UniProtKB - B1AM21 (B1AM21_HUMAN)
Protein
Submitted name:
Guanine nucleotide-binding protein G(q) subunit alpha
Gene
GNAQ
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- G-protein beta/gamma-subunit complex binding Source: InterPro
- GTPase activity Source: InterPro
- guanyl nucleotide binding Source: InterPro
GO - Biological processi
- G protein-coupled receptor signaling pathway Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Guanine nucleotide-binding protein G(q) subunit alphaImported |
Gene namesi | Name:GNAQImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:4390, GNAQ |
VEuPathDBi | HostDB:ENSG00000156052.10 |
PTM / Processingi
Proteomic databases
MaxQBi | B1AM21 |
PeptideAtlasi | B1AM21 |
PRIDEi | B1AM21 |
ProteomicsDBi | 3180 |
PTM databases
SwissPalmi | B1AM21 |
Expressioni
Gene expression databases
Bgeei | ENSG00000156052, Expressed in thoracic mammary gland and 255 other tissues |
ExpressionAtlasi | B1AM21, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 22 | DisorderedSequence analysisAdd BLAST | 22 |
Phylogenomic databases
GeneTreei | ENSGT00940000161347 |
HOGENOMi | CLU_014184_6_1_1 |
Family and domain databases
CDDi | cd00066, G-alpha, 1 hit |
Gene3Di | 1.10.400.10, 1 hit |
InterProi | View protein in InterPro IPR001019, Gprotein_alpha_su IPR011025, GproteinA_insert |
PANTHERi | PTHR10218, PTHR10218, 1 hit |
Pfami | View protein in Pfam PF00503, G-alpha, 1 hit |
PRINTSi | PR00318, GPROTEINA |
SMARTi | View protein in SMART SM00275, G_alpha, 1 hit |
SUPFAMi | SSF47895, SSF47895, 1 hit |
PROSITEi | View protein in PROSITE PS51882, G_ALPHA, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
B1AM21-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGERWADSQL DSRSTHGTGE SGKSTFIKQM RIIHGSGYSD EDKRGFTKLV
60 70 80 90 100
YQNIFTAMQA MIRAMDTLKI PYKYEHNKAH AQLVREVDVE KVSAFENPYV
110 120 130 140 150
DAIKSLWNDP GIQECYDRRR EYQLSDSTKY YLNDLDRVAD PAYLPTQQDV
160 170
LRVRVPTTGI IEYPFDLQSV
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketP50148 | GNAQ_HUMAN | Guanine nucleotide-binding protein ... | GNAQ GAQ | 359 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 170 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL160268 Genomic DNA No translation available. AL160278 Genomic DNA No translation available. AL355535 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000411677; ENSP00000391501; ENSG00000156052 |
UCSCi | uc064tvp.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL160268 Genomic DNA No translation available. AL160278 Genomic DNA No translation available. AL355535 Genomic DNA No translation available. |
3D structure databases
SMRi | B1AM21 |
ModBasei | Search... |
PTM databases
SwissPalmi | B1AM21 |
Proteomic databases
MaxQBi | B1AM21 |
PeptideAtlasi | B1AM21 |
PRIDEi | B1AM21 |
ProteomicsDBi | 3180 |
Protocols and materials databases
Antibodypediai | 4101, 278 antibodies |
Genome annotation databases
Ensembli | ENST00000411677; ENSP00000391501; ENSG00000156052 |
UCSCi | uc064tvp.1, human |
Organism-specific databases
HGNCi | HGNC:4390, GNAQ |
OpenTargetsi | ENSG00000156052 |
VEuPathDBi | HostDB:ENSG00000156052.10 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000161347 |
HOGENOMi | CLU_014184_6_1_1 |
Miscellaneous databases
ChiTaRSi | GNAQ, human |
Gene expression databases
Bgeei | ENSG00000156052, Expressed in thoracic mammary gland and 255 other tissues |
ExpressionAtlasi | B1AM21, baseline and differential |
Family and domain databases
CDDi | cd00066, G-alpha, 1 hit |
Gene3Di | 1.10.400.10, 1 hit |
InterProi | View protein in InterPro IPR001019, Gprotein_alpha_su IPR011025, GproteinA_insert |
PANTHERi | PTHR10218, PTHR10218, 1 hit |
Pfami | View protein in Pfam PF00503, G-alpha, 1 hit |
PRINTSi | PR00318, GPROTEINA |
SMARTi | View protein in SMART SM00275, G_alpha, 1 hit |
SUPFAMi | SSF47895, SSF47895, 1 hit |
PROSITEi | View protein in PROSITE PS51882, G_ALPHA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B1AM21_HUMAN | |
Accessioni | B1AM21Primary (citable) accession number: B1AM21 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 8, 2008 |
Last sequence update: | April 8, 2008 | |
Last modified: | April 7, 2021 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |