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Protein
Submitted name:

Death effector domain containing, isoform CRA_b

Gene

DEDD

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Death effector domain containing, isoform CRA_bImported
Submitted name:
Death effector domain-containing proteinImported
Gene namesi
Name:DEDDImported
ORF Names:hCG_20845Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000158796.16
HGNCiHGNC:2755 DEDD

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000158796

PTM / Processingi

Proteomic databases

MaxQBiB1AQP5
PRIDEiB1AQP5

Expressioni

Gene expression databases

BgeeiENSG00000158796 Expressed in 236 organ(s), highest expression level in vagina
ExpressionAtlasiB1AQP5 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 103DEDInterPro annotationAdd BLAST79

Phylogenomic databases

GeneTreeiENSGT00390000008714
HOGENOMiHOG000049120
HOVERGENiHBG007220
OMAiCPDPVDK
OrthoDBiEOG091G07VX

Family and domain databases

InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR001875 DED_dom
IPR038856 DEDD/DEDD2
PANTHERiPTHR15205 PTHR15205, 1 hit
PfamiView protein in Pfam
PF01335 DED, 1 hit
SMARTiView protein in SMART
SM00031 DED, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50168 DED, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

B1AQP5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGLKRRASQ VWPEEHGEQE HGLYSLHRMF DIVGTHLTHR DVRVLSFLFV
60 70 80 90 100
DVIDDHERGL IRNGRDFLLA LERQGRCDES NFRQVLQLLR IITRHDLLPY
110 120 130 140 150
VTLKRRRAVC PDLVDKYLEE TSIRYVTPRA LSDPEPRPPQ PSKTVPPHYP
160 170 180 190 200
VVCCPTSGPQ MCSKRPARGR ATLGSQRKRR KSVTPDPKEK QTCGEEVQGF
210 220 230 240 250
QRWSRLEGEY KELLGHWAVY AIQYIRLRVR AEYCQHETAL QGNVFSNKQD
260 270 280 290 300
PLERQFERFN QANTILKSRD LGSIICDIKF SELTYLDAFW RDYINGSLLE
310 320 330 340
ALKGVFITDS LKQAVGHEAI KLLVNVDEED YELGRQKLLR NLMLQALP
Length:348
Mass (Da):40,404
Last modified:April 8, 2008 - v1
Checksum:iB78A39BB706E9260
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O75618DEDD_HUMAN
Death effector domain-containing pr...
DEDD DEDPRO1, DEFT, KE05
318Annotation score:
V9GY27V9GY27_HUMAN
Death effector domain-containing pr...
DEDD
287Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591806 Genomic DNA No translation available.
CH471121 Genomic DNA Translation: EAW52649.1
RefSeqiNP_001317694.1, NM_001330765.1
XP_005245655.1, XM_005245598.4
XP_005245656.1, XM_005245599.2
XP_005245657.1, XM_005245600.2
UniGeneiHs.744092

Genome annotation databases

EnsembliENST00000368005; ENSP00000356984; ENSG00000158796
GeneIDi9191
UCSCiuc009wty.5 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591806 Genomic DNA No translation available.
CH471121 Genomic DNA Translation: EAW52649.1
RefSeqiNP_001317694.1, NM_001330765.1
XP_005245655.1, XM_005245598.4
XP_005245656.1, XM_005245599.2
XP_005245657.1, XM_005245600.2
UniGeneiHs.744092

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB1AQP5
PRIDEiB1AQP5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000368005; ENSP00000356984; ENSG00000158796
GeneIDi9191
UCSCiuc009wty.5 human

Organism-specific databases

CTDi9191
EuPathDBiHostDB:ENSG00000158796.16
HGNCiHGNC:2755 DEDD
OpenTargetsiENSG00000158796
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000008714
HOGENOMiHOG000049120
HOVERGENiHBG007220
OMAiCPDPVDK
OrthoDBiEOG091G07VX

Miscellaneous databases

ChiTaRSiDEDD human
GenomeRNAii9191

Gene expression databases

BgeeiENSG00000158796 Expressed in 236 organ(s), highest expression level in vagina
ExpressionAtlasiB1AQP5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR001875 DED_dom
IPR038856 DEDD/DEDD2
PANTHERiPTHR15205 PTHR15205, 1 hit
PfamiView protein in Pfam
PF01335 DED, 1 hit
SMARTiView protein in SMART
SM00031 DED, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50168 DED, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB1AQP5_HUMAN
AccessioniPrimary (citable) accession number: B1AQP5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 10, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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