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Protein
Submitted name:

Kinetochore protein Nuf2

Gene

NUF2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Kinetochore protein Nuf2Imported
Gene namesi
Name:NUF2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000143228.12
HGNCiHGNC:14621 NUF2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143228

PTM / Processingi

Proteomic databases

MaxQBiB1AQT4
PeptideAtlasiB1AQT4
PRIDEiB1AQT4

Expressioni

Gene expression databases

BgeeiENSG00000143228 Expressed in 126 organ(s), highest expression level in testis
ExpressionAtlasiB1AQT4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB1AQT4
SMRiB1AQT4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili149 – 172Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4438 Eukaryota
ENOG410ZI4C LUCA
GeneTreeiENSGT00390000004199
HOGENOMiHOG000290701

Family and domain databases

Gene3Di1.10.418.60, 1 hit
InterProiView protein in InterPro
IPR005549 Kinetochore_Nuf2
IPR038275 Nuf2_N_sf
PfamiView protein in Pfam
PF03800 Nuf2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

B1AQT4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METLSFPRYN VAEIVIHIRN KILTGADGKN LTKNDLYPNP KPEVLHMIYM
60 70 80 90 100
RALQIVYGIR LEHFYMMPVN SEVMYPHLME GFLPFSNLVT HLDSFLPICR
110 120 130 140 150
VNDFETADIL CPKAKRTSRF LSGIINFIHF REACRETYME FLWQYKSSAD
160 170 180 190 200
KMQQLNAAHQ EALMKLERLD SVPVEEQEEF KQLSDGIQEL QQSLNQDFHQ

KT
Length:202
Mass (Da):23,732
Last modified:April 8, 2008 - v1
Checksum:i94C758560C86A170
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9BZD4NUF2_HUMAN
Kinetochore protein Nuf2
NUF2 CDCA1, NUF2R
464Annotation score:
E9PQC4E9PQC4_HUMAN
Kinetochore protein Nuf2
NUF2
417Annotation score:
E9PKH1E9PKH1_HUMAN
Kinetochore protein Nuf2
NUF2
124Annotation score:
B1AQT3B1AQT3_HUMAN
Kinetochore protein Nuf2
NUF2
145Annotation score:
E9PP32E9PP32_HUMAN
Kinetochore protein Nuf2
NUF2
221Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei202Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL592435 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000442820; ENSP00000392652; ENSG00000143228
UCSCiuc057mwp.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL592435 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliB1AQT4
SMRiB1AQT4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB1AQT4
PeptideAtlasiB1AQT4
PRIDEiB1AQT4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000442820; ENSP00000392652; ENSG00000143228
UCSCiuc057mwp.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000143228.12
HGNCiHGNC:14621 NUF2
OpenTargetsiENSG00000143228
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4438 Eukaryota
ENOG410ZI4C LUCA
GeneTreeiENSGT00390000004199
HOGENOMiHOG000290701

Gene expression databases

BgeeiENSG00000143228 Expressed in 126 organ(s), highest expression level in testis
ExpressionAtlasiB1AQT4 baseline and differential

Family and domain databases

Gene3Di1.10.418.60, 1 hit
InterProiView protein in InterPro
IPR005549 Kinetochore_Nuf2
IPR038275 Nuf2_N_sf
PfamiView protein in Pfam
PF03800 Nuf2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB1AQT4_HUMAN
AccessioniPrimary (citable) accession number: B1AQT4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 12, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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