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Protein
Submitted name:

Thy-1 cell surface antigen, isoform CRA_a

Gene

THY1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Thy-1 cell surface antigen, isoform CRA_aImported
Submitted name:
Thy-1 membrane glycoprotein variant 2Imported
Submitted name:
cDNA FLJ33325 fis, clone BNGH42008832, highly similar to THY-1 MEMBRANE GLYCOPROTEINImported
Submitted name:
cDNA FLJ33677 fis, clone BRAWH2002125, highly similar to THY-1 MEMBRANE GLYCOPROTEINImported
Gene namesi
Name:THY1Imported
ORF Names:hCG_14965Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000154096.13

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA36510

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_501429816620 – 161Sequence analysisAdd BLAST142

Expressioni

Gene expression databases

BgeeiENSG00000154096 Expressed in 220 organ(s), highest expression level in anterior cingulate cortex

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiB0YJA4, 1 interactor
B0YJA4, 1 interactor

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 121Ig-likeInterPro annotationAdd BLAST117

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IVXA Eukaryota
ENOG410YYC2 LUCA
HOVERGENiHBG002958
KOiK06514
OMAiTCELRLS

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013106 Ig_V-set
IPR013151 Immunoglobulin
IPR033292 THY1
PANTHERiPTHR19226 PTHR19226, 1 hit
PfamiView protein in Pfam
PF00047 ig, 1 hit
SMARTiView protein in SMART
SM00406 IGv, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

B0YJA4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNLAISIALL LTVLQVSRGQ KVTSLTACLV DQSLRLDCRH ENTSSSPIQY
60 70 80 90 100
EFSLTRETKK HVLFGTVGVP EHTYRSRTNF TSKYNMKVLY LSAFTSKDEG
110 120 130 140 150
TYTCALHHSG HSPPISSQNV TVLRDKLVKC EGISLLAQNT SWLLLLLLSL
160
SLLQATDFMS L
Length:161
Mass (Da):17,935
Last modified:April 8, 2008 - v1
Checksum:i2B6796DA8EE7454B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF445035 Genomic DNA Translation: ACA06081.1
AK090644 mRNA Translation: BAG52205.1
AK090996 mRNA Translation: BAG52259.1
CH471065 Genomic DNA Translation: EAW67488.1
CH471065 Genomic DNA Translation: EAW67490.1
RefSeqiNP_001298089.1, NM_001311160.1
NP_001298091.1, NM_001311162.1
NP_006279.2, NM_006288.4
UniGeneiHs.644697

Genome annotation databases

GeneIDi7070
KEGGihsa:7070

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF445035 Genomic DNA Translation: ACA06081.1
AK090644 mRNA Translation: BAG52205.1
AK090996 mRNA Translation: BAG52259.1
CH471065 Genomic DNA Translation: EAW67488.1
CH471065 Genomic DNA Translation: EAW67490.1
RefSeqiNP_001298089.1, NM_001311160.1
NP_001298091.1, NM_001311162.1
NP_006279.2, NM_006288.4
UniGeneiHs.644697

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB0YJA4, 1 interactor
B0YJA4, 1 interactor

Protocols and materials databases

DNASUi7070
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7070
KEGGihsa:7070

Organism-specific databases

CTDi7070
EuPathDBiHostDB:ENSG00000154096.13
PharmGKBiPA36510

Phylogenomic databases

eggNOGiENOG410IVXA Eukaryota
ENOG410YYC2 LUCA
HOVERGENiHBG002958
KOiK06514
OMAiTCELRLS

Miscellaneous databases

GenomeRNAii7070

Gene expression databases

BgeeiENSG00000154096 Expressed in 220 organ(s), highest expression level in anterior cingulate cortex

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013106 Ig_V-set
IPR013151 Immunoglobulin
IPR033292 THY1
PANTHERiPTHR19226 PTHR19226, 1 hit
PfamiView protein in Pfam
PF00047 ig, 1 hit
SMARTiView protein in SMART
SM00406 IGv, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB0YJA4_HUMAN
AccessioniPrimary (citable) accession number: B0YJA4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 7, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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