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UniProtKB - B1AJS0 (B1AJS0_HUMAN)

Entry version 106 (12 Aug 2020)
Sequence version 1 (08 Apr 2008)
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Protein

Protein-tyrosine-phosphatase

Gene

PTPRT

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei1074Phosphocysteine intermediatePROSITE-ProRule annotation1
Active sitei1368Phosphocysteine intermediatePROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protein phosphataseARBA annotation, ReceptorARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein-tyrosine-phosphataseARBA annotation (EC:3.1.3.48ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PTPRTImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000196090.12

Human Gene Nomenclature Database

More...HGNCi		HGNC:9682, PTPRT

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei747 – 768HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000196090

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500276040926 – 1431Protein-tyrosine-phosphataseSequence analysisAdd BLAST1406

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		B1AJS0

PRoteomics IDEntifications database

More...PRIDEi		B1AJS0

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		2985

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000196090, Expressed in middle temporal gyrus and 108 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		B1AJS0, baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini30 – 191MAMInterPro annotationAdd BLAST162
Domaini193 – 284Ig-likeInterPro annotationAdd BLAST92
Domaini291 – 384Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini389 – 483Fibronectin type-IIIInterPro annotationAdd BLAST95
Domaini484 – 590Fibronectin type-IIIInterPro annotationAdd BLAST107
Domaini879 – 1133Tyrosine-protein phosphataseInterPro annotationAdd BLAST255
Domaini1053 – 1124TYR_PHOSPHATASE_2InterPro annotationAdd BLAST72
Domaini1165 – 1427Tyrosine-protein phosphataseInterPro annotationAdd BLAST263
Domaini1341 – 1418TYR_PHOSPHATASE_2InterPro annotationAdd BLAST78

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni777 – 836DisorderedSequence analysisAdd BLAST60

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi797 – 836PolarSequence analysisAdd BLAST40

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.ARBA annotation

Keywords - Domaini

Immunoglobulin domainARBA annotation, SignalSequence analysisARBA annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155326

Database of Orthologous Groups

More...OrthoDBi		411281at2759

Family and domain databases

Conserved Domains Database

More...CDDi		cd00063, FN3, 3 hits
cd06263, MAM, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.10, 4 hits
3.90.190.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR000998, MAM_dom
IPR029021, Prot-tyrosine_phosphatase-like
IPR000242, PTPase_domain
IPR016130, Tyr_Pase_AS
IPR003595, Tyr_Pase_cat
IPR000387, TYR_PHOSPHATASE_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00041, fn3, 2 hits
PF00629, MAM, 1 hit
PF00102, Y_phosphatase, 2 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00020, MAMDOMAIN
PR00700, PRTYPHPHTASE

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00060, FN3, 3 hits
SM00137, MAM, 1 hit
SM00194, PTPc, 2 hits
SM00404, PTPc_motif, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48726, SSF48726, 1 hit
SSF49265, SSF49265, 2 hits
SSF49899, SSF49899, 1 hit
SSF52799, SSF52799, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50853, FN3, 3 hits
PS50835, IG_LIKE, 1 hit
PS00740, MAM_1, 1 hit
PS50060, MAM_2, 1 hit
PS00383, TYR_PHOSPHATASE_1, 2 hits
PS50056, TYR_PHOSPHATASE_2, 2 hits
PS50055, TYR_PHOSPHATASE_PTP, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

B1AJS0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASLAALALS LLLRLQLPPL PGARAQSAAG GCSFDEHYSN CGYSVALGTN 
        60         70         80         90        100
GFTWEQINTW EKPMLDQAVP TGSFMMVNSS GRASGQKAHL LLPTLKENDT 
       110        120        130        140        150
HCIDFHYYFS SRDRSSPGAL NVYVKVNGGP QGNPVWNVSG VVTEGWVKAE 
       160        170        180        190        200
LAISTFWPHF YQVIFESVSL KGHPGYIAVD EVRVLAHPCR KAPHFLRLQN 
       210        220        230        240        250
VEVNVGQNAT FQCIAGGKWS QHDKLWLQQW NGRDTALMVT RVVNHRRFSA 
       260        270        280        290        300
TVSVADTAQR SVSKYRCVIR SDGGSGVSNY AELIVKEPPT PIAPPELLAV 
       310        320        330        340        350
GATYLWIKPN ANSIIGDGPI ILKEVEYRTT TGTWAETHIV DSPNYKLWHL 
       360        370        380        390        400
DPDVEYEIRV LLTRPGEGGT GPPGPPLTTR TKCADPVHGP QNVEIVDIRA 
       410        420        430        440        450
RQLTLQWEPF GYAVTRCHSY NLTVQYQYVF NQQQYEAEEV IQTSSHYTLR 
       460        470        480        490        500
GLRPFMTIRL RLLLSNPEGR MESEELVVQT EEDVPGAVPL ESIQGGPFEE 
       510        520        530        540        550
KIYIQWKPPN ETNGVITLYE INYKAVGSLD PSADLSSQRG KVFKLRNETH 
       560        570        580        590        600
HLFVGLYPGT TYSFTIKAST AKGFGPPVTT RIATKISAPS MPEYDTDTPL 
       610        620        630        640        650
NETDTTITVM LKPAQSRGAP VSVYQLVVKE ERLQKSRRAA DIIECFSVPV 
       660        670        680        690        700
SYRNASSLDS LHYFAAELKP ANLPVTQPFT VGDNKTYNGY WNPPLSPLKS 
       710        720        730        740        750
YSIYFQALSK ANGETKINCV RLATKGASTQ NSNTVEPEKQ VDNTVKMAGV 
       760        770        780        790        800
IAGLLMFIII LLGVMLTIKR RKLAKKQKET QSGAQREMGP VASADKPTTK 
       810        820        830        840        850
LSASRNDEGF SSSSQDVNGF TDGSRGELSQ PTLTIQTHPY RTCDPVEMSY 
       860        870        880        890        900
PRDQFQPAIR VADLLQHITQ MKRGQGYGFK EEYEALPEGQ TASWDTAKED 
       910        920        930        940        950
ENRNKNRYGN IISYDHSRVR LLVLDGDPHS DYINANYIDG YHRPRHYIAT 
       960        970        980        990       1000
QGPMQETVKD FWRMIWQENS ASIVMVTNLV EVGRVKCVRY WPDDTEVYGD 
      1010       1020       1030       1040       1050
IKVTLIETEP LAEYVIRTFT VQKKGYHEIR ELRLFHFTSW PDHGVPCYAT 
      1060       1070       1080       1090       1100
GLLGFVRQVK FLNPPEAGPI VVHCSAGAGR TGCFIAIDTM LDMAENEGVV 
      1110       1120       1130       1140       1150
DIFNCVRELR AQRVNLVQTE EQYVFVHDAI LEACLCGNTA IPVCEFRSLY 
      1160       1170       1180       1190       1200
YNISRLDPQT NSSQIKDEFQ TLNIVTPRVR PEDCSIGLLP RNHDKNRSMD 
      1210       1220       1230       1240       1250
VLPLDRCLPF LISVDGESSN YINAALMDSH KQPAAFVVTQ HPLPNTVADF 
      1260       1270       1280       1290       1300
WRLVFDYNCS SVVMLNEMDT AQFCMQYWPE KTSGCYGPIQ VEFVSADIDE 
      1310       1320       1330       1340       1350
DIIHRIFRIC NMARPQDGYR IVQHLQYIGW PAYRDTPPSK RSLLKVVRRL 
      1360       1370       1380       1390       1400
EKWQEQYDGR EGRTVVHCLN GGGRSGTFCA ICSVCEMIQQ QNIIDVFHIV 
      1410       1420       1430 
KTLRNNKSNM VETLEQYKFV YEVALEYLSS F
Length:1,431
Mass (Da):160,853
Last modified:April 8, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB72B41AE356A7510
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O14522PTPRT_HUMAN
Receptor-type tyrosine-protein phos...
PTPRT KIAA0283
1,441Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A075B6H0A0A075B6H0_HUMAN
Protein-tyrosine-phosphatase
PTPRT
1,460Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1AJR9B1AJR9_HUMAN
Protein-tyrosine-phosphatase
PTPRT
1,451Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1AJR8B1AJR8_HUMAN
Protein-tyrosine-phosphatase
PTPRT
1,450Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1AJR6B1AJR6_HUMAN
Protein-tyrosine-phosphatase
PTPRT
1,440Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WY22A0A087WY22_HUMAN
Protein-tyrosine-phosphatase
PTPRT
1,059Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X1X2A0A087X1X2_HUMAN
Protein-tyrosine-phosphatase
PTPRT
1,076Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WWD6A0A087WWD6_HUMAN
Receptor-type tyrosine-protein phos...
PTPRT
313Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X1J1A0A087X1J1_HUMAN
Receptor-type tyrosine-protein phos...
PTPRT
47Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL022239 Genomic DNA No translation available.
AL024473 Genomic DNA No translation available.
AL035459 Genomic DNA No translation available.
AL049812 Genomic DNA No translation available.
AL109826 Genomic DNA No translation available.
KF456906 Genomic DNA No translation available.
KF456910 Genomic DNA No translation available.
Z93942 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000373201; ENSP00000362297; ENSG00000196090

UCSC genome browser

More...UCSCi		uc061xcc.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL022239 Genomic DNA No translation available.
AL024473 Genomic DNA No translation available.
AL035459 Genomic DNA No translation available.
AL049812 Genomic DNA No translation available.
AL109826 Genomic DNA No translation available.
KF456906 Genomic DNA No translation available.
KF456910 Genomic DNA No translation available.
Z93942 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

MaxQBiB1AJS0
PRIDEiB1AJS0
ProteomicsDBi2985

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2780, 107 antibodies

Genome annotation databases

EnsembliENST00000373201; ENSP00000362297; ENSG00000196090
UCSCiuc061xcc.1, human

Organism-specific databases

EuPathDBiHostDB:ENSG00000196090.12
HGNCiHGNC:9682, PTPRT
OpenTargetsiENSG00000196090

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

GeneTreeiENSGT00940000155326
OrthoDBi411281at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		PTPRT, human

Gene expression databases

BgeeiENSG00000196090, Expressed in middle temporal gyrus and 108 other tissues
ExpressionAtlasiB1AJS0, baseline and differential

Family and domain databases

CDDicd00063, FN3, 3 hits
cd06263, MAM, 1 hit
Gene3Di2.60.40.10, 4 hits
3.90.190.10, 2 hits
InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR000998, MAM_dom
IPR029021, Prot-tyrosine_phosphatase-like
IPR000242, PTPase_domain
IPR016130, Tyr_Pase_AS
IPR003595, Tyr_Pase_cat
IPR000387, TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00041, fn3, 2 hits
PF00629, MAM, 1 hit
PF00102, Y_phosphatase, 2 hits
PRINTSiPR00020, MAMDOMAIN
PR00700, PRTYPHPHTASE
SMARTiView protein in SMART
SM00060, FN3, 3 hits
SM00137, MAM, 1 hit
SM00194, PTPc, 2 hits
SM00404, PTPc_motif, 2 hits
SUPFAMiSSF48726, SSF48726, 1 hit
SSF49265, SSF49265, 2 hits
SSF49899, SSF49899, 1 hit
SSF52799, SSF52799, 2 hits
PROSITEiView protein in PROSITE
PS50853, FN3, 3 hits
PS50835, IG_LIKE, 1 hit
PS00740, MAM_1, 1 hit
PS50060, MAM_2, 1 hit
PS00383, TYR_PHOSPHATASE_1, 2 hits
PS50056, TYR_PHOSPHATASE_2, 2 hits
PS50055, TYR_PHOSPHATASE_PTP, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB1AJS0_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B1AJS0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: August 12, 2020
This is version 106 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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