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Protein
Submitted name:

Mitotic spindle assembly checkpoint protein MAD2B

Gene

MAD2L2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Mitotic spindle assembly checkpoint protein MAD2BImported
Gene namesi
Name:MAD2L2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000116670.14
HGNCiHGNC:6764 MAD2L2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000116670

PTM / Processingi

Proteomic databases

MaxQBiB1AK45
PeptideAtlasiB1AK45
PRIDEiB1AK45

Expressioni

Gene expression databases

BgeeiENSG00000116670 Expressed in 182 organ(s), highest expression level in testis
ExpressionAtlasiB1AK45 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB1AK45
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 167HORMAInterPro annotationAdd BLAST155

Phylogenomic databases

eggNOGiKOG3186 Eukaryota
ENOG4111I7Q LUCA
GeneTreeiENSGT00500000044946
HOGENOMiHOG000231083
HOVERGENiHBG052443

Family and domain databases

Gene3Di3.30.900.10, 1 hit
InterProiView protein in InterPro
IPR003511 HORMA_dom
IPR036570 HORMA_dom_sf
PfamiView protein in Pfam
PF02301 HORMA, 1 hit
SUPFAMiSSF56019 SSF56019, 1 hit
PROSITEiView protein in PROSITE
PS50815 HORMA, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

B1AK45-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTLTRQDLN FGQVVADVLC EFLEVAVHLI LYVREVYPVG IFQKRKKYNV
60 70 80 90 100
PVQMSCHPEL NQYIQDTLHC VKPLLEKNDV EKVVVVILDK EHRPVEKFVF
110 120 130 140 150
EITQPPLLSI SSDSLLSHVE QLLRAFILKI SVCDAVLDHN PPGCTFTVLV
160
HTREAATRNM EKIQVIK
Length:167
Mass (Da):19,146
Last modified:April 8, 2008 - v1
Checksum:i5AEE896A8BE1DD34
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UI95MD2L2_HUMAN
Mitotic spindle assembly checkpoint...
MAD2L2 MAD2B, REV7
211Annotation score:
B1AK44B1AK44_HUMAN
Mitotic spindle assembly checkpoint...
MAD2L2
224Annotation score:
B1AK43B1AK43_HUMAN
Mitotic spindle assembly checkpoint...
MAD2L2
197Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei167Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL031731 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000456915; ENSP00000400982; ENSG00000116670
UCSCiuc057cgu.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL031731 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliB1AK45
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB1AK45
PeptideAtlasiB1AK45
PRIDEiB1AK45

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000456915; ENSP00000400982; ENSG00000116670
UCSCiuc057cgu.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000116670.14
HGNCiHGNC:6764 MAD2L2
OpenTargetsiENSG00000116670
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3186 Eukaryota
ENOG4111I7Q LUCA
GeneTreeiENSGT00500000044946
HOGENOMiHOG000231083
HOVERGENiHBG052443

Miscellaneous databases

ChiTaRSiMAD2L2 human

Gene expression databases

BgeeiENSG00000116670 Expressed in 182 organ(s), highest expression level in testis
ExpressionAtlasiB1AK45 baseline and differential

Family and domain databases

Gene3Di3.30.900.10, 1 hit
InterProiView protein in InterPro
IPR003511 HORMA_dom
IPR036570 HORMA_dom_sf
PfamiView protein in Pfam
PF02301 HORMA, 1 hit
SUPFAMiSSF56019 SSF56019, 1 hit
PROSITEiView protein in PROSITE
PS50815 HORMA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB1AK45_HUMAN
AccessioniPrimary (citable) accession number: B1AK45
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 12, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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