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UniProtKB - B1AKQ2 (B1AKQ2_HUMAN)
Protein
Submitted name:
Serine/threonine-protein kinase mTOR
Gene
MTOR
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- protein serine/threonine kinase activity Source: InterPro
Keywordsi
Molecular function | KinasePROSITE-ProRule annotationARBA annotation, Transferase |
Names & Taxonomyi
Protein namesi | Submitted name: Serine/threonine-protein kinase mTORImported |
Gene namesi | Name:MTORImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:3942, MTOR |
VEuPathDBi | HostDB:ENSG00000198793 |
PTM / Processingi
Proteomic databases
MaxQBi | B1AKQ2 |
PeptideAtlasi | B1AKQ2 |
PRIDEi | B1AKQ2 |
ProteomicsDBi | 3091 |
Expressioni
Gene expression databases
Bgeei | ENSG00000198793, Expressed in testis and 180 other tissues |
ExpressionAtlasi | B1AKQ2, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 80 | PI3K/PI4KInterPro annotationAdd BLAST | 80 |
Phylogenomic databases
GeneTreei | ENSGT00930000151037 |
HOGENOMi | CLU_126120_0_0_1 |
OMAi | VDPVFDC |
Family and domain databases
Gene3Di | 1.10.1070.11, 1 hit |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000403, PI3/4_kinase_cat_dom IPR036940, PI3/4_kinase_cat_sf IPR026683, TOR |
PANTHERi | PTHR11139:SF9, PTHR11139:SF9, 1 hit |
Pfami | View protein in Pfam PF00454, PI3_PI4_kinase, 1 hit |
SMARTi | View protein in SMART SM00146, PI3Kc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50290, PI3_4_KINASE_3, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
B1AKQ2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLDRLSGKIL HIDFGDCFEV AMTREKFPEK IPFRLTRMLT NAMEVTGLDG
60 70 80 90 100
NYRITCHTVM EVLREHKDSV MAVLEAFVYD PLLNWRLMDT NTKGNKRSRT
110 120 130 140 150
RTDSYSAGQS VEILDGVELG EPAHKKTGTT VPESIHSFIG DGLVKPEALN
160
KKAIQIINRV R
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP42345 | MTOR_HUMAN | Serine/threonine-protein kinase mTO... | MTOR FRAP, FRAP1, FRAP2, RAFT1, RAPT1 | 2,549 | Annotation score: | ||
B1AKP8 | B1AKP8_HUMAN | Non-specific serine/threonine prote... | MTOR | 754 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 161 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL049653 Genomic DNA No translation available. AL109811 Genomic DNA No translation available. AL391561 Genomic DNA No translation available. KF495866 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000455339; ENSP00000398745; ENSG00000198793 |
UCSCi | uc057cfw.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL049653 Genomic DNA No translation available. AL109811 Genomic DNA No translation available. AL391561 Genomic DNA No translation available. KF495866 Genomic DNA No translation available. |
3D structure databases
SMRi | B1AKQ2 |
ModBasei | Search... |
Proteomic databases
MaxQBi | B1AKQ2 |
PeptideAtlasi | B1AKQ2 |
PRIDEi | B1AKQ2 |
ProteomicsDBi | 3091 |
Protocols and materials databases
Antibodypediai | 3566, 1798 antibodies from 52 providers |
Genome annotation databases
Ensembli | ENST00000455339; ENSP00000398745; ENSG00000198793 |
UCSCi | uc057cfw.1, human |
Organism-specific databases
HGNCi | HGNC:3942, MTOR |
OpenTargetsi | ENSG00000198793 |
VEuPathDBi | HostDB:ENSG00000198793 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00930000151037 |
HOGENOMi | CLU_126120_0_0_1 |
OMAi | VDPVFDC |
Miscellaneous databases
ChiTaRSi | MTOR, human |
Gene expression databases
Bgeei | ENSG00000198793, Expressed in testis and 180 other tissues |
ExpressionAtlasi | B1AKQ2, baseline and differential |
Family and domain databases
Gene3Di | 1.10.1070.11, 1 hit |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000403, PI3/4_kinase_cat_dom IPR036940, PI3/4_kinase_cat_sf IPR026683, TOR |
PANTHERi | PTHR11139:SF9, PTHR11139:SF9, 1 hit |
Pfami | View protein in Pfam PF00454, PI3_PI4_kinase, 1 hit |
SMARTi | View protein in SMART SM00146, PI3Kc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50290, PI3_4_KINASE_3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | B1AKQ2_HUMAN | |
Accessioni | B1AKQ2Primary (citable) accession number: B1AKQ2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 8, 2008 |
Last sequence update: | April 8, 2008 | |
Last modified: | January 19, 2022 | |
This is version 97 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |