UniProtKB - B1AKN3 (B1AKN3_HUMAN)
Protein
Submitted name:
Arginine-glutamic acid dipeptide (RE) repeats, isoform CRA_b
Gene
RERE
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- sequence-specific DNA binding Source: InterPro
- zinc ion binding Source: InterPro
GO - Biological processi
- regulation of transcription, DNA-templated Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Arginine-glutamic acid dipeptide (RE) repeats, isoform CRA_bImportedSubmitted name: Arginine-glutamic acid dipeptide repeats proteinImported |
Gene namesi | Name:REREImported ORF Names:hCG_2008872Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000142599.17 |
HGNCi | HGNC:9965, RERE |
Subcellular locationi
Nucleus
- nucleus Source: UniProtKB-KW
Keywords - Cellular componenti
NucleusARBA annotationPTM / Processingi
Keywords - PTMi
AcetylationARBA annotation, PhosphoproteinARBA annotationProteomic databases
MaxQBi | B1AKN3 |
PRIDEi | B1AKN3 |
ProteomicsDBi | 3082 |
Expressioni
Gene expression databases
Bgeei | ENSG00000142599, Expressed in corpus callosum and 250 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 119 | ELM2InterPro annotationAdd BLAST | 104 | |
Domaini | 123 – 175 | SANTInterPro annotationAdd BLAST | 53 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 32 | DisorderedSequence analysisAdd BLAST | 32 | |
Regioni | 196 – 227 | DisorderedSequence analysisAdd BLAST | 32 | |
Regioni | 274 – 865 | DisorderedSequence analysisAdd BLAST | 592 | |
Regioni | 894 – 978 | DisorderedSequence analysisAdd BLAST | 85 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 196 – 218 | PolarSequence analysisAdd BLAST | 23 | |
Compositional biasi | 288 – 303 | PolyampholyteSequence analysisAdd BLAST | 16 | |
Compositional biasi | 328 – 358 | PolarSequence analysisAdd BLAST | 31 | |
Compositional biasi | 359 – 402 | PolyampholyteSequence analysisAdd BLAST | 44 | |
Compositional biasi | 403 – 419 | PolarSequence analysisAdd BLAST | 17 | |
Compositional biasi | 420 – 439 | PolyampholyteSequence analysisAdd BLAST | 20 | |
Compositional biasi | 440 – 480 | PolarSequence analysisAdd BLAST | 41 | |
Compositional biasi | 481 – 505 | Pro-richSequence analysisAdd BLAST | 25 | |
Compositional biasi | 506 – 528 | PolarSequence analysisAdd BLAST | 23 | |
Compositional biasi | 539 – 561 | Pro-richSequence analysisAdd BLAST | 23 | |
Compositional biasi | 608 – 644 | PolarSequence analysisAdd BLAST | 37 | |
Compositional biasi | 645 – 681 | Pro-richSequence analysisAdd BLAST | 37 | |
Compositional biasi | 712 – 797 | Pro-richSequence analysisAdd BLAST | 86 | |
Compositional biasi | 894 – 942 | PolyampholyteSequence analysisAdd BLAST | 49 |
Phylogenomic databases
GeneTreei | ENSGT00940000153615 |
Family and domain databases
CDDi | cd00202, ZnF_GATA, 1 hit |
InterProi | View protein in InterPro IPR002951, Atrophin-like IPR000949, ELM2_dom IPR009057, Homeobox-like_sf IPR001005, SANT/Myb IPR017884, SANT_dom IPR000679, Znf_GATA |
Pfami | View protein in Pfam PF03154, Atrophin-1, 1 hit PF01448, ELM2, 1 hit PF00320, GATA, 1 hit |
SMARTi | View protein in SMART SM01189, ELM2, 1 hit SM00717, SANT, 1 hit SM00401, ZnF_GATA, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS51156, ELM2, 1 hit PS51293, SANT, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All
B1AKN3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDDPFSPCRR LNSTQGEIRV GPSHQAKLPD LQPFPSPDGD TVTQHEELVW
60 70 80 90 100
MPGVNDCDLL MYLRAARSMA AFAGMCDGGS TEDGCVAASR DDTTLNALNT
110 120 130 140 150
LHESGYDAGK ALQRLVKKPV PKLIEKCWTE DEVKRFVKGL RQYGKNFFRI
160 170 180 190 200
RKELLPNKET GELITFYYYW KKTPEAASSR AHRRHRRQAV FRRIKTRTAS
210 220 230 240 250
TPVNTPSRPP SSEFLDLSSA SEDDFDSEDS EQELKGYACR HCFTTTSKDW
260 270 280 290 300
HHGGRENILL CTDCRIHFKK YGELPPIEKP VDPPPFMFKP VKEEDDGLSG
310 320 330 340 350
KHSMRTRRSR GSMSTLRSGR KKQPASPDGR TSPINEDIRS SGRNSPSAAS
360 370 380 390 400
TSSNDSKAET VKKSAKKVKE EASSPLKSNK RQREKVASDT EEADRTSSKK
410 420 430 440 450
TKTQEISRPN SPSEGEGESS DSRSVNDEGS SDPKDIDQDN RSTSPSIPSP
460 470 480 490 500
QDNESDSDSS AQQQMLQAQP PALQAPTGVT PAPSSAPPGT PQLPTPGPTP
510 520 530 540 550
SATAVPPQGS PTASQAPNQP QAPTAPVPHT HIQQAPALHP QRPPSPHPPP
560 570 580 590 600
HPSPHPPLQP LTGSAGQPSA PSHAQPPLHG QGPPGPHSLQ AGPLLQHPGP
610 620 630 640 650
PQPFGLPPQA SQGQAPLGTS PAAAYPHTSL QLPASQSALQ SQQPPREQPL
660 670 680 690 700
PPAPLAMPHI KPPPTTPIPQ LPAPQAHKHP PHLSGPSPFS MNANLPPPPA
710 720 730 740 750
LKPLSSLSTH HPPSAHPPPL QLMPQSQPLP SSPAQPPGLT QSQNLPPPPA
760 770 780 790 800
SHPPTGLHQV APQPPFAQHP FVPGGPPPIT PPTCPSTSTP PAGPGTSAQP
810 820 830 840 850
PCSGAAASGG SIAGGSSCPL PTVQIKEEAL DDAEEPESPP PPPRSPSPEP
860 870 880 890 900
TVVDTPSHAS QSARFYKHLD RGYNSCARTD LYFMPLAGSK LAKKREEAIE
910 920 930 940 950
KAKREAEQKA REEREREKEK EKERERERER EREAERAAKA SSSAHEGRLS
960 970 980 990 1000
DPQLSGPGHM RPSFEPPPTT IAAVPPYIGP DTPALRTLSE YARPHVMSPT
1010 1020 1030 1040 1050
NRNHPFYMPL NPTDPLLAYH MPGLYNVDPT IRERELRERE IREREIRERE
1060 1070 1080 1090 1100
LRERMKPGFE VKPPELDPLH PAANPMEHFA RHSALTIPPT AGPHPFASFH
1110 1120 1130 1140 1150
PGLNPLERER LALAGPQLRP EMSYPDRLAA ERIHAERMAS LTSDPLARLQ
1160 1170 1180 1190 1200
MFNVTPHHHQ HSHIHSHLHL HQQDPLHQGS AGPVHPLVDP LTAGPHLARF
1210 1220 1230 1240 1250
PYPPGTLPNP LLGQPPHEHE MLRHPVFGTP YPRDLPGAIP PPMSAAHQLQ
1260 1270 1280 1290
AMHAQSAELQ RLAMEQQWLH GHPHMHGGHL PSQEDYYSRL KKEGDKQL
Computationally mapped potential isoform sequencesi
There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9P2R6 | RERE_HUMAN | Arginine-glutamic acid dipeptide re... | RERE ARG, ARP, ATN1L, KIAA0458 | 1,566 | Annotation score: | ||
A0A590UJ84 | A0A590UJ84_HUMAN | Arginine-glutamic acid dipeptide re... | RERE | 783 | Annotation score: | ||
H7BYW9 | H7BYW9_HUMAN | Arginine-glutamic acid dipeptide re... | RERE | 584 | Annotation score: | ||
A0A075B770 | A0A075B770_HUMAN | Arginine-glutamic acid dipeptide re... | RERE | 213 | Annotation score: | ||
A0A590UK57 | A0A590UK57_HUMAN | Arginine-glutamic acid dipeptide re... | RERE | 402 | Annotation score: | ||
D6RA28 | D6RA28_HUMAN | Arginine-glutamic acid dipeptide re... | RERE | 177 | Annotation score: | ||
K7EIQ4 | K7EIQ4_HUMAN | Arginine-glutamic acid dipeptide re... | RERE | 26 | Annotation score: | ||
H0Y975 | H0Y975_HUMAN | Arginine-glutamic acid dipeptide re... | RERE | 91 | Annotation score: | ||
K7EIE3 | K7EIE3_HUMAN | Arginine-glutamic acid dipeptide re... | RERE | 89 | Annotation score: | ||
K7EJQ1 | K7EJQ1_HUMAN | Arginine-glutamic acid dipeptide re... | RERE | 35 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL096855 Genomic DNA No translation available. AL356072 Genomic DNA No translation available. AL357552 Genomic DNA No translation available. AL357713 Genomic DNA No translation available. KF495857 Genomic DNA No translation available. KF495858 Genomic DNA No translation available. KF510737 Genomic DNA No translation available. CH471130 Genomic DNA Translation: EAW71599.1 |
RefSeqi | XP_005263523.1, XM_005263466.1 |
Genome annotation databases
Ensembli | ENST00000377464; ENSP00000366684; ENSG00000142599 |
UCSCi | uc010nzx.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL096855 Genomic DNA No translation available. AL356072 Genomic DNA No translation available. AL357552 Genomic DNA No translation available. AL357713 Genomic DNA No translation available. KF495857 Genomic DNA No translation available. KF495858 Genomic DNA No translation available. KF510737 Genomic DNA No translation available. CH471130 Genomic DNA Translation: EAW71599.1 |
RefSeqi | XP_005263523.1, XM_005263466.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | B1AKN3 |
PRIDEi | B1AKN3 |
ProteomicsDBi | 3082 |
Protocols and materials databases
Antibodypediai | 13215, 156 antibodies |
Genome annotation databases
Ensembli | ENST00000377464; ENSP00000366684; ENSG00000142599 |
UCSCi | uc010nzx.2, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000142599.17 |
HGNCi | HGNC:9965, RERE |
OpenTargetsi | ENSG00000142599 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000153615 |
Miscellaneous databases
BioGRID-ORCSi | 473, 13 hits in 869 CRISPR screens |
ChiTaRSi | RERE, human |
GenomeRNAii | 473 |
Gene expression databases
Bgeei | ENSG00000142599, Expressed in corpus callosum and 250 other tissues |
Family and domain databases
CDDi | cd00202, ZnF_GATA, 1 hit |
InterProi | View protein in InterPro IPR002951, Atrophin-like IPR000949, ELM2_dom IPR009057, Homeobox-like_sf IPR001005, SANT/Myb IPR017884, SANT_dom IPR000679, Znf_GATA |
Pfami | View protein in Pfam PF03154, Atrophin-1, 1 hit PF01448, ELM2, 1 hit PF00320, GATA, 1 hit |
SMARTi | View protein in SMART SM01189, ELM2, 1 hit SM00717, SANT, 1 hit SM00401, ZnF_GATA, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS51156, ELM2, 1 hit PS51293, SANT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B1AKN3_HUMAN | |
Accessioni | B1AKN3Primary (citable) accession number: B1AKN3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 8, 2008 |
Last sequence update: | April 8, 2008 | |
Last modified: | December 2, 2020 | |
This is version 117 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |