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Protein
Submitted name:

Rho guanine nucleotide exchange factor 7

Gene

ARHGEF7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Rho guanine nucleotide exchange factor 7Imported
Gene namesi
Name:ARHGEF7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000102606.17
HGNCiHGNC:15607 ARHGEF7

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000102606

PTM / Processingi

Proteomic databases

MaxQBiB1ANY6
PeptideAtlasiB1ANY6
PRIDEiB1ANY6

Expressioni

Gene expression databases

BgeeiENSG00000102606 Expressed in 224 organ(s), highest expression level in corpus callosum
ExpressionAtlasiB1ANY6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB1ANY6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 65SH3InterPro annotationAdd BLAST60

Keywords - Domaini

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2070 Eukaryota
ENOG410XNNP LUCA
GeneTreeiENSGT00930000150955

Family and domain databases

CDDicd12061 SH3_betaPIX, 1 hit
InterProiView protein in InterPro
IPR035789 BetaPIX_SH3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF07653 SH3_2, 1 hit
PRINTSiPR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50002 SH3, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

B1ANY6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDNSNNQLV VRAKFNFQQT NEDELSFSKG DVIHVTRVEE GGWWEGTLNG
60
RTGWFPSNYV REVKAS
Length:66
Mass (Da):7,578
Last modified:April 8, 2008 - v1
Checksum:iA3CF21107FD0CB86
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q14155ARHG7_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7 COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
803Annotation score:
B1ALK7B1ALK7_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
705Annotation score:
E9PDQ5E9PDQ5_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
547Annotation score:
E7EUY6E7EUY6_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
447Annotation score:
A0A2R8YG42A0A2R8YG42_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
862Annotation score:
E7ENL8E7ENL8_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
143Annotation score:
E7EU80E7EU80_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
151Annotation score:
C9JDI6C9JDI6_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
61Annotation score:
F6SJA5F6SJA5_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
130Annotation score:
C9JAD7C9JAD7_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
39Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei66Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139086 Genomic DNA No translation available.
AL353704 Genomic DNA No translation available.
AL390754 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000449979; ENSP00000406732; ENSG00000102606
UCSCiuc058yic.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139086 Genomic DNA No translation available.
AL353704 Genomic DNA No translation available.
AL390754 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliB1ANY6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB1ANY6
PeptideAtlasiB1ANY6
PRIDEiB1ANY6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000449979; ENSP00000406732; ENSG00000102606
UCSCiuc058yic.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000102606.17
HGNCiHGNC:15607 ARHGEF7
OpenTargetsiENSG00000102606
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2070 Eukaryota
ENOG410XNNP LUCA
GeneTreeiENSGT00930000150955

Miscellaneous databases

ChiTaRSiARHGEF7 human

Gene expression databases

BgeeiENSG00000102606 Expressed in 224 organ(s), highest expression level in corpus callosum
ExpressionAtlasiB1ANY6 baseline and differential

Family and domain databases

CDDicd12061 SH3_betaPIX, 1 hit
InterProiView protein in InterPro
IPR035789 BetaPIX_SH3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF07653 SH3_2, 1 hit
PRINTSiPR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50002 SH3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB1ANY6_HUMAN
AccessioniPrimary (citable) accession number: B1ANY6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 7, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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