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Protein
Submitted name:

AP-4 complex subunit beta-1

Gene

AP4B1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processProtein transportSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
AP-4 complex subunit beta-1Imported
Gene namesi
Name:AP4B1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000134262.12
HGNCiHGNC:572 AP4B1

Subcellular locationi

Keywords - Cellular componenti

MembraneSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000134262

PTM / Processingi

Proteomic databases

MaxQBiB1ALD2
PeptideAtlasiB1ALD2
PRIDEiB1ALD2

Expressioni

Gene expression databases

BgeeiENSG00000134262 Expressed in 201 organ(s), highest expression level in right hemisphere of cerebellum
ExpressionAtlasiB1ALD2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB1ALD2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 259Adaptin_NInterPro annotationAdd BLAST249

Phylogenomic databases

eggNOGiKOG1061 Eukaryota
COG5096 LUCA
GeneTreeiENSGT00530000063138
HOGENOMiHOG000294128
HOVERGENiHBG091836

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR026739 AP_beta
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
PANTHERiPTHR11134 PTHR11134, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

B1ALD2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPYLGSEDVV KELKKALCNP HIQADRLRYR NVIQRVIRYM TQGLDMSGVF
60 70 80 90 100
MEMVKASATV DIVQKKLVYL YMCTYAPLKP DLALLAINTL CKDCSDPNPM
110 120 130 140 150
VRGLALRSMC SLRMPGVQEY IQQPILNGLR DKASYVRRVA VLGCAKMHNL
160 170 180 190 200
HGDSEVDGAL VNELYSLLRD QDPIVVVNCL RSLEEILKQE GGVVINKPIA
210 220 230 240 250
HHLLNRMSKL DQWGQAEVLN FLLRYQPRSE EELFDILNLL DSFLKSSSPG
260
VVMGATKLFL IL
Length:262
Mass (Da):29,593
Last modified:April 8, 2008 - v1
Checksum:iCCA9A1C9040F5D2B
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9Y6B7AP4B1_HUMAN
AP-4 complex subunit beta-1
AP4B1
739Annotation score:
B1ALD0B1ALD0_HUMAN
AP complex subunit beta
AP4B1
571Annotation score:
B1ALD1B1ALD1_HUMAN
AP-4 complex subunit beta-1
AP4B1
296Annotation score:
B1ALD3B1ALD3_HUMAN
AP-4 complex subunit beta-1
AP4B1
175Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei262Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137856 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000369571; ENSP00000358584; ENSG00000134262
UCSCiuc057jot.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137856 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliB1ALD2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB1ALD2
PeptideAtlasiB1ALD2
PRIDEiB1ALD2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000369571; ENSP00000358584; ENSG00000134262
UCSCiuc057jot.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000134262.12
HGNCiHGNC:572 AP4B1
OpenTargetsiENSG00000134262
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1061 Eukaryota
COG5096 LUCA
GeneTreeiENSGT00530000063138
HOGENOMiHOG000294128
HOVERGENiHBG091836

Gene expression databases

BgeeiENSG00000134262 Expressed in 201 organ(s), highest expression level in right hemisphere of cerebellum
ExpressionAtlasiB1ALD2 baseline and differential

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR026739 AP_beta
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
PANTHERiPTHR11134 PTHR11134, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB1ALD2_HUMAN
AccessioniPrimary (citable) accession number: B1ALD2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 12, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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