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Protein
Submitted name:

Dynein, axonemal, heavy chain 9

Gene

Dnah9

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Dynein, axonemal, heavy chain 9Imported
Gene namesi
Name:Dnah9Imported
Synonyms:Dnahc9Imported
ORF Names:RP23-215H18.2-001Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1289279 Dnah9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000056752 Expressed in 59 organ(s), highest expression level in embryo

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiB1AR51, 1 interactor
B1AR51, 1 interactor
STRINGi10090.ENSMUSP00000079494

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini213 – 787DHC_N1InterPro annotationAdd BLAST575
Domaini1290 – 1694DHC_N2InterPro annotationAdd BLAST405
Domaini1830 – 2060AAA_6InterPro annotationAdd BLAST231
Domaini2145 – 2279AAA_5InterPro annotationAdd BLAST135
Domaini2786 – 3053AAA_8InterPro annotationAdd BLAST268
Domaini3065 – 3408MTInterPro annotationAdd BLAST344
Domaini3435 – 3652AAA_9InterPro annotationAdd BLAST218
Domaini3789 – 4482Dynein_heavyInterPro annotationAdd BLAST694

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili639 – 659Sequence analysisAdd BLAST21
Coiled coili788 – 815Sequence analysisAdd BLAST28
Coiled coili1460 – 1480Sequence analysisAdd BLAST21
Coiled coili3050 – 3070Sequence analysisAdd BLAST21
Coiled coili3074 – 3101Sequence analysisAdd BLAST28
Coiled coili3123 – 3143Sequence analysisAdd BLAST21
Coiled coili3287 – 3335Sequence analysisAdd BLAST49
Coiled coili3642 – 3662Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3595 Eukaryota
COG5245 LUCA
GeneTreeiENSGT00910000144015
HOGENOMiHOG000237309
HOVERGENiHBG107831
KOiK10408
OMAiHYQADME
OrthoDBiEOG091G00Z2
TreeFamiTF316836

Family and domain databases

InterProiView protein in InterPro
IPR035699 AAA_6
IPR011704 ATPase_dyneun-rel_AAA
IPR035706 DHC_D5
IPR026983 DHC_fam
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_dom
IPR013594 Dynein_heavy_dom-1
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PfamiView protein in Pfam
PF07728 AAA_5, 1 hit
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF08385 DHC_N1, 1 hit
PF08393 DHC_N2, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SUPFAMiSSF52540 SSF52540, 4 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

B1AR51-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPGAKEQAAL AESGDEEPGD PRLRLLGTFV ARSLRPAAGT WERCAGTAEA
60 70 80 90 100
GRLLQAFLDH NAASDPRPLL VVQSGPGGLV VTPGLDAGPE PSRARAKGLF
110 120 130 140 150
FLRTKSEPPG NHSLRGTVLC GDLPAVPLEH LAPLLSEVII PVLANEKNHL
160 170 180 190 200
EWPHMVCQDI RHHAHTLKSD LLVIFEHMKG RTLLPLPVGS EKLEFVDGHS
210 220 230 240 250
EPVSDAIDKS TLYAVESAVI KWSHQVQVVL KRESSQALIQ GQNPTPKVEL
260 270 280 290 300
EFWKSRCEDL EHIYNQLMTI KVKGMAELLD KLQSSYLPAF KAMFRDVEAA
310 320 330 340 350
LTEAQDIHVH LLPLQQHLDI LENVEFPKVK GRLRPLLHVV CLIWATCKWY
360 370 380 390 400
RSPGRLTVLL QEICNLLIQQ ASNYLSPEDL LRSEVEESQK KLQVVSDTLS
410 420 430 440 450
FFKQAFQDRR EHLHTYFKED SEVRVWDFQA SLVFVRLDGF LGRVHMVEDL
460 470 480 490 500
LKTALDLNNL EKLEFSGLRG NSLSQKVQRM HEEFEEMYKV FLDCSYDCLD
510 520 530 540 550
PKGTEFENDV CEFNKRVEDL DRRLGTILIQ AFDDAPDVEH AFKLLDITGT
560 570 580 590 600
LIKRPLVAQD VSQKYLALIR MFSTELDAVR VIYSQHIQKE AEHGFSPVHK
610 620 630 640 650
NMPTMAGGIC WAQELRQRVK GPFGNFKNIP HLYLQSAEGK RMIQKYEDLL
660 670 680 690 700
SLLEEYERRL YEDWCQTVSE KSQYNLSLPL LHRDPNTKQL SVNFNPQLIS
710 720 730 740 750
VLKEMNYLQP SEVKTIPETA AAMFSSREFY RQLVANLELM ANWYNKVIKI
760 770 780 790 800
LLEVEFPLVE EELQNIDLRL RAAEETLSWK TEGIWDYAMQ ITNSIHDLEQ
810 820 830 840 850
RIQKTKDNVE EIQNIMKTWV SPIFKRKDGK KEWPLSLDDQ QDHMEKYYSL
860 870 880 890 900
IQESGLKIHA LVQENLVLFA ADPASSIWKS YVNYIDSMLL DGFFLAIECS
910 920 930 940 950
LKYLLENTEC KPGLTPVFEA QLNLVTPELV FHPSLDSGVK GGLYDIVQSL
960 970 980 990 1000
VTRIFAMPSL VPRLSPHSGS PHYQGDLEDM ADLAGLRSVL MERVQNMMTL
1010 1020 1030 1040 1050
CCGYRNTLSQ YSYLYVEDRK EILGQFLLYG HVLTPEEIEA HAEDGIPENP
1060 1070 1080 1090 1100
PLLHHFKDQI DSYEKLYEEV VSLEPTKVFD GWMRVDVRPF KASLLNTIKK
1110 1120 1130 1140 1150
WSLMFKQHLV DFVTNSLSDL DSFIRSTESG LLKRVEKGDF QGLVEIMGHL
1160 1170 1180 1190 1200
VTLKERQSST DDMFEPLKQT IELLKSYEQE LPETVFKQLE ELPEKWKNMK
1210 1220 1230 1240 1250
KMAITVRQQV APLQANEVAL LRQRCSAFDD EQQQFQERFR KEAPFRFDSI
1260 1270 1280 1290 1300
NPHQMLDAWH VEIQHMESTM ATISKSADLF EVNVPDYKQL RQCRKEACQL
1310 1320 1330 1340 1350
KELWDTIGMV TSSIRAWEAT SWRNISVEAM DSECKQFARH IRNLDKEFRS
1360 1370 1380 1390 1400
WDAFTGLEST VLNTLTSLRA VAELQNPAIR DRHWRQLMQA TGVNFTMNQD
1410 1420 1430 1440 1450
TTLAHLLQLQ LHHFEDEVRG IVDRAVKEMS MEKTLKELQT TWASMEFQYE
1460 1470 1480 1490 1500
SHARTRVPLL QSDEDLIEVL EDNQVQLQNL MMSKYVAFFL EEVSSWQKKL
1510 1520 1530 1540 1550
STADSVISIW FEVQRTWSHL ESIFIGSEDI RAQLPQDSKR FEGIDSDFRE
1560 1570 1580 1590 1600
LAYDAQKTPN VVEATNKSGL YEKLEDIQSR LCLCEKALAE YLDTKRLSFP
1610 1620 1630 1640 1650
RFYFLSSSDL LDILSNGTAP QQVQRHLSKL FDNMAKMQFQ LDASQNPTKT
1660 1670 1680 1690 1700
SLGMYSKEEE YVAFSEACDC SGQVEIWLNR VLRHMKATVR HEMTEGVTAY
1710 1720 1730 1740 1750
EEKPRDQWLF DYPAQVALTC TQIWWTTEVG IAFARLEEGY ESAMKDYYKK
1760 1770 1780 1790 1800
QVAQLKTLIT MLIGPLSKGD RQKIMTICTI DVHARDVVAK MIAQKVDNAQ
1810 1820 1830 1840 1850
AFLWLSQLRH RWDDEAKHCF ANICDAQFLY SYEYLGNTPR LVITPLTDRC
1860 1870 1880 1890 1900
YITLTQSLHL TMSGAPAGPA GTGKTETTKD LGRALGIMVY VFNCSEQMDY
1910 1920 1930 1940 1950
KSCGNIYKGL AQTGAWGCFD EFNRISVEVL SVVAVQVKSI QDAIRDKKQR
1960 1970 1980 1990 2000
FSFLGEEISL DPSVGIFITM NPGYAGRTEL PENLKALFRP CAMVVPDFEL
2010 2020 2030 2040 2050
ISEIMLVAEG FIEARLLARK FITLYRLCKE LLSKQDHYDW GLRAIKSVLV
2060 2070 2080 2090 2100
VAGSLKRGDP DRPEDQVLMR SLRDFNIPKI VTDDMPVFMG LIGDLFPALD
2110 2120 2130 2140 2150
VPRKRDLDFE AVVRKAIVDL KLQAEDNFVL KVVQLEELLA VRHSVFVVGG
2160 2170 2180 2190 2200
AGTGKSQVLR SLHKTYQIMR RRPVWTDLNP KAVTNDELFG IINPATREWK
2210 2220 2230 2240 2250
DGLFSSIMRE LAIISHDGPK WILLDGDIDP MWIESLNTVM DDNKVLTLAS
2260 2270 2280 2290 2300
NERIPLNPTM RLLFEISHLR TATPATVSRA GILYINPADL GWNPPVSSWI
2310 2320 2330 2340 2350
DQREVQTERA NLTILFDKYL PTCLDTLRTR FKKIIPVPEQ SMIQMLCYLL
2360 2370 2380 2390 2400
ECLLTKEDIP ADCPKEIYEL YFVFAAIWAF GSAVIQDQLV DYRAEFSKWW
2410 2420 2430 2440 2450
LTEFKTVKFP SQGTVFDYYI DPETKKFEPW AKLIPQFEFD PEMPLQACLV
2460 2470 2480 2490 2500
HTSETIRVCY FMERLMQWRR PVMLVGPAGS GKSVLVGAKL SSLNPEEYMV
2510 2520 2530 2540 2550
KNVPFNYYTT SAMLQAVLEK PLEKKAGRNY GPPGNRKLIY FIDDMNMPEV
2560 2570 2580 2590 2600
DAYGTVQPHT VIRQHLDYGH WYDRNKLSLK EIMNVQYISC MNPTAGSFTI
2610 2620 2630 2640 2650
NPRLQRHFSV FALCFPGADA LSSIYSTILT HHLKFGNFPT TLQKSIPPLI
2660 2670 2680 2690 2700
NLAVTFHQKI ATTFLPTAIK FHYIFNLRDF ANIFQGILFS SVECVKSTQD
2710 2720 2730 2740 2750
LVKLYLHESS RVYRDKMVEE KDFNLFDKIQ TEFLKKNFDD SEEVLKQTQN
2760 2770 2780 2790 2800
LNMYCHFANG IGEPKYMPVQ SWDLLNQTLV EALESHNEVN AVMDLVLFED
2810 2820 2830 2840 2850
AIRHICHINR ILESPRGNAL LVGVGGSGKQ SLTKLAAFIS SMDVFQITLR
2860 2870 2880 2890 2900
KGYQIPDFKV DLASLCLKAG VKNLSTVFLM TDAHVADERF LVLINDLLAS
2910 2920 2930 2940 2950
GEIPDLYSDE EEENIINNVR NEVKSQGLMD SRENCWKFFI ERVQRQLKVT
2960 2970 2980 2990 3000
LCFSPVGNKL RIRSRKFPAI VNCTAINWFH EWPQEALESV SLRFLQNTKN
3010 3020 3030 3040 3050
IEPAVKQSIS KFMAFVHISV NKTSQSYLTN EQRYNYTTPK SFLEFIRLYQ
3060 3070 3080 3090 3100
SLLERNGKEL QAKVERLENG LLKLHSTSAQ VDDLKAKLAT QEVELRHKNE
3110 3120 3130 3140 3150
DTDKLIQVVG VETSKVSREK AIADEEEQKV ALIMLEVQQK QKDCEEDLAK
3160 3170 3180 3190 3200
AEPALTAAQA ALNTLNKTNL TELKSFGSPP LAVSNVSAAV MVLMAPGGKV
3210 3220 3230 3240 3250
PKDRSWKAAK ITMAKVDSFL DSLIHFDKEN IHENCLKAIR PYLQDPAFNP
3260 3270 3280 3290 3300
EFVATKSYAA AGLCSWVINI VRFYEVFCDV EPKRQALNKA TSDLTTAQEK
3310 3320 3330 3340 3350
LAAIKAKITH LNENLAKLTT KFEKATAEKL KCQQEAELTA GTISLANRLV
3360 3370 3380 3390 3400
GGLASENIRW AEAVQNFRQQ ERTLCGDILL TTAFISYLGF FTKKYRKSLM
3410 3420 3430 3440 3450
DGTWRPYLSQ LKVPIPTTPT LDPLRMLTDD AEVAAWQNEG LPADRMSMEN
3460 3470 3480 3490 3500
ATILINCERW PLMVDPQLQG IKWIKNKYGE ELRVTQIGQK GCLQTIERAL
3510 3520 3530 3540 3550
EAGDVVLIEN LEESIDPVLG PLLGREVIKK GRFIKIGDKE CEFNPKFRLI
3560 3570 3580 3590 3600
LHTKLANPHY QPELQAQATL INFTVTRDGL EDQLLAAVVS MERPDLEQLK
3610 3620 3630 3640 3650
SDLTKQQNGF KITLKTLEDN LLSRLSSASG NFLGETALVE NLEVTKQTAA
3660 3670 3680 3690 3700
DVEEKVQEAK LTEVKINEAR EHYRPAAARA SLLYFIMNDL SKIHPMYQFS
3710 3720 3730 3740 3750
LKAFSIVFQK AVEKAAPSES VTERVTNLID SITFSVYQYT TRGLFECDKL
3760 3770 3780 3790 3800
TYLAQLTFQI LLVNQEVNAA ELDFLLRAPV QTGTPSPMEF LSHQAWGGIK
3810 3820 3830 3840 3850
ALSSMEEFCN LDRDIEGSAK SWKKFVESEC PEKEKFPQEW KNKTALQRLC
3860 3870 3880 3890 3900
MMRAMRPDRM TYAMRDFVEE KLGSKYVMGR ALDFVTSFEE SGPATPMFFI
3910 3920 3930 3940 3950
LSPGVDPLKD VENQGKKLGY TFNNRNFHNV SLGQGQEVVA EAALDLAAKK
3960 3970 3980 3990 4000
GHWVILQNIH LVAKWLSTLE KKLEELSEES HPDFRVFISA EPAPSPEGHI
4010 4020 4030 4040 4050
IPQGILENSI KITNEPPTGM HANLHKALDN FTQDTLEMCS RETEFKTILF
4060 4070 4080 4090 4100
ALCYFHAVVA ERRKFGPQGW NRSYPFNTGD LTISVNVLYN FLEANTKVPY
4110 4120 4130 4140 4150
DDLRYLFGEI MYGGHITDDW DRRLCRTYLE EFIRPEMLEG ELSLAPGFPL
4160 4170 4180 4190 4200
PGNMDYSGYH QYIDAELPPE SPYLYGLHPN AEIGFLTQTS EKLFRTVLEM
4210 4220 4230 4240 4250
QPRDSQAGDG AGITREEKVK TFLEEILDRM TDEFNIAELM AKVEERTPYI
4260 4270 4280 4290 4300
VVALQECERM NILTREIQRS LRELHLGLQG ELTMTSEMEN LQNALYLDVV
4310 4320 4330 4340 4350
PESWARRAYP STAGLAAWFL DLLNRIKELE SWTGDFLMPS TVWLTGFFNP
4360 4370 4380 4390 4400
QSFLTAIMQS MARKNEWPLD QMALQCDVTK KNREEFRSPP REGAYIYGLF
4410 4420 4430 4440 4450
MEGACWDTQT GIIAEAKLKD LTPPMPVMFL KAIPADKQDC RSVYACPVYK
4460 4470 4480
TCQRGPTYVW TFNLKTKENP SKWVLAGVAL LLQI
Length:4,484
Mass (Da):512,361
Last modified:April 8, 2008 - v1
Checksum:i1DC3F25611E9594E
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F7DC70F7DC70_MOUSE
Dynein, axonemal, heavy chain 9
Dnah9 Dnahc9
1,958Annotation score:
B7FAT5B7FAT5_MOUSE
Dynein, axonemal, heavy chain 9
Dnah9 Dnahc9, RP23-215H18.2-002
279Annotation score:
Q5SX07Q5SX07_MOUSE
Dynein, axonemal, heavy chain 9
Dnah9 Dnahc9
457Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596025, AL596187 Genomic DNA Translation: CAI24582.1
RefSeqiNP_001093103.1, NM_001099633.1
UniGeneiMm.264210
Mm.459279

Genome annotation databases

EnsembliENSMUST00000080665; ENSMUSP00000079494; ENSMUSG00000056752
GeneIDi237806
KEGGimmu:237806
UCSCiuc007jlg.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596025, AL596187 Genomic DNA Translation: CAI24582.1
RefSeqiNP_001093103.1, NM_001099633.1
UniGeneiMm.264210
Mm.459279

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB1AR51, 1 interactor
B1AR51, 1 interactor
STRINGi10090.ENSMUSP00000079494

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000080665; ENSMUSP00000079494; ENSMUSG00000056752
GeneIDi237806
KEGGimmu:237806
UCSCiuc007jlg.1 mouse

Organism-specific databases

CTDi1770
MGIiMGI:1289279 Dnah9

Phylogenomic databases

eggNOGiKOG3595 Eukaryota
COG5245 LUCA
GeneTreeiENSGT00910000144015
HOGENOMiHOG000237309
HOVERGENiHBG107831
KOiK10408
OMAiHYQADME
OrthoDBiEOG091G00Z2
TreeFamiTF316836

Miscellaneous databases

ChiTaRSiDnah9 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000056752 Expressed in 59 organ(s), highest expression level in embryo

Family and domain databases

InterProiView protein in InterPro
IPR035699 AAA_6
IPR011704 ATPase_dyneun-rel_AAA
IPR035706 DHC_D5
IPR026983 DHC_fam
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_dom
IPR013594 Dynein_heavy_dom-1
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PfamiView protein in Pfam
PF07728 AAA_5, 1 hit
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF08385 DHC_N1, 1 hit
PF08393 DHC_N2, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SUPFAMiSSF52540 SSF52540, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiB1AR51_MOUSE
AccessioniPrimary (citable) accession number: B1AR51
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 7, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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