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1 to 25 of 35  Show
  1. 1
    "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).

    This publication is cited by 8225 other entries.

  2. 2
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).
  3. 3
    "NEDO functional analysis of protein and research application project."
    Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
    Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Tissue: Tongue.
    Source: UniProtKB/TrEMBL (unreviewed).
  4. 4
    "Quantitation of CDC6 and MCM5 mRNA in cervical intraepithelial neoplasia and invasive squamous cell carcinoma of the cervix."
    Murphy N., Ring M., Heffron C.C., Martin C.M., McGuinness E., Sheils O., O'Leary J.J.
    Mod. Pathol. 18:844-849(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: Results further confirm the importance of MCM5 in malignant transformation and in the pathogenesis of cervical dysplasia.
    Source: GeneRIF:4174.

    This publication is mapped to 11 other entries.

  5. 5
    "The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation."
    Snyder M., He W., Zhang J.J.
    Proc. Natl. Acad. Sci. U.S.A. 102:14539-14544(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation.
    Source: GeneRIF:4174.

    This publication is mapped to 8 other entries.

  6. 6
    Category: Structure.
    Annotation: MCM5 is part of the GINS complex.
    Source: GeneRIF:4174.

    This publication is cited by 3 and mapped to 25 other entries.

  7. 7
    "Minichromosome maintenance proteins 2 and 5 in non-benign epithelial ovarian tumours: relationship with cell cycle regulators and prognostic implications."
    Gakiopoulou H., Korkolopoulou P., Levidou G., Thymara I., Saetta A., Piperi C., Givalos N., Vassilopoulos I., Ventouri K., Tsenga A., Bamias A., Dimopoulos M.A., Agapitos E., Patsouris E.
    Br. J. Cancer 97:1124-1134(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: MCM-2 and MCM-5 proteins appear to be promising as prognostic markers in patients with ovarian adenocarcinomas.
    Source: GeneRIF:4174.

    This publication is mapped to 13 other entries.

  8. 8
    "Expression of minichromosome maintenance 5 protein in proliferative and malignant skin diseases."
    Liu H., Takeuchi S., Moroi Y., Lin N., Urabe K., Kokuba H., Imafuku S., Dainichi T., Uchi H., Furue M., Tu Y.
    Int. J. Dermatol. 46:1171-1176(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Expression.
    Annotation: results demonstrate pattern and frequency of MCM5 expression in various skin diseases.
    Source: GeneRIF:4174.

    This publication is mapped to 8 other entries.

  9. 9
    "Application of flow cytometry for biomarker-based cervical cancer cells detection."
    Ling J., Wiederkehr U., Cabiness S., Shroyer K.R., Robinson J.P.
    Diagn. Cytopathol. 36:76-84(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Immunofluorescence technology to quantify cervical cell expression of two biomarkers p16(INK4A) and Mcm5 was developed and evaluated by both microscopy and flow cytometry.
    Source: GeneRIF:4174.

    This publication is mapped to 8 other entries.

  10. 10
    "Clinical significance of MCM-2 and MCM-5 expression in colon cancer: association with clinicopathological parameters and tumor proliferative capacity."
    Giaginis C., Georgiadou M., Dimakopoulou K., Tsourouflis G., Gatzidou E., Kouraklis G., Theocharis S.
    Dig. Dis. Sci. 54:282-291(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: No significant association was observed between MCM-5 protein expression and the clinicopathological characteristics of colon cancer examined.
    Source: GeneRIF:4174.

    This publication is mapped to 13 other entries.

  11. 11
    "Cyclin E-dependent localization of MCM5 regulates centrosome duplication."
    Ferguson R.L., Maller J.L.
    J. Cell. Sci. 121:3224-3232(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: Cyclin E is shown to directly interact with and colocalize on centrosomes with the DNA replication factor MCM5 in a centrosomal localization sequence-dependent but Cdk2-independent manner.
    Source: GeneRIF:4174.

    This publication is mapped to 8 other entries.

  12. 12
    "Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia."
    Enjuanes A., Benavente Y., Bosch F., Martin-Guerrero I., Colomer D., Perez-Alvarez S., Reina O., Ardanaz M.T., Jares P., Garcia-Orad A., Pujana M.A., Montserrat E., de Sanjose S., Campo E.
    Cancer Res. 68:10178-10186(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:4174.

    This publication is mapped to 1208 other entries.

  13. 13
    "Analysis of pRb, p16INK4A proteins and proliferating antigens: PCNA, Ki-67 and MCM5 expression in aggressive fibromatosis (desmoid tumor)."
    Stalinska L., Turant M., Tosik D., Sygut J., Kulig A., Kopczynski J., Dziki A., Ferenc T.
    Histol. Histopathol. 24:299-308(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Analysis of MCM5 expression in aggressive fibromatosis (desmoid tumor) is reported.
    Source: GeneRIF:4174.

    This publication is mapped to 59 other entries.

  14. 14
    "The minichromosome maintenance proteins 2-7 (MCM2-7) are necessary for RNA polymerase II (Pol II)-mediated transcription."
    Snyder M., Huang X.Y., Zhang J.J.
    J. Biol. Chem. 284:13466-13472(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: the MCM2-7 proteins are co-localized with RNA Pol II on chromatins of constitutively transcribing genes and MCM5 is required for transcription elongation of RNA Pol II.
    Source: GeneRIF:4174.

    This publication is mapped to 28 other entries.

  15. 15
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:4174.

    This publication is mapped to 432 other entries.

  16. 16
    "MCM-2 and MCM-5 expression in gastric adenocarcinoma: clinical significance and comparison with Ki-67 proliferative marker."
    Giaginis C., Giagini A., Tsourouflis G., Gatzidou E., Agapitos E., Kouraklis G., Theocharis S.
    Dig. Dis. Sci. 56:777-785(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: MCM-5 expression was significantly associated with tumor size presence of lymph node metastases and tumor histopathological stage. Patients with high MCM-5 expression had significantly shorter survival times.
    Source: GeneRIF:4174.

    This publication is mapped to 18 other entries.

  17. 17
    "Prediction and diagnosis of bladder cancer recurrence based on urinary content of hTERT, SENP1, PPP1CA, and MCM5 transcripts."
    Brems-Eskildsen A.S., Zieger K., Toldbod H., Holcomb C., Higuchi R., Mansilla F., Munksgaard P.P., Borre M., Orntoft T.F., Dyrskjot L.
    BMC Cancer 10:646-646(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Could use the urinary hTERT SENP1 PPP1CA and MCM5 mRNA to detect bladder cancer recurrence.
    Source: GeneRIF:4174.

    This publication is mapped to 14 other entries.

  18. 18
    Category: Function.
    Annotation: MicroRNA miR-885-5p targets CDK2 and MCM5 activates p53 and inhibits proliferation and survival.
    Source: GeneRIF:4174.

    This publication is mapped to 198 other entries.

  19. 19
    "Minichromosome maintenance (MCM) and AgNOR proteins expression in desmoid tumours: a tissue microarray analysis."
    Ferenc T., Kopczynski J., Stalinska L., Tosik D., Sidor M., Lopaczynska D., Kulig A., Dziki A., Sygut J.
    Folia Histochem. Cytobiol. 48:581-588(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: lack of MCM5 proteins expression which may explain commonly known low mitotic activity of desmoid tumour cells.
    Source: GeneRIF:4174.

    This publication is mapped to 27 other entries.

  20. 20
    Category: Function, Interaction.
    Annotation: Mcm2-7 loads onto origins during initiation as a double hexamer yet does not act as a double-stranded DNA pump during elongation.
    Source: GeneRIF:4174.

    This publication is mapped to 41 other entries.

  21. 21
    "Evaluation of cell proliferation, apoptosis, and DNA-repair genes as potential biomarkers for ethanol-induced CNS alterations."
    Hicks S.D., Lewis L., Ritchie J., Burke P., Abdul-Malak Y., Adackapara N., Canfield K., Shwarts E., Gentile K., Meszaros Z.S., Middleton F.A.
    BMC Neurosci 13:128-128(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: The results of this study demonistrated that Mcm5 shows a highly significant correlation with Alcohol use disorders-induced decreases in the volume of the left parietal supramarginal gyrus and neuropsychological measures.
    Source: GeneRIF:4174.

    This publication is mapped to 16 other entries.

  22. 22
    Category: Interaction.
    Annotation: Data indicate that MCM-BP binds USP7 on chromatin and can mediate an interaction between the USP7 and MCM proteins.
    Source: GeneRIF:4174.

    This publication is mapped to 26 other entries.

  23. 23
    "Increased expression of MCM5 is significantly associated with aggressive progression and poor prognosis of oral squamous cell carcinoma."
    Yu S.Y., Wang Y.P., Chang J.Y., Shen W.R., Chen H.M., Chiang C.P.
    J. Oral Pathol. Med. 43:344-349(2014) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: The increased expression of MCM5 protein begins at the oral pre-cancerous stage and is significantly associated with the aggressive progression and poor prognosis of OSCC.
    Source: GeneRIF:4174.

    This publication is mapped to 8 other entries.

  24. 24
    Category: Interaction.
    Source: IntAct:B1AHB0.

    This publication is mapped to 4105 other entries.

  25. 25
    "MicroRNA-10b and minichromosome maintenance complex component 5 gene as prognostic biomarkers in breast cancer."
    Eissa S., Matboli M., Shehata H.H., Essawy N.O.
    Tumour Biol. 36:4487-4494(2015) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: we could consider miRNA-10b and MCM5 mRNA as prognostic markers and potential therapeutic targets in breast cancer to be applied to other patient data sets.
    Source: GeneRIF:4174.

    This publication is mapped to 8 other entries.

1 to 25 of 35  Show
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