790 1800
VSIFRAVQEG LIDRQVTVRL LEAQLFAGGI VDPRTGHRLT VEEAVRHNLI
1810 1820 1830 1840 1850
DQDMACAILI RQLQTGGIID TVTGDRMTID EAVTNNLVAA KIALVILESL
1860 1870 1880 1890 1900
WSFMGLLLPE SGEILPITDA LEQGIVSTEL AHKILHNRQQ IEALFLPTLT
1910 1920 1930 1940 1950
EIWSWEKATE SGILDKDLVN NLRSVCIPDM MPHIQLADSA EQSKVGFAAG
1960 1970 1980 1990 2000
KPPVSGPREE GSSHGEKLLF QLMTHSYIHA HTGQRLLLLD QELVEMLTSR
2010 2020 2030 2040 2050
DDCQVILPEV FEIQHQRLNT SEALQELYTG TISQISSAKH PRKPCESQFL
2060 2070 2080 2090 2100
SQNKDYPSQE NCTEAKGERS VVGIECSPAE SPERELFLKE QEAIIENVGS
2110 2120 2130 2140 2150
LKVINKVKLK LQRPLLGSRK EEQAETLREE NISGDPLLVE CPEESEGKDL
2160 2170 2180 2190 2200
STEKSKCQTP TKCSFTCHKE QVKTIKDIPS ETGTSLIKSQ NQMSQFQVDT
2210 2220 2230 2240 2250
SVGLRSEFKS EHDMNVNSLE KELKEELLVK DGHKQSQEGQ SVADGQTVAL
2260 2270 2280 2290 2300
EKTDTEDNAD EPALLHSSPF EDATLSTLSA QLQDGGIFNE ETGQKLLLNE
2310 2320 2330 2340 2350
AIAQGLVSSH TAVKLMGKLN MFRGFFDSQT CESLTTEEVI DEGLMDEKLL
2360 2370 2380 2390 2400
YNVLMSDKAI SGILDPRTHS LCSVKEAVAA GLLDKETATR ILEGQVITGG
2410 2420 2430 2440 2450
IVDLKRGKKL SVTLASNLGL VDTADQTELI NLEKATKGRG AEKAVKERLI
2460 2470 2480 2490 2500
ELQMETAGLM DPESKAPLTV LQSIDRGILE REAAVYLLTK QVLDGGIIHH
2510 2520 2530 2540 2550
ISGLRLSVDN AFKHGLIGED MARQLRKVEN FIHYQFFHPQ TKEALSFSEA
2560 2570 2580 2590 2600
IKLDLVSPDL KREIQEIQDF SGNLGDFIYG QKLTLAKTNK EESLANKTEL
2610 2620 2630 2640 2650
PSGVMHGVID PENCTIIPYS ELVKKCRIDT ESGWRYLEVI PFSDIKDEAG
2660 2670 2680 2690 2700
NNVLTPPEAI QLGKVDFASA LKVLEAQANT GGIIDMATGK RVTLASALEK
2710 2720 2730 2740 2750
KLLDENMARI IASHQMLSGG IIDIYSDQRV TLNDAVEKRL ISPELAAMIQ
2760 2770 2780 2790 2800
VDPLAEQGGT GVCELKGDFL RKELLSESSK TPRESYSKEK HEAVLQAGSL
2810 2820 2830 2840 2850
CAPEKAGIRG SNGEKAEKGR KISVEMEGQR QDEKASSDNK VSASILSPFG
2860 2870 2880 2890 2900
FEGESSYQVS VTHPCSESCD LKPREETRSC MKKCAVVERD KVVTQIKMVS
2910 2920 2930 2940 2950
HVKQSTSGLD AEEARERQGR MVSKEQGSHY ETAGNLLSER SVRVDRRVRR
2960 2970 2980 2990 3000
EMGGEQSVQM SREAAVLSEE ELDQEVTIGD EPDSFVKSQS MKMIGNDKGK
3010 3020 3030 3040 3050
EAGIEKDISV VCKIEGFPSQ MTSKDASLTN QDALPFYTEG ETKTVNLCSI
3060 3070 3080 3090 3100
LKPGEKLSQE TASTVQKEPL SSEIPRPERL NSQESDEEPQ ISDVPHISKG
3110 3120 3130 3140 3150
DMAAQITTRQ ETTDVQDLYI TSKSSETKDK IFPSKNYIEK LHQEIPMDPT
3160 3170 3180 3190 3200
RSHKLKEATI STLETEGISY LDSSDIKSLC EDSKADHKSC GHQKSKVTTT
3210 3220 3230 3240 3250
QAKKSLEVVD LLVRDTEEGS SEDRVGQRGP RVLASLLPEK LPTRTVQSEN
3260 3270 3280 3290 3300
IRQHDAVIPA ISEIREEMAL SLPCSVVKVD GKIPKEKHKE ILGDEQGPFM
3310 3320 3330 3340 3350
AIPSGKGIEG VNPEPCRATQ NVFTRRLCLE HDEKLVSYLS LLRDIEMRTK
3360 3370 3380 3390 3400
QIQPLELNVA ELQDLLGQAK ELDRELKDLS TVVSQELECV DRIVISQPQE
3410 3420 3430 3440 3450
VPAQLLKALE KDAKNLQKSL DSVSDSWSSR FLHLQSAVEV KKATVLNRHK
3460 3470 3480 3490 3500
ELQGKLQDLR AWVGRASLTL NSKGCDTETD ADSLSHTLQP YKDMKQSMAE
3510 3520 3530 3540 3550
RKSQLDALAL DIQLFISEHP QDLSLQQNQE MLQFLSELQR SFQGLVEHTA
3560 3570 3580 3590 3600
AQKDVVQGHL QQVQQEVQVK TLQKQQDTCH KKLEDLCNWV GQAERALERH
3610 3620 3630 3640 3650
QGGASRQELP ALQQNQSDLK DLQGDIQSHS TSFATAVKDI EGFLEENQTK
3660 3670 3680 3690 3700
LSPQELTALR EKLHQAKEQY EVLQERTRVA QKELEEAVTS ALQQETEKSK
3710 3720 3730 3740 3750
AATELAENKR KIDALLDWVA SVGSSERKPQ ASLPGMEQFS GACLEKQTLA
3760 3770 3780 3790 3800
ATDGHVDVNQ VPETLDRQYE LMKARHQELL SQQQNFIVAT QSVQSFLDQH
3810 3820 3830 3840 3850
SHNLTPEERQ KLQEKLGELK EQYAASLARS EAELKQTQAL RDELQKFLQD
3860 3870 3880 3890 3900
HKEFENWLQQ SENELDSMHK GGSSPEALNS LLKRQGSFSE DVISHKGDLR
3910 3920 3930 3940 3950
FVTISGQKVL ETENNFEEGQ EPSATRNLVN EKLKDATERY TTLHSKCIRL
3960 3970 3980 3990 4000
GSHLSMLLGQ YQQFQSSADS LQAWVLTCEA SVGKLLSDTV ASDPGVLQQQ
4010 4020 4030 4040 4050
LATTKQLQEE LAEHQVPVEK LQKAAHDLLD IEGEPALDCR PIQETTDSIS
4060 4070 4080 4090 4100
SRFQNLSCSL DERSALLQKA IAQSQSVQES MESLLQSIRE VEQNLERDQV
4110 4120 4130 4140 4150
ASLSSGVIQE ALANNMKLKQ DIARQKSSLE ATHDMVTRFM ETADSNSASV
4160 4170 4180 4190 4200
LQGKLAELSQ RFQQLQLQQQ EKESNLKKLL PQAEMFEQLS NKLQQFMENK
4210 4220 4230 4240 4250
SRLLASGNQP DQDIAHFSQQ IQELTLAMED QKENLDTLEH LVTTLGSCGF
4260 4270 4280 4290 4300
ALDLSQHQDK IQNLKKDFTE LQKTVQEREK DASTCQEQLD EFRKLIRTFQ
4310 4320 4330 4340 4350
KWLKETEGNV PPAKTFVSAK ELEKQIEHLK DLISDWESKG ALLGEINAKG
4360 4370 4380 4390 4400
TALESLIMDI TAPDSQAKTG SILPPVGSSV GSVNGYHTCK DLTEIQCDMF
4410 4420 4430 4440 4450
DVNSKYEKLW EVLRERQESL QTVFSRMEEV QKEASSVLQW LESKEEVLKA
4460 4470 4480 4490 4500
MDATLSPTKT ETVKAQAESN KAFLAELEQN SPKIQKVKEA LAGLLKTYPN
4510 4520 4530 4540 4550
SQEAENWKKM QEDLNSRWEK ATEVTVARQK QLEESASHLA CFQAAESQLR
4560 4570 4580 4590 4600
PWLMEKELMM GVLGPLSIDP NMLNAQKQQF MLKEFEARRQ QHEQLNEAAQ
4610 4620 4630 4640 4650
GILTGPGDMS PSASQVHKDL QSISQKWVEL TDKLNSRSSQ IDQAIVKSTQ
4660 4670 4680 4690 4700
YQDLLQDLSE KVKAIGQRLS GQSAISTQPE AVKQQLEETS EIRSDLGQLD
4710 4720 4730 4740 4750
NEIKEAQTLC QELSLLIGEQ YLKDELKKRL ETVALPLQGL EDLAADRMNR
4760 4770 4780 4790 4800
LQAALASTQQ FQQMFDELRT WLDEKQSQQA KNCPISAKLE RLQCQLQENE
4810 4820 4830 4840 4850
EFQKNLNQHS GSYEVIVAEG EALLLSVPPG EEKKTLQNQL VELRSHWEDL
4860 4870 4880 4890 4900
SKKTANRQSR LKDCMQKAQK YQGHVEDLVP WIDECKSKMS ELQVTLDPVQ
4910 4920 4930 4940 4950
LESSLLRSKA MLNEAEKRRS LLEILNSAAD ILINSSEIDE DEIRDEKAGL
4960 4970 4980 4990 5000
NQNMDAITEE LQAKTSSLEE MTQRLKEFQE SFKNIEKKVE GAKHQLEIFD
5010 5020 5030 5040 5050
ALGSQACSNK NLEKLKAQQE VLQALEPQVD YLRNFTQGLV EDAPDGSDAS
5060 5070 5080 5090 5100
PLVHQAEVAQ QEFLEVKQRV SSSCLTMENK LEGIGQFHCR VREMFSQLAD
5110 5120 5130 5140 5150
LDDELDGMGA IGRDTDSLQS QIEDVRLFLN KIQALRFDIE DSEAECRKML
5160 5170 5180 5190 5200
EEEGTLDLLG LKRELEALNK QCGKLTERGK VRQEQLELTL GRVEDFYRKL
5210 5220 5230 5240 5250
KALNDAATAA EEGEALQWIV GTEVDVINQQ LADFKLFQKD QVDPLQVKLQ
5260 5270 5280 5290 5300
QVNGLGQGLI QSAGKNCDVQ GLEHDMDEIN TRWNTLNKKV AQRIAQLQEA
5310 5320 5330 5340 5350
LLHCGKFQDA LEPLLSWLTD TEELIANQKP PSAEYKVVKA QIQEQKLLQR
5360 5370 5380 5390 5400
LLDDRKATVD MLQAEGGRIA QSAELADREK ITGQLESLER RWTDLLSKAA
5410 5420 5430 5440 5450
ARQKQLEDIL VLAKQFHETA EPISDFLSVT EKKLANSEPV GTQTAKIHQQ
5460 5470 5480 5490 5500
IIRHKALNEE IINRKKNVDQ AIKNGQALLK QTTGEEVLLI QEKLDGIKTR
5510 5520 5530 5540 5550
YADITLTSSK ALRTLEQARQ LATKFHSTYE ELTGWLREAE EELAASGGQS
5560 5570 5580 5590 5600
PTGEQIPQFQ QRQKELKKEV MEHRLVLDTV NEVSHALLEL VPWRAREGLD
5610 5620 5630 5640 5650
KLVSDANEQY KLISDTVGQR VDEIDAAIQR SQQYEQAADA ELAWVAETKR
5660 5670 5680 5690 5700
KLMALGPIRL EQDQTTAQLQ VQKAFSIDII RHKDSMDELF SHRGEIFSTC
5710 5720 5730 5740 5750
GEEQKAVLQE KTECLIQQYE AVSLLNSERY ARLERAQVLV NQFWETYEEL
5760 5770 5780 5790 5800
SPWAEETLAL IAQLPPPAVD HEQLRQQQEE MRQLRESIAE HKPHIDKILK
5810 5820 5830 5840 5850
IGPQLKELNP EEGKMVEEKY QKAENMYAQI KDEVRQRALA LDEAVSQSAQ
5860 5870 5880 5890 5900
FHDKIEPMLE TLENLSSRLR MPPLIPAEVD KIRECISDNK SATVELEKLQ
5910 5920 5930 5940 5950
PSFEALKRRG EELIGRSQGA DKDLAAKEIQ DKLDQMVFFW EDIKARSEER
5960 5970 5980 5990 6000
EIKFLDVLEL AEKFWYDMAA LLTTIKDTQD IVHDLESPGI DPSIIKQQVE
6010 6020 6030 6040 6050
AAETIKEETD GLHEELEFIR ILGADLIFAC GETEKPEVKK SIDEMNNAWE
6060 6070 6080 6090 6100
NLNKTWKERL EKLEDAMQAA VQYQDTLQAM FDWLDNTVIK LCTMPPVGTD
6110 6120 6130 6140 6150
LNTVKDQLNE MKEFKVEVYQ QQIEMEKLNH QGELMLKKAT DETDRDIIRE
6160 6170 6180 6190 6200
PLTELKHLWE NLGEKIAHRQ HKLEGALLAL GQFQHALEEL MSWLTHTEEL
6210 6220 6230 6240 6250
LDAQRPISGD PKVIEVELAK HHVLKNDVLA HQATVATVNK AGSELLESSA
6260 6270 6280 6290 6300
GDDASSLRSR LETMNQCWES VLQKTEEREQ QLQSTLQQAQ GFHSEIEDFL
6310 6320 6330 6340 6350
LELNRMENQL SASKPTGGLP ETAREQLDTH MELHSQLRAK EEIYNQLLDK
6360 6370 6380 6390 6400
GRLMLLSRGD SGSGSKTEQS VALLEQKWHA VSSKVEERKS KLEEALSLAT
6410 6420 6430 6440 6450
EFQNSLQEFI NWLTLAEQSL NIASPPSLIL NTVLSQIEEH KVFANEVNDH
6460 6470 6480 6490 6500
RDQIIELDQT GNQLKFLSQK QDVVLIKNLL VSVQSRWEKV VQRSIERGRS
6510 6520 6530 6540 6550
LDDARKRAKQ FHEAWKKLID WLEDAESHLD SELEISNDPD KIKLQLSKHK
6560 6570 6580 6590 6600
EFQKTLGGKQ PVYDTTIRTG RALKEKTLLA GDTQKLDNLL GEVRDKWDTV
6610 6620 6630 6640 6650
CGKSVERQHK LEEALLFSGQ FMDALQALVD WLYKVEPQLA EDQPVHGDLD
6660 6670 6680 6690 6700
LVMNLMDAHK VFQKELGKRT GTVQVLKRSG RELIEGSRDD TTWVKGQLQE
6710 6720 6730 6740 6750
LSTRWDTVCK LSVSKQSRLE QALKQAEEFR DTVHMLLEWL SEAEQTLRFR
6760 6770 6780 6790 6800
GALPDDTEAL QSLIDTHKEF MKKVEEKRVD VNTAVAMGEA ILAVCHPDCI
6810 6820 6830 6840 6850
TTIKHWITII RARFEEVLTW AKQHQQRLET ALSELVANAE LLEELLAWIQ
6860 6870 6880 6890 6900
WAETTLIQRD QEPIPQNIDR VKALITEHQS FMEEMTRKQP DVDRVTKTYK
6910 6920 6930 6940 6950
RKSVEPTHAP FMEKSRSGSR KSLNQPTPPP MPILSQSEAK NPRINQLSAR
6960 6970 6980 6990 7000
WQQVWLLALE RQRKLNDALD RLEELCPELK EFANFDFDVW RKKYMRWMNH
7010 7020 7030 7040 7050
KKSRVMDFFR RIDKDQDGKI TRQEFIDGIL ASKFPTTKLE MTAVADIFDR
7060 7070 7080 7090 7100
DGDGYIDYYE FVAALHPNKD AYRPTTDADK IEDEVTRQVA QCKCAKRFQV
7110 7120 7130 7140 7150
EQIGENKYRF FLGNQFGDSQ QLRLVRILRS TVMVRVGGGW MALDEFLVKN
7160 7170 7180 7190 7200
DPCRARGRTN IELREKFILP EGASQGMTPF RSRGRRSKPS SRAASPTRSS
7210 7220 7230 7240 7250
SSASQSNHSC TSMPSSPATP ASGTKVISSS GSKLKRPTPA FHSSRTSLAG
7260 7270 7280 7290 7300
DTSNSSSPAS TGAKANRADP KKSASRPGSR AGSRAGSRAS SRRGSDASDF
7310 7320 7330 7340 7350
DLLETQSACS DTSESSAAGG QGSSRRGLTK PSKIPTMSKK TTTASPRTPG

PKR
Length:7,353
Mass (Da):831,650
Last modified:April 8, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9D4B40945723B2C0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 18 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9QXZ0MACF1_MOUSE
Microtubule-actin cross-linking fac...
Macf1 Acf7, Aclp7, Macf
7,354Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PVY8E9PVY8_MOUSE
Microtubule-actin cross-linking fac...
Macf1
7,355Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MQA6A0A0A0MQA6_MOUSE
Microtubule-actin cross-linking fac...
Macf1
5,328Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7ACR9F7ACR9_MOUSE
Microtubule-actin cross-linking fac...
Macf1
5,333Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9QA63E9QA63_MOUSE
Microtubule-actin cross-linking fac...
Macf1
7,351Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9QNP1E9QNP1_MOUSE
Microtubule-actin cross-linking fac...
Macf1
5,478Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6Q750F6Q750_MOUSE
Microtubule-actin cross-linking fac...
Macf1
4,429Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1ARU1B1ARU1_MOUSE
Microtubule-actin cross-linking fac...
Macf1
5,895Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6YKN8F6YKN8_MOUSE
Microtubule-actin cross-linking fac...
Macf1
544Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6RCJ3F6RCJ3_MOUSE
Microtubule-actin cross-linking fac...
Macf1
452Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL606918 Genomic DNA No translation available.
AL606932 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000106224; ENSMUSP00000101831; ENSMUSG00000028649

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606918 Genomic DNA No translation available.
AL606932 Genomic DNA No translation available.

3D structure databases

SMRiB1ARU4
ModBaseiSearch...

Proteomic databases

EPDiB1ARU4
jPOSTiB1ARU4
MaxQBiB1ARU4
PeptideAtlasiB1ARU4
PRIDEiB1ARU4

Genome annotation databases

EnsembliENSMUST00000106224; ENSMUSP00000101831; ENSMUSG00000028649

Organism-specific databases

MGIiMGI:108559 Macf1

Phylogenomic databases

eggNOGiKOG0516 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00940000155824
HOGENOMiHOG000049054
PhylomeDBiB1ARU4

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Macf1 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000028649 Expressed in 318 organ(s), highest expression level in lung
ExpressionAtlasiB1ARU4 baseline and differential

Family and domain databases

CDDicd00014 CH, 2 hits
cd00051 EFh, 1 hit
Gene3Di1.10.418.10, 2 hits
3.30.920.20, 1 hit
3.90.1290.10, 6 hits
InterProiView protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR041615 Desmoplakin_SH3
IPR041573 Desmoplakin_Spectrin-like
IPR029926 Dystonin-like
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR003108 GAR_dom
IPR036534 GAR_dom_sf
IPR035915 Plakin_repeat_sf
IPR001101 Plectin_repeat
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat
PANTHERiPTHR23169:SF24 PTHR23169:SF24, 2 hits
PfamiView protein in Pfam
PF00307 CH, 2 hits
PF13499 EF-hand_7, 1 hit
PF02187 GAS2, 1 hit
PF00681 Plectin, 8 hits
PF17902 SH3_10, 1 hit
PF00435 Spectrin, 18 hits
PF18373 Spectrin_like, 1 hit
SMARTiView protein in SMART
SM00033 CH, 2 hits
SM00054 EFh, 2 hits
SM00243 GAS2, 1 hit
SM00250 PLEC, 19 hits
SM00150 SPEC, 34 hits
SUPFAMiSSF143575 SSF143575, 1 hit
SSF47473 SSF47473, 1 hit
SSF47576 SSF47576, 1 hit
SSF75399 SSF75399, 6 hits
PROSITEiView protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS00020 ACTININ_2, 1 hit
PS50021 CH, 2 hits
PS00018 EF_HAND_1, 2 hits
PS50222 EF_HAND_2, 2 hits
PS51460 GAR, 1 hit
PS50002 SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB1ARU4_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B1ARU4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: December 11, 2019
This is version 106 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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