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Protein

Transmembrane protein FAM155A

Gene

FAM155A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • calcium ion import across plasma membrane Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein FAM155A
Gene namesi
Name:FAM155A
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000204442.3
HGNCiHGNC:33877 FAM155A
neXtProtiNX_B1AL88

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21
Transmembranei417 – 437HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi728215
OpenTargetsiENSG00000204442
PharmGKBiPA162386676

Polymorphism and mutation databases

BioMutaiFAM155A

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003393731 – 458Transmembrane protein FAM155AAdd BLAST458

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi217N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

EPDiB1AL88
PaxDbiB1AL88
PRIDEiB1AL88
ProteomicsDBi3138

PTM databases

iPTMnetiB1AL88
PhosphoSitePlusiB1AL88

Expressioni

Gene expression databases

BgeeiENSG00000204442 Expressed in 136 organ(s), highest expression level in primary visual cortex
CleanExiHS_FAM155A
GenevisibleiB1AL88 HS

Organism-specific databases

HPAiHPA039453
HPA058768

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000365080

Structurei

3D structure databases

ProteinModelPortaliB1AL88
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi73 – 95Poly-GlnAdd BLAST23
Compositional biasi136 – 145Poly-Gly10

Sequence similaritiesi

Belongs to the FAM155 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IKAJ Eukaryota
ENOG410ZYWZ LUCA
GeneTreeiENSGT00390000006985
HOGENOMiHOG000090197
HOVERGENiHBG107868
InParanoidiB1AL88
OMAiSPDNLNC
OrthoDBiEOG091G07ZK
PhylomeDBiB1AL88
TreeFamiTF331752

Family and domain databases

InterProiView protein in InterPro
IPR029604 FAM155
PANTHERiPTHR15819:SF9 PTHR15819:SF9, 1 hit

Sequencei

Sequence statusi: Complete.

B1AL88-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTRGAWMCRQ YDDGLKIWLA APRENEKPFI DSERAQKWRL SLASLLFFTV
60 70 80 90 100
LLSDHLWFCA EAKLTRARDK EHQQQQRQQQ QQQQQQRQRQ QQQQQRRQQE
110 120 130 140 150
PSWPALLASM GESSPAAQAH RLLSASSSPT LPPSPGDGGG GGGKGNRGKD
160 170 180 190 200
DRGKALFLGN SAKPVWRLET CYPQGASSGQ CFTVENADAV CARNWSRGAA
210 220 230 240 250
GGDGQEVRSK HPTPLWNLSD FYLSFCNSYT LWELFSGLSS PNTLNCSLDV
260 270 280 290 300
VLKEGGEMTT CRQCVEAYQD YDHHAQEKYE EFESVLHKYL QSEEYSVKSC
310 320 330 340 350
PEDCKIVYKA WLCSQYFEVT QFNCRKTIPC KQYCLEVQTR CPFILPDNDE
360 370 380 390 400
VIYGGLSSFI CTGLYETFLT NDEPECCDVR REEKSNNPSK GTVEKSGSCH
410 420 430 440 450
RTSLTVSSAT RLCNSRLKLC VLVLILLHTV LTASAAQNTA GLSFGGINTL

EENSTNEE
Length:458
Mass (Da):51,493
Last modified:April 8, 2008 - v1
Checksum:iFA15D8280AE497D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295445 mRNA Translation: BAH12070.1
AL138914 Genomic DNA No translation available.
AL445204 Genomic DNA No translation available.
AL136964 Genomic DNA No translation available.
BC146878 mRNA Translation: AAI46879.1
BC157830 mRNA Translation: AAI57831.1
BC157855 mRNA Translation: AAI57856.1
BC157862 mRNA Translation: AAI57863.1
CCDSiCCDS32006.1
RefSeqiNP_001073865.1, NM_001080396.2
UniGeneiHs.535394

Genome annotation databases

EnsembliENST00000375915; ENSP00000365080; ENSG00000204442
GeneIDi728215
KEGGihsa:728215
UCSCiuc001vql.4 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295445 mRNA Translation: BAH12070.1
AL138914 Genomic DNA No translation available.
AL445204 Genomic DNA No translation available.
AL136964 Genomic DNA No translation available.
BC146878 mRNA Translation: AAI46879.1
BC157830 mRNA Translation: AAI57831.1
BC157855 mRNA Translation: AAI57856.1
BC157862 mRNA Translation: AAI57863.1
CCDSiCCDS32006.1
RefSeqiNP_001073865.1, NM_001080396.2
UniGeneiHs.535394

3D structure databases

ProteinModelPortaliB1AL88
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000365080

PTM databases

iPTMnetiB1AL88
PhosphoSitePlusiB1AL88

Polymorphism and mutation databases

BioMutaiFAM155A

Proteomic databases

EPDiB1AL88
PaxDbiB1AL88
PRIDEiB1AL88
ProteomicsDBi3138

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000375915; ENSP00000365080; ENSG00000204442
GeneIDi728215
KEGGihsa:728215
UCSCiuc001vql.4 human

Organism-specific databases

CTDi728215
DisGeNETi728215
EuPathDBiHostDB:ENSG00000204442.3
GeneCardsiFAM155A
HGNCiHGNC:33877 FAM155A
HPAiHPA039453
HPA058768
neXtProtiNX_B1AL88
OpenTargetsiENSG00000204442
PharmGKBiPA162386676
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IKAJ Eukaryota
ENOG410ZYWZ LUCA
GeneTreeiENSGT00390000006985
HOGENOMiHOG000090197
HOVERGENiHBG107868
InParanoidiB1AL88
OMAiSPDNLNC
OrthoDBiEOG091G07ZK
PhylomeDBiB1AL88
TreeFamiTF331752

Miscellaneous databases

ChiTaRSiFAM155A human
GenomeRNAii728215
PROiPR:B1AL88

Gene expression databases

BgeeiENSG00000204442 Expressed in 136 organ(s), highest expression level in primary visual cortex
CleanExiHS_FAM155A
GenevisibleiB1AL88 HS

Family and domain databases

InterProiView protein in InterPro
IPR029604 FAM155
PANTHERiPTHR15819:SF9 PTHR15819:SF9, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF155A_HUMAN
AccessioniPrimary (citable) accession number: B1AL88
Secondary accession number(s): B2RUV1, B7Z334
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: April 8, 2008
Last modified: November 7, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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