UniProtKB - B1AHN3 (B1AHN3_HUMAN)
Protein
Submitted name:
Fibulin-1
Gene
FBLN1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Fibulin-1Imported |
Gene namesi | Name:FBLN1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:3600, FBLN1 |
VEuPathDBi | HostDB:ENSG00000077942.18 |
Subcellular locationi
Extracellular region or secreted
- extracellular region Source: UniProtKB-KW
Keywords - Cellular componenti
SecretedARBA annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 29 | Sequence analysisAdd BLAST | 29 | |
ChainiPRO_5002761385 | 30 – 172 | Sequence analysisAdd BLAST | 143 |
Keywords - PTMi
Disulfide bondARBA annotationProteomic databases
MaxQBi | B1AHN3 |
PeptideAtlasi | B1AHN3 |
PRIDEi | B1AHN3 |
ProteomicsDBi | 2968 |
Expressioni
Gene expression databases
Bgeei | ENSG00000077942, Expressed in endocervix and 230 other tissues |
ExpressionAtlasi | B1AHN3, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 36 – 69 | Anaphylatoxin-likeInterPro annotationAdd BLAST | 34 | |
Domaini | 77 – 110 | Anaphylatoxin-likeInterPro annotationAdd BLAST | 34 | |
Domaini | 112 – 144 | Anaphylatoxin-likeInterPro annotationAdd BLAST | 33 |
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000156642 |
HOGENOMi | CLU_1307294_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR000020, Anaphylatoxin/fibulin |
Pfami | View protein in Pfam PF01821, ANATO, 1 hit |
SMARTi | View protein in SMART SM00104, ANATO, 3 hits |
PROSITEi | View protein in PROSITE PS01177, ANAPHYLATOXIN_1, 1 hit PS01178, ANAPHYLATOXIN_2, 3 hits |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All
B1AHN3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MERAAPSRRV PLPLLLLGGL ALLAAGVDAD VLLEACCADG HRMATHQKDC
60 70 80 90 100
SLPYATESKE CRMVQEQCCH SQLEELHCAT GISLANEQDR CATPHGDNAS
110 120 130 140 150
LEATFVKRCC HCCLLGRAAQ AQGQSCEYSL MVGYQCGQVF QACCVKSQET
160 170
GDLDVGGLQE TGGGPCKQQC RD
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP23142 | FBLN1_HUMAN | Fibulin-1 | FBLN1 PP213 | 703 | Annotation score: | ||
B1AHL2 | B1AHL2_HUMAN | Fibulin-1 | FBLN1 | 721 | Annotation score: | ||
B1AHM8 | B1AHM8_HUMAN | Fibulin-1 | FBLN1 | 181 | Annotation score: | ||
H7C1M6 | H7C1M6_HUMAN | Fibulin-1 | FBLN1 | 183 | Annotation score: | ||
B1AHM9 | B1AHM9_HUMAN | Fibulin-1 | FBLN1 | 189 | Annotation score: | ||
B1AHM7 | B1AHM7_HUMAN | Fibulin-1 | FBLN1 | 139 | Annotation score: | ||
B1AHM5 | B1AHM5_HUMAN | Fibulin-1 | FBLN1 | 92 | Annotation score: | ||
B1AHM6 | B1AHM6_HUMAN | Fibulin-1 | FBLN1 | 65 | Annotation score: | ||
A0A0U1RRA4 | A0A0U1RRA4_HUMAN | Fibulin-1 | FBLN1 | 60 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 172 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL021391 Genomic DNA No translation available. KF457485 Genomic DNA No translation available. Z95331 Genomic DNA No translation available. Z98047 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000455233; ENSP00000402963; ENSG00000077942 |
UCSCi | uc062fcy.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL021391 Genomic DNA No translation available. KF457485 Genomic DNA No translation available. Z95331 Genomic DNA No translation available. Z98047 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | B1AHN3 |
PeptideAtlasi | B1AHN3 |
PRIDEi | B1AHN3 |
ProteomicsDBi | 2968 |
Protocols and materials databases
Antibodypediai | 886, 307 antibodies |
Genome annotation databases
Ensembli | ENST00000455233; ENSP00000402963; ENSG00000077942 |
UCSCi | uc062fcy.1, human |
Organism-specific databases
HGNCi | HGNC:3600, FBLN1 |
OpenTargetsi | ENSG00000077942 |
VEuPathDBi | HostDB:ENSG00000077942.18 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156642 |
HOGENOMi | CLU_1307294_0_0_1 |
Miscellaneous databases
ChiTaRSi | FBLN1, human |
Gene expression databases
Bgeei | ENSG00000077942, Expressed in endocervix and 230 other tissues |
ExpressionAtlasi | B1AHN3, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR000020, Anaphylatoxin/fibulin |
Pfami | View protein in Pfam PF01821, ANATO, 1 hit |
SMARTi | View protein in SMART SM00104, ANATO, 3 hits |
PROSITEi | View protein in PROSITE PS01177, ANAPHYLATOXIN_1, 1 hit PS01178, ANAPHYLATOXIN_2, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B1AHN3_HUMAN | |
Accessioni | B1AHN3Primary (citable) accession number: B1AHN3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 2, 2010 |
Last sequence update: | March 2, 2010 | |
Last modified: | February 10, 2021 | |
This is version 66 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |