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UniProtKB - B1AR69 (B1AR69_MOUSE)

Protein
Submitted name:

Myosin, heavy polypeptide 13, skeletal muscle

Gene

Myh13

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi179 – 186ATPPROSITE-ProRule annotation8

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

GO - Biological processi

  • cellular response to starvation Source: MGI
View the complete GO annotation on QuickGO ...

Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotationSAAS annotation, Motor protein, MyosinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin, heavy polypeptide 13, skeletal muscleImported
Gene namesi
Name:Myh13Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1339967 Myh13

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000060180 Expressed in 14 organ(s), highest expression level in skeletal muscle tissue

Interactioni

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000080584

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 82Myosin N-terminal SH3-likeInterPro annotationAdd BLAST50
Domaini86 – 782Myosin motorInterPro annotationAdd BLAST697

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni659 – 681Actin-bindingPROSITE-ProRule annotationAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili846 – 1160Sequence analysisAdd BLAST315
Coiled coili1168 – 1188Sequence analysisAdd BLAST21
Coiled coili1197 – 1238Sequence analysisAdd BLAST42
Coiled coili1246 – 1266Sequence analysisAdd BLAST21
Coiled coili1274 – 1336Sequence analysisAdd BLAST63
Coiled coili1344 – 1378Sequence analysisAdd BLAST35
Coiled coili1380 – 1442Sequence analysisAdd BLAST63
Coiled coili1457 – 1600Sequence analysisAdd BLAST144
Coiled coili1612 – 1646Sequence analysisAdd BLAST35
Coiled coili1654 – 1709Sequence analysisAdd BLAST56
Coiled coili1724 – 1807Sequence analysisAdd BLAST84
Coiled coili1809 – 1836Sequence analysisAdd BLAST28
Coiled coili1858 – 1927Sequence analysisAdd BLAST70

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0161 Eukaryota
COG5022 LUCA
GeneTreeiENSGT00930000150860
HOGENOMiHOG000173959
HOVERGENiHBG004704
KOiK10352
OMAiDDMASNI
OrthoDBiEOG091G07UM
TreeFamiTF314375

Family and domain databases

Gene3Di2.30.30.360, 1 hit
3.40.850.10, 1 hit
4.10.270.10, 1 hit
InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR027401 Myosin_IQ_contain_sf
IPR004009 Myosin_N
IPR008989 Myosin_S1_N
IPR002928 Myosin_tail
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00063 Myosin_head, 1 hit
PF02736 Myosin_N, 1 hit
PF01576 Myosin_tail_1, 1 hit
PRINTSiPR00193 MYOSINHEAVY
SMARTiView protein in SMART
SM00242 MYSc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096 IQ, 1 hit
PS51456 MYOSIN_MOTOR, 1 hit
PS51844 SH3_LIKE, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

B1AR69-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSDAEMAIF GEAAPYLRKP EKERIEAQNR PFDSKKACFA VDDKEMYVKG 
        60         70         80         90        100
MIQSRENDKV IVKTLDDREL TLNSDQVFPM NPPKFDKIED MAMMTHLHEP 
       110        120        130        140        150
AVLYNLKERY AAWMIYTYSG LFCVTVNPYK WLPVYNPEVV AAYRGKKRQE 
       160        170        180        190        200
APPHIFSISD NAYQFMLTDR DNQSILITGE SGAGKTVNTK RVIQYFATIA 
       210        220        230        240        250
VTGDKKKEQQ PGKMQGTLED QIIQANPLLE AFGNAKTVRN DNSSRFGKFI 
       260        270        280        290        300
RIHFGATGKL ASADIETYLL EKSRVTFQLS SERSYHIFYQ IMSNKKPELI 
       310        320        330        340        350
DLLLISTNPF DFPFVSQGEV TVASIDDSEE LLATDNAIDI LGFSPEEKVG 
       360        370        380        390        400
IYKLTGAVMH YGNMKFKQKQ REEQAEPDGT EVADKAGYLM GLNSAEMLKG 
       410        420        430        440        450
LCCPRVKVGN EYVTKGQNVQ QVTNSVGALA KAVYEKMFLW MVTRINQQLD 
       460        470        480        490        500
TKQPRQYFIG VLDIAGFEIF DFNSLEQLCI NFTNEKLQQF FNHHMFVLEQ 
       510        520        530        540        550
EEYKKEGIEW EFIDFGMDLA ACIELIEKPM GIFSILEEEC MFPKATDTSF 
       560        570        580        590        600
KNKLYDQHLG KSNNFQKPKP TKGKAEAHFS LVHYAGTVDY NIAGWLDKNK 
       610        620        630        640        650
DPLNETVVGL YQKSSLKLLS FLFSNYAGAE AGDSAGGKKG GKKKGSSFQT 
       660        670        680        690        700
VSAVFRENLN KLMTNLRSTH PHFVRCLIPN ETKTPGVMDH YLVMHQLRCN 
       710        720        730        740        750
GVLEGIRICR KGFPSRILYA DFKQRYRILN ASAIPEGQFI DSKNASEKLL 
       760        770        780        790        800
NSIDVDREQF RFGHTKVFFK AGLLGLLEEM RDEKLVTLMT RTQAVCRGYL 
       810        820        830        840        850
MRVEFKKMME RRESIFCIQY NVRSFMNVKH WPWMNLFFKI KPLLKSAEAE 
       860        870        880        890        900
KEMATMKEDF ERAKEDLARS EARRKELEEK MVSLLQEKND LQLQVQSETE 
       910        920        930        940        950
NLMDAEERCE GLIKSKIQLE AKVKELNERL EEEEEMNSEL VAKKRNLEDK 
       960        970        980        990       1000
CSSLKRDIDD LELTLTKVEK EKHATENKVK NLSEEMTALE ETISKLTKEK 
      1010       1020       1030       1040       1050
KSLQEAHQQT LDDLQVEEDK VNGLIKINVK LEQQTDDLEG SLEQEKKLRA 
      1060       1070       1080       1090       1100
DLERVKRKLE GDLKMSQESI MDLENDTQQL EEKLKKKEFE MSQLQTRIDD 
      1110       1120       1130       1140       1150
EQVLSLQLQK KIKELQARTE ELEEEIEAEH TVRAKIEKQR SDLARELEEI 
      1160       1170       1180       1190       1200
SERLEEASGA TSAQIEMNKK RESEFQKLRR DLEEATLQHE ATAATLRKKH 
      1210       1220       1230       1240       1250
ADTVAELGEQ IDNLQRVKQK LEKEKSELKM EIDDMASNIE TVSKSKSNME 
      1260       1270       1280       1290       1300
RMCRSVEDQF NEIKAKDDQQ TQLIHDLNMQ KARLQTQNGE LSHQVEEKES 
      1310       1320       1330       1340       1350
LVSQLTKSKQ ALTQQLEELK RQLEEETKAK NALAHALQSS RHDCDLLREQ 
      1360       1370       1380       1390       1400
YEEEQEGKAE LQRALSKANS EVAQWRTKYE TDAIQRTEEL EEAKKKLAQR 
      1410       1420       1430       1440       1450
LQEAEENTEA SNSKCASLEK TKQRLQGEVD DLMLDLERAN TACATLDKKQ 
      1460       1470       1480       1490       1500
RNFDKVLAEW KQKLDESQAE LEAAQKESRS LSTEIFKMRN AYEEVVDQLE 
      1510       1520       1530       1540       1550
TLRRENKNLQ EEISDLTEQI AETGKNLQEV EKTKKQVEQE KSDLQAALEE 
      1560       1570       1580       1590       1600
VEGSLEHEES KILRVQLELS QVKSELDRKV TEKDEEIEQI KRNSQRAVEA 
      1610       1620       1630       1640       1650
MQSVLDAEIR SRNDALRLKK KMEGDLNEME IQLSHANRQV AETQKHLRTV 
      1660       1670       1680       1690       1700
QGQLKDSQLH LDDAQRSNED LKEQLAIVER RNGLLQEELE EMKVALEQTE 
      1710       1720       1730       1740       1750
RTRRLSEQEL LDSSDRVQLL HSQNTSLINT KKKLEADLAQ CQAEVENSIQ 
      1760       1770       1780       1790       1800
ESRNAEEKAK KAITDAAMMA EELKKEQDTS AHLERMKKNL EQTVKDLQHR 
      1810       1820       1830       1840       1850
LDEAEQLALK GGKKQIQKLE ARVRELESEL DAEQKRGAEA LKGAHKYERK 
      1860       1870       1880       1890       1900
VKEMTYQAEE DRKNILRLQD LVDKLQAKVK SYKRQAEEAE EQANTQLSRC 
      1910       1920       1930 
RRVQHELEEA EERADIAESQ VNKLRAKSRD VGGQKMEE
Length:1,938
Mass (Da):223,561
Last modified:April 8, 2008 - v1
Checksum:iD98A9528EEE4697B
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QWL0M0QWL0_MOUSE
Myosin, heavy polypeptide 13, skele...
Myh13
223Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596255 Genomic DNA No translation available.
BX255958 Genomic DNA No translation available.
RefSeqiNP_001074719.1, NM_001081250.1
UniGeneiMm.461064

Genome annotation databases

EnsembliENSMUST00000081911; ENSMUSP00000080584; ENSMUSG00000060180
ENSMUST00000108684; ENSMUSP00000104324; ENSMUSG00000060180
ENSMUST00000180845; ENSMUSP00000137731; ENSMUSG00000060180
GeneIDi544791
KEGGimmu:544791
UCSCiuc007jmt.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596255 Genomic DNA No translation available.
BX255958 Genomic DNA No translation available.
RefSeqiNP_001074719.1, NM_001081250.1
UniGeneiMm.461064

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000080584

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000081911; ENSMUSP00000080584; ENSMUSG00000060180
ENSMUST00000108684; ENSMUSP00000104324; ENSMUSG00000060180
ENSMUST00000180845; ENSMUSP00000137731; ENSMUSG00000060180
GeneIDi544791
KEGGimmu:544791
UCSCiuc007jmt.1 mouse

Organism-specific databases

CTDi8735
MGIiMGI:1339967 Myh13

Phylogenomic databases

eggNOGiKOG0161 Eukaryota
COG5022 LUCA
GeneTreeiENSGT00930000150860
HOGENOMiHOG000173959
HOVERGENiHBG004704
KOiK10352
OMAiDDMASNI
OrthoDBiEOG091G07UM
TreeFamiTF314375

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000060180 Expressed in 14 organ(s), highest expression level in skeletal muscle tissue

Family and domain databases

Gene3Di2.30.30.360, 1 hit
3.40.850.10, 1 hit
4.10.270.10, 1 hit
InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR027401 Myosin_IQ_contain_sf
IPR004009 Myosin_N
IPR008989 Myosin_S1_N
IPR002928 Myosin_tail
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00063 Myosin_head, 1 hit
PF02736 Myosin_N, 1 hit
PF01576 Myosin_tail_1, 1 hit
PRINTSiPR00193 MYOSINHEAVY
SMARTiView protein in SMART
SM00242 MYSc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096 IQ, 1 hit
PS51456 MYOSIN_MOTOR, 1 hit
PS51844 SH3_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB1AR69_MOUSE
AccessioniPrimary (citable) accession number: B1AR69
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 7, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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