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Protein

Schlafen family member 8

Gene

Slfn8

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Endoribonuclease that cleaves tRNAs and rRNAs (PubMed:29563550). Cleaves tRNAs 11 nucleotides from the 3'-terminus at the acceptor stem (PubMed:29563550). May be involved in immune system via regulation of inflammation (PubMed:29528433).2 Publications

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarityNote: Can also use Mn2+.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei205By similarity1
Active sitei210By similarity1
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi280ZincBy similarity1
Metal bindingi282ZincBy similarity1
Metal bindingi319ZincBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi599 – 606ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • endoribonuclease activity Source: UniProtKB
  • tRNA binding Source: GO_Central
  • zinc ion binding Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processImmunity
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Schlafen family member 8Curated (EC:3.1.-.-1 Publication)
Alternative name(s):
Schlafen-81 Publication
Short name:
mSLFN81 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Slfn81 PublicationImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2672859 Slfn8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

No visible phenotype in normal conditions. Mice are resistant in experimental autoimmune encephalomyelitis (EAE) model, a T-cell-mediated autoimmune model. The expression of pro-inflammatory mediators is severely reduced in EAE. No dysfunction of T-cells, or other leukocytes is detected.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004446071 – 910Schlafen family member 8Add BLAST910

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
B1ARD8

PeptideAtlas

More...
PeptideAtlasi
B1ARD8

PRoteomics IDEntifications database

More...
PRIDEi
B1ARD8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
B1ARD8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
B1ARD8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

In T-cells, expressed at relatively constant levels during development: expressed in immature CD3-CD4-CD8- T-cells (DN stage), in CD4+CD8+ double-positive stage (DP) and mature CD4+ or CD8+ thymocytes. Expression is slightly reduced at the DP stage.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Induced following infection.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000035208 Expressed in 132 organ(s), highest expression level in blood

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
B1ARD8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7TMF1 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000040060

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
B1ARD8

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
B1ARD8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 354N'-domain regionBy similarityAdd BLAST354

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Shows a pseudo-dimeric U-pillow-shaped architecture of the SLFN13 N'-domain that may clamp base-paired RNAs.By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Schlafen family. Subgroup III subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJEW Eukaryota
ENOG410Z5MV LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00410000025651

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000049135

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG056880

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
B1ARD8

Identification of Orthologs from Complete Genome Data

More...
OMAi
IANECHR

Database of Orthologous Groups

More...
OrthoDBi
211385at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
B1ARD8

TreeFam database of animal gene trees

More...
TreeFami
TF337168

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.950.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018647 DUF2075
IPR027417 P-loop_NTPase
IPR029684 Schlafen
IPR007421 Schlafen_AAA_dom
IPR038461 Schlafen_AAA_dom_sf
IPR029679 SLFN8/9/13

The PANTHER Classification System

More...
PANTHERi
PTHR12155 PTHR12155, 1 hit
PTHR12155:SF21 PTHR12155:SF21, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04326 AlbA_2, 1 hit
PF09848 DUF2075, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

B1ARD8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METHPSLAVK WSCPDLTIYA GEVTIGEEDR NKMDSKKRKL EKTRITEAAC
60 70 80 90 100
ALLNSGGGLI AMQMTNKSEH PVEMGQDLEK SLRELIMSPN MQAFFETKQQ
110 120 130 140 150
EDQFYIFVKS WSCRPEDGST KPRICSLGSS LYCRSITSKV AMDSREAFEF
160 170 180 190 200
LKDKKACIKY RPTDDGAPPA KIPRAMCQNS LESNPAFEIF QSKKLEYGQC
210 220 230 240 250
LLFSESTSIE FKQFSTKHVQ AYMKNIIPEY ISAFANTQGG YLFIGVDDKR
260 270 280 290 300
IILGCPKDNV DRDSLKTVAN ETISKVPVFH FCSSKDKDKV SYETRVIDVF
310 320 330 340 350
QEGNLYGYLC VIKVEPFCCA VFSEAPISWM VDKEKGVYRL NTEEWVRMMV
360 370 380 390 400
DFGPEASSKD LSKDFECQLS LCNSPPHCRP VYSKKGLQHK VDLQQRLFQV
410 420 430 440 450
SPDCLKYTPE SLWKELCSQH KRLKGLVKQQ IRSFSCGLLI LYRSWAVDLN
460 470 480 490 500
LKEKQEVICD ALLIAQNSPP ILYTILGEQD EQGQDYCNHT AFTLKQKLVN
510 520 530 540 550
TGGYTGRVCV MTKVLCLSSQ NNIETNGGSV SPINYPSSYN LANIQEMQDL
560 570 580 590 600
LQALVIVLLN FRSFLSDQLG CEILNLLTAQ QYEILSKSLR KTRELFVHGL
610 620 630 640 650
PGSGKTIIAM KIMEKIRNTF HCETDSILYI CENQPLRDFI RAKRICQAVT
660 670 680 690 700
RKTFMNYRFK TNSFQHIIVD EAQNFRTEDG NWYGKAKAIS RRVKSCPGMF
710 720 730 740 750
WIFLDYFQTS HLKESGLPDF SRQYPREELT QVVRNGDKIA EFLQKELQKI
760 770 780 790 800
RDNPPCSIPR QSLNIVHEFK WSQSVSGNIK TEQFTLEDMV IYVADKCYDF
810 820 830 840 850
LRKGYSLQDI AVLFSTDKEK KTYESMFLGE MRKRRRASEM NHAYLCDSNM
860 870 880 890 900
FDSIRRFSGL ERSIVFGINP IATEQPISHN LLLCLASRAM KHLYILYFST
910
PEGHSSTEAC
Length:910
Mass (Da):104,264
Last modified:April 8, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCEB49E7AA3F48CAE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9Q0R4E9Q0R4_MOUSE
Schlafen family member 8
Slfn8
407Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti191Q → R in BAE29925 (PubMed:16141072).Curated1
Sequence conflicti899S → P in AAP30068 (PubMed:15351786).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY261798 mRNA Translation: AAP30068.1
AL603745 Genomic DNA No translation available.
AK150875 mRNA Translation: BAE29925.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS25155.1

NCBI Reference Sequences

More...
RefSeqi
NP_853523.2, NM_181545.4
XP_006533547.1, XM_006533484.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.491599

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000038141; ENSMUSP00000040060; ENSMUSG00000035208
ENSMUST00000092838; ENSMUSP00000090513; ENSMUSG00000035208
ENSMUST00000229469; ENSMUSP00000155522; ENSMUSG00000115953
ENSMUST00000230972; ENSMUSP00000155276; ENSMUSG00000115953

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
276950

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:276950

UCSC genome browser

More...
UCSCi
uc007kod.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY261798 mRNA Translation: AAP30068.1
AL603745 Genomic DNA No translation available.
AK150875 mRNA Translation: BAE29925.1
CCDSiCCDS25155.1
RefSeqiNP_853523.2, NM_181545.4
XP_006533547.1, XM_006533484.3
UniGeneiMm.491599

3D structure databases

ProteinModelPortaliB1ARD8
SMRiB1ARD8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000040060

PTM databases

iPTMnetiB1ARD8
PhosphoSitePlusiB1ARD8

Proteomic databases

PaxDbiB1ARD8
PeptideAtlasiB1ARD8
PRIDEiB1ARD8

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
276950
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000038141; ENSMUSP00000040060; ENSMUSG00000035208
ENSMUST00000092838; ENSMUSP00000090513; ENSMUSG00000035208
ENSMUST00000229469; ENSMUSP00000155522; ENSMUSG00000115953
ENSMUST00000230972; ENSMUSP00000155276; ENSMUSG00000115953
GeneIDi276950
KEGGimmu:276950
UCSCiuc007kod.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
276950
MGIiMGI:2672859 Slfn8

Phylogenomic databases

eggNOGiENOG410IJEW Eukaryota
ENOG410Z5MV LUCA
GeneTreeiENSGT00410000025651
HOGENOMiHOG000049135
HOVERGENiHBG056880
InParanoidiB1ARD8
OMAiIANECHR
OrthoDBi211385at2759
PhylomeDBiB1ARD8
TreeFamiTF337168

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Slfn8 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000035208 Expressed in 132 organ(s), highest expression level in blood
ExpressionAtlasiB1ARD8 baseline and differential
GenevisibleiQ7TMF1 MM

Family and domain databases

Gene3Di3.30.950.30, 1 hit
InterProiView protein in InterPro
IPR018647 DUF2075
IPR027417 P-loop_NTPase
IPR029684 Schlafen
IPR007421 Schlafen_AAA_dom
IPR038461 Schlafen_AAA_dom_sf
IPR029679 SLFN8/9/13
PANTHERiPTHR12155 PTHR12155, 1 hit
PTHR12155:SF21 PTHR12155:SF21, 1 hit
PfamiView protein in Pfam
PF04326 AlbA_2, 1 hit
PF09848 DUF2075, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSLFN8_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B1ARD8
Secondary accession number(s): A0A0A0MQG0
, F6RTS1, Q3UBN9, Q7TMF1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2018
Last sequence update: April 8, 2008
Last modified: January 16, 2019
This is version 86 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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